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Multiple Sclerosis (MS) is an autoimmune disease that leads to lesions in the central nervous system. Magnetic resonance (MR) images provide sufficient imaging contrast to visualize and detect lesions, particularly those in the white…

Computer Vision and Pattern Recognition · Computer Science 2018-03-28 Snehashis Roy , John A. Butman , Daniel S. Reich , Peter A. Calabresi , Dzung L. Pham

Multiple sclerosis (MS) is a chronic inflammatory and degenerative disease of the central nervous system, characterized by the appearance of focal lesions in the white and gray matter that topographically correlate with an individual…

Computer Vision and Pattern Recognition · Computer Science 2022-01-31 Yang Ma , Chaoyi Zhang , Mariano Cabezas , Yang Song , Zihao Tang , Dongnan Liu , Weidong Cai , Michael Barnett , Chenyu Wang

Multiple sclerosis is an inflammatory autoimmune demyelinating disease that is characterized by lesions in the central nervous system. Typically, magnetic resonance imaging (MRI) is used for tracking disease progression. Automatic image…

Image and Video Processing · Electrical Eng. & Systems 2020-08-06 Nils Gessert , Julia Krüger , Roland Opfer , Ann-Christin Ostwaldt , Praveena Manogaran , Hagen H. Kitzler , Sven Schippling , Alexander Schlaefer

Multiple sclerosis (MS) is a demyelinating disease that affects more than 2 million people worldwide. The most used imaging technique to help in its diagnosis and follow-up is magnetic resonance imaging (MRI). Fluid Attenuated Inversion…

Computer Vision and Pattern Recognition · Computer Science 2018-07-26 Paulo G. L. Freire , Ricardo J. Ferrari

Introduction: Multiple Sclerosis (MS) is a chronic disease that affects millions of people across the globe. MS can critically affect different organs of the central nervous system such as the eyes, the spinal cord, and the brain.…

Image and Video Processing · Electrical Eng. & Systems 2023-02-21 Atif Shah , Maged S. Al-Shaibani , Moataz Ahmad , Reem Bunyan

Objective: Multiple Sclerosis (MS) is an autoimmune, and demyelinating disease that leads to lesions in the central nervous system. This disease can be tracked and diagnosed using Magnetic Resonance Imaging (MRI). Up to now a multitude of…

Image and Video Processing · Electrical Eng. & Systems 2022-01-07 Mehdi SadeghiBakhi , Hamidreza Pourreza , Hamidreza Mahyar

Lesion segmentation is a core task for quantitative analysis of MRI scans of Multiple Sclerosis patients. The recent success of deep learning techniques in a variety of medical image analysis applications has renewed community interest in…

Image and Video Processing · Electrical Eng. & Systems 2020-12-29 Huahong Zhang , Ipek Oguz

Cortical lesions (CLs) have emerged as valuable biomarkers in multiple sclerosis (MS), offering high diagnostic specificity and prognostic relevance. However, their routine clinical integration remains limited due to subtle magnetic…

In multiple sclerosis, lesions interfere with automated magnetic resonance imaging analyses such as brain parcellation and deformable registration, while lesion segmentation models are hindered by the limited availability of annotated…

Structural magnetic resonance imaging (MRI) can be used to detect lesions in the brains of multiple sclerosis (MS) patients. The formation of these lesions is a complex process involving inflammation, tissue damage, and tissue repair, all…

Multiple Sclerosis (MS) is a chronic autoimmune disease that can significantly reduce the quality of life of a patient. Existing treatment options can only help slow down the progression of the disease. Therefore, early detection and…

Computer Vision and Pattern Recognition · Computer Science 2026-05-12 Abdul Basit , Ashir Rashid , Muhammad Abdullah Hanif , Muhammad Shafique

The detection of new or enlarged white-matter lesions in multiple sclerosis is a vital task in the monitoring of patients undergoing disease-modifying treatment for multiple sclerosis. However, the definition of 'new or enlarged' is not…

Lesions in central nervous system (CNS) and their growth leads to debilitating diseases like Multiple Sclerosis (MS), Alzheimer's etc. We developed a model earlier which shows how the lesion growth can be arrested through a beneficial…

Adaptation and Self-Organizing Systems · Physics 2012-09-04 Mathankumar Raja , T. R. Krishna Mohan

Automatic magnetic resonance (MR) image processing pipelines are widely used to study people with multiple sclerosis (PwMS), encompassing tasks such as lesion segmentation and brain parcellation. However, the presence of lesion often…

Image and Video Processing · Electrical Eng. & Systems 2024-10-08 Jinwei Zhang , Lianrui Zuo , Yihao Liu , Samuel Remedios , Bennett A. Landman , Jerry L. Prince , Aaron Carass

A simulation model for the spread and control of lesions in the brain is constructed using a planar network (graph) representation for the Central Nervous System (CNS). The model is inspired by the lesion structures observed in the case of…

Biological Physics · Physics 2007-08-27 T. R. Krishna Mohan

In this paper, we propose generating synthetic multiple sclerosis (MS) lesions on MRI images with the final aim to improve the performance of supervised machine learning algorithms, therefore avoiding the problem of the lack of available…

Computer Vision and Pattern Recognition · Computer Science 2019-01-18 Mostafa Salem , Sergi Valverde , Mariano Cabezas , Deborah Pareto , Arnau Oliver , Joaquim Salvi , Àlex Rovira , Xavier Lladó

In this paper, we present an automated approach for segmenting multiple sclerosis (MS) lesions from multi-modal brain magnetic resonance images. Our method is based on a deep end-to-end 2D convolutional neural network (CNN) for slice-based…

Computer Vision and Pattern Recognition · Computer Science 2019-04-09 Shahab Aslani , Michael Dayan , Loredana Storelli , Massimo Filippi , Vittorio Murino , Maria A Rocca , Diego Sona

In this paper, we present a novel automated method for White Matter (WM) lesion segmentation of Multiple Sclerosis (MS) patient images. Our approach is based on a cascade of two 3D patch-wise convolutional neural networks (CNN). The first…

Multiple Sclerosis (MS) is a severe neurological disease characterized by inflammatory lesions in the central nervous system. Hence, predicting inflammatory disease activity is crucial for disease assessment and treatment. However, MS…

Image and Video Processing · Electrical Eng. & Systems 2023-09-01 Chinmay Prabhakar , Hongwei Bran Li , Johannes C. Paetzold , Timo Loehr , Chen Niu , Mark Mühlau , Daniel Rueckert , Benedikt Wiestler , Bjoern Menze

Multiple Sclerosis (MS) and microvascular leukoencephalopathy are two distinct neurological conditions, the first caused by focal autoimmune inflammation in the central nervous system, the second caused by chronic white matter damage from…

Image and Video Processing · Electrical Eng. & Systems 2021-01-19 Christopher Vogelsanger , Christian Federau
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