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Related papers: Dilution with Digital Microfluidic Biochips: How U…

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Digital microfluidic (DMF) biochips are now being extensively used to automate several biochemical laboratory protocols such as clinical analysis, point-of-care diagnostics, and polymerase chain reaction (PCR). In many biological assays,…

Emerging Technologies · Computer Science 2013-07-05 Sukanta Bhattacharjee , Ansuman Banerjee , Tsung-Yi Ho , Krishnendu Chakrabarty , Bhargab B. Bhattacharya

We address the problem of designing micro-fluidic chips for sample preparation, which is a crucial step in many experimental processes in chemical and biological sciences. One of the objectives of sample preparation is to dilute the sample…

Data Structures and Algorithms · Computer Science 2019-11-07 Miguel Coviello Gonzalez , Marek Chrobak

Microfluidic biochips are replacing the conventional biochemical analysers integrating the necessary functions on-chip. We are interested in Flow-Based Microfluidic Biochips (FBMB), where a continuous flow of liquid is manipulated using…

Emerging Technologies · Computer Science 2025-05-07 Alexander Schneider , Jan Madsen , Paul Pop

Microfluidics-based biochips are soon expected to revolutionize clinical diagnosis, DNA sequencing, and other laboratory procedures involving molecular biology. Most microfluidic biochips are based on the principle of continuous fluid flow…

Hardware Architecture · Computer Science 2011-11-09 Fei Su , Krishnendu Chakrabarty

Given the ever-increasing advances of digital microfluidic biochips and their application in a wide range of areas including bio-chemistry experiments, diagnostics, and monitoring purposes like air and water quality control and etc.,…

Emerging Technologies · Computer Science 2020-01-01 Alireza Abdoli

Abstract: In our paper the new algorithm enhanced multi gradient Dilution Preparation (EMDP) is discussed. This new algorithm is reported with a lab on chip or digital Microfluidic biochip to operate multiple operation on a tiny chip. We…

Emerging Technologies · Computer Science 2021-10-04 Meenakshi Sanyal , Somenath Chakraborty

Flow-based microfluidic biochips are widely used in lab- on-a-chip experiments. In these chips, devices such as mixers and detectors connected by micro-channels execute specific operations. Intermediate fluid samples are saved in storage…

Emerging Technologies · Computer Science 2017-05-16 Tsun-Ming Tseng , Bing Li , Tsung-Yi Ho , Ulf Schlichtmann

Effective mixing is essential for biochemical reactions. In droplet-based microfluidics, immediate mixing of substances upon contact in the droplet formation stage can greatly enhance the uniformity of chemical reactions. Furthermore, it…

Design of microfluidic biochips has led to newer challenges to the EDA community due to the availability of various flow-based architectures and the need for catering to diverse applications such as sample preparation, personalized…

Emerging Technologies · Computer Science 2021-07-28 Tapalina Banerjee , Sudip Poddar , Tsung-Yi Ho , Bhargab B. Bhattacharya

In microfluidic systems, droplets undergo intricate deformations as they traverse flow-focusing junctions, posing a challenging task for accurate measurement, especially during short transit times. This study investigates the physical…

Digital Microfluidic Biochips consist of Two Dimensional microarrays that are integrated with different healthcare related cyberphysical systems and expected to be used extensively in near future. Thus, faster and error-free synthesis…

Emerging Technologies · Computer Science 2018-04-10 Sarit Chakraborty , Susanta Chakraborty

Recent advances in digital microfluidic (DMF) technologies offer a promising platform for a wide variety of biochemical applications, such as DNA analysis, automated drug discovery, and toxicity monitoring. For on-chip implementation of…

Emerging Technologies · Computer Science 2022-11-10 Sukanta Bhattacharjee , Ansuman Banerjee , Krishnendu Chakrabarty , Bhargab B. Bhattacharya

Digital microfluidic biochips (DMFBs) constitute modern generation of Lab-on-Chip (LoC) devices aimed at automation, miniaturization and cost-affordability of biochemistry and laboratory procedures. Over the course of past few years there…

Emerging Technologies · Computer Science 2020-08-25 Alireza Abdoli , Ali Jahanian

Digital microfluidic biochips (DMFBs) are revolutionary biomedical devices towards diagnostics and point-of-care applications; the chips provide the capability of performing wide ranges of biochemistry and laboratory procedures, offering…

Emerging Technologies · Computer Science 2020-09-01 Alireza Abdoli , Sedigheh Farhadtoosky , Ali Jahanian

Recent numerical analyses to optimize the design of microfluidic devices for more effective entrapment or segregation of surrogate circulating tumor cells (CTCs) from healthy cells have been reported in the literature without concurrently…

Computational Physics · Physics 2020-06-23 Hakan Başağaoğlu , Justin Blount , Sauro Succi , Christopher J. Freitas

We describe an approach for modeling fluid concentration profiles in grid-based microfluidic chips for fluid mixing. This approach provides an algorithm that predicts fluid concentrations at the chip outlets. Our algorithm significantly…

Computational Engineering, Finance, and Science · Computer Science 2019-11-19 Huong Luu , Marek Chrobak

The Dirichlet Process Gaussian Mixture Model (DPGMM) is often used to cluster data when the number of clusters is unknown. One main DPGMM inference paradigm relies on sampling. Here we consider a known state-of-art sampler (proposed by…

Machine Learning · Computer Science 2022-03-28 Vlad Winter , Or Dinari , Oren Freifeld

Ultrasound-vaporizable microdroplets can be exploited for targeted drug delivery. However, it requires customized microfluidic techniques able to produce monodisperse, capillary-sized and biocompatible multiple emulsions. Recent development…

Soft Condensed Matter · Physics 2019-12-17 E. Teston , V. Hingot , V. Faugeras , C. Errico , M. Bezagu , M. Tanter , O. Couture

Microfluidic devices are gaining attention for their small size and ability to handle tiny fluid volumes. Mixing fluids efficiently at this scale, known as micromixing, is crucial. This article builds upon previous research by introducing a…

A novel micromixing technique that exploit a thrust of droplets into the mixing interface is developed. The technique enhances the mixing by injecting immiscible droplets in a mixing channel and the methodology enables a control of the…

Fluid Dynamics · Physics 2023-03-28 Ryosuke Sakurai , Ken Yamamoto , Masahiro Motosuke
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