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Motivated by an open problem of validating protein identities in label-free shotgun proteomics work-flows, we present a testing procedure to validate class/protein labels using available measurements across instances/peptides. More…

Methodology · Statistics 2020-06-05 Melissa C. Key , Ben Boukai

We propose using performance metrics derived from zero-failure testing to assess binary classifiers. The principal characteristic of the proposed approach is the asymmetric treatment of the two types of error. In particular, we construct a…

Machine Learning · Computer Science 2024-07-08 Ioannis Ivrissimtzis , Matthew Houliston , Shauna Concannon , Graham Roberts

The fundamental task of classification given a limited number of training data samples is considered for physical systems with known parametric statistical models. The standalone learning-based and statistical model-based classifiers face…

Machine Learning · Computer Science 2022-02-01 Alireza Nooraiepour , Waheed U. Bajwa , Narayan B. Mandayam

Class imbalance poses a significant challenge to supervised classification, particularly in critical domains like medical diagnostics and anomaly detection where minority class instances are rare. While numerous studies have explored…

Machine Learning · Computer Science 2025-09-10 Ali Nawaz , Amir Ahmad , Shehroz S. Khan

We show how binary classification methods developed to work on i.i.d. data can be used for solving statistical problems that are seemingly unrelated to classification and concern highly-dependent time series. Specifically, the problems of…

Machine Learning · Computer Science 2013-06-10 Daniil Ryabko , Jérémie Mary

Uncertainty in optimization is often represented as stochastic parameters in the optimization model. In Predict-Then-Optimize approaches, predictions of a machine learning model are used as values for such parameters, effectively…

Machine Learning · Computer Science 2025-12-03 Pieter Smet

In today's data driven world, storing, processing, and gleaning insights from large-scale data are major challenges. Data compression is often required in order to store large amounts of high-dimensional data, and thus, efficient inference…

Machine Learning · Statistics 2018-09-11 Denali Molitor , Deanna Needell

In various situations one is given only the predictions of multiple classifiers over a large unlabeled test data. This scenario raises the following questions: Without any labeled data and without any a-priori knowledge about the…

Machine Learning · Statistics 2014-10-31 Ariel Jaffe , Boaz Nadler , Yuval Kluger

The statistics and machine learning communities have recently seen a growing interest in classification-based approaches to two-sample testing. The outcome of a classification-based two-sample test remains a rejection decision, which is not…

Statistics Theory · Mathematics 2022-11-15 Loris Michel , Jeffrey Näf , Nicolai Meinshausen

An accurate multiclass classification strategy is crucial to interpreting antibody tests. However, traditional methods based on confidence intervals or receiver operating characteristics lack clear extensions to settings with more than two…

Quantitative Methods · Quantitative Biology 2024-05-07 Rayanne A. Luke , Anthony J. Kearsley , Paul N. Patrone

Score-based statistical models play an important role in modern machine learning, statistics, and signal processing. For hypothesis testing, a score-based hypothesis test is proposed in \cite{wu2022score}. We analyze the performance of this…

Signal Processing · Electrical Eng. & Systems 2024-02-06 Enmao Diao , Taposh Banerjee , Vahid Tarokh

Recently, learning with soft labels has been shown to achieve better performance than learning with hard labels in terms of model generalization, calibration, and robustness. However, collecting pointwise labeling confidence for all…

Machine Learning · Computer Science 2023-10-10 Wei Wang , Lei Feng , Yuchen Jiang , Gang Niu , Min-Ling Zhang , Masashi Sugiyama

A common issue for classification in scientific research and industry is the existence of imbalanced classes. When sample sizes of different classes are imbalanced in training data, naively implementing a classification method often leads…

Methodology · Statistics 2021-07-02 Yang Feng , Min Zhou , Xin Tong

This paper introduces a novel multi-stage decision-making model that integrates hypothesis testing and dynamic programming algorithms to address complex decision-making scenarios.Initially,we develop a sampling inspection scheme that…

Systems and Control · Electrical Eng. & Systems 2025-03-11 Ziyang Liu , Yurui Hu , Yihan Deng

We propose a two-sample testing procedure based on learned deep neural network representations. To this end, we define two test statistics that perform an asymptotic location test on data samples mapped onto a hidden layer. The tests are…

Machine Learning · Statistics 2020-03-11 Matthias Kirchler , Shahryar Khorasani , Marius Kloft , Christoph Lippert

The adequate use of information measured in a continuous manner along a period of time represents a methodological challenge. In the last decades, most of traditional statistical procedures have been extended for accommodating these…

Methodology · Statistics 2025-12-04 Pablo Martinez-Camblor

In supervised learning, we often face with ambiguous (A) samples that are difficult to label even by domain experts. In this paper, we consider a binary classification problem in the presence of such A samples. This problem is substantially…

Machine Learning · Computer Science 2020-11-25 Naoya Otani , Yosuke Otsubo , Tetsuya Koike , Masashi Sugiyama

We investigate the discrimination of two candidates of an unknown parameter in quantum systems with continuous weak measurement, inspired by the application of hypothesis testing in distinguish-ing two Hamiltonians [Kiilerich and M{\o}lmer,…

Quantum Physics · Physics 2019-07-24 Beili Gong , Wei Cui

The presence of label noise often misleads the training of deep neural networks. Departing from the recent literature which largely assumes the label noise rate is only determined by the true label class, the errors in human-annotated…

Machine Learning · Computer Science 2021-03-31 Zhaowei Zhu , Tongliang Liu , Yang Liu

Can we learn a binary classifier from only positive data, without any negative data or unlabeled data? We show that if one can equip positive data with confidence (positive-confidence), one can successfully learn a binary classifier, which…

Machine Learning · Statistics 2018-11-29 Takashi Ishida , Gang Niu , Masashi Sugiyama