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Spatial separation of suspended particles based on contrast in their physical or chemical properties forms the basis of various biological assays performed on lab-on-achip devices. To electronically acquire this information, we have…

Emerging Technologies · Computer Science 2018-08-13 Ningquan Wang , Ruxiu Liu , Roozbeh Khodambashi , Norh Asmare , A. Fatih Sarioglu

Embedded devices are omnipresent in modern networks including the ones operating inside critical environments. However, due to their constrained nature, novel mechanisms are required to provide external, and non-intrusive anomaly detection.…

Cryptography and Security · Computer Science 2023-02-07 Kurt A. Vedros , Georgios Michail Makrakis , Constantinos Kolias , Robert C. Ivans , Craig Rieger

Whereas entropy can induce phase behavior that is as rich as seen in energetic systems, microphase separation remains a very rare phenomenon in entropic systems. In this paper, we present a density functional approach to study the…

Soft Condensed Matter · Physics 2009-11-10 Paul P. F. Wessels , Bela M. Mulder

Using Brownian dynamics simulations, we study the migration of long charged chains in an electrophoretic microchannel device consisting of an array of microscopic entropic traps with alternating deep regions and narrow constrictions. Such a…

Biological Physics · Physics 2007-05-23 Martin Streek , Friederike Schmid , Thanh Tu Duong , Alexandra Ros

Rapid and reproducible assembly of aligned nanostructures on a wafer-scale is a crucial, yet one of the most challenging tasks in the incorporation of nanowires into integrated circuits. We present the synthesis of a periodic nanochannel…

The dielectrophoresis method for trapping and attaching nanoscale double-stranded DNA between nanoelectrodes was developed. The method gives a high yield of trapping single or a few molecules only which enables transport measurements at the…

Soft Condensed Matter · Physics 2007-05-23 S. Tuukkanen , A. Kuzyk , J. J. Toppari , V. P. Hytonen , T. Ihalainen , P. Torma

Due to the low conductivity of pure water, using an electrolyte is common for achieving efficient water electrolysis. In this paper, we have broken through this common sense by using deep-sub-Debye-length nanogap electrochemical cells for…

Chemical Physics · Physics 2016-11-16 Yifei Wang , S. R. Narayanan , Wei Wu

The detection of quantal exocytic events from neurons and neuroendocrine cells is a challenging task in neuroscience. One of the most promising platforms for the development of a new generation of biosensors is diamond, due to its…

Instrumentation and Detectors · Physics 2016-08-30 F. Picollo , A. Battiato , E. Carbone , L. Croin , E. Enrico , J. Forneris , S. Gosso , P. Olivero , A. Pasquarelli , V. Carabelli

Electrical neural signalling typically takes place at the time-scale of milliseconds, and is typically modeled using the cable equation. This is a good approximation for processes when ionic concentrations vary little during the time course…

Cell Behavior · Quantitative Biology 2014-03-05 Geir Halnes , Ivar Østby , Klas H. Pettersen , Stig W. Omholt , Gaute T. Einevoll

The recently developed energy conserving semi-implicit method (ECsim) for PIC simulation is applied to multiple scale problems where the electron-scale physics needs to be only partially retained and the interest is on the macroscopic or…

Computational Physics · Physics 2017-05-24 Giovanni Lapenta , Diego Gonzalez-Herrero , Elisabetta Boella

Large-scale neural recording with high spatio-temporal resolution is essential for understanding information processing in brain, yet current neural interfaces fall far short of comprehensively capturing brain activity due to extremely high…

Metastases are the primary cause of death in cancer patients. Small animal models are helping in dissecting some of key features in the metastatic cascade. Yet, tools for systematically analyze the contribution of blood flow, vascular…

Cell Behavior · Quantitative Biology 2019-07-31 Hilaria Mollica , Roberto Palomba , Rosita Primavera , Paolo Decuzzi

Electron backscatter diffraction (EBSD) has developed over the last few decades into a valuable crystallographic characterisation method for a wide range of sample types. Despite these advances, issues such as the complexity of sample…

Image and Video Processing · Electrical Eng. & Systems 2024-07-17 Zoë Broad , Alex W. Robinson , Jack Wells , Daniel Nicholls , Amirafshar Moshtaghpour , Angus I. Kirkland , Nigel D. Browning

Dissipative Particle Dynamics (DPD) is becoming a popular particle based method to study flow through microchannels due to the ease with which the presence of biological cells or DNA chains can be modeled. Many Lab-On-Chip (LOC) devices…

Fluid Dynamics · Physics 2013-03-27 S. Kumar Ranjith , B. S. V. Patnaik , Srikanth Vedantam

Graphene stands as a promising material with vast potential across energy storage, electronics, etc. Here, we present a novel mechanical approach utilizing ultrasonic high-energy intercalation exfoliation to extract monolayer graphene from…

Materials Science · Physics 2025-01-15 Kaitong Sun , Si Wu , Junchao Xia , Yinghao Zhu , Guanping Xu , Hai-Feng Li

Identification of non-amplified DNA sequences and single-base mutations is essential for molecular biology and genetic diagnostics. This paper reports a novel sensor consisting of electrochemically-gated graphene coplanar waveguides coupled…

The renewable energy sector critically needs low-cost and environmentally neutral energy storage solutions throughout the entire device life cycle. However, the limited performance of standard water-based electrochemical systems prevents…

The recent development of deep learning large models in medicine shows remarkable performance in medical image analysis and diagnosis, but their large number of parameters causes memory and inference latency challenges. Knowledge…

Computer Vision and Pattern Recognition · Computer Science 2024-09-19 Shaojie Li , Zhaoshuo Diao

Solid-state nanopore and nanopipette sensors are powerful devices for the detection, quantification and structural analysis of biopolymers such as DNA and proteins, especially in carrier-enhanced resistive-pulse sensing. However, hundreds…

Mesoscale and Nanoscale Physics · Physics 2025-10-14 Cengiz J. Khan , Oliver J. Irving , Rand A. Al-Waqfi , Giorgio Ferrari , Tim Albrecht

We utilize multilevel atoms trapped in a driven resonant optical cavity to produce scalable multi-mode squeezed states for quantum sensing and metrology. While superradiance or collective dissipative emission by itself has been typically a…

Quantum Physics · Physics 2024-01-22 Bhuvanesh Sundar , Diego Barbarena , Ana Maria Rey , Asier Piñeiro Orioli