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Related papers: Precise spatial scaling in the early fly embryo

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DNA synthesis in \textit{Xenopus} frog embryos initiates stochastically in time at many sites (origins) along the chromosome. Stochastic initiation implies fluctuations in the time to complete and may lead to cell death if replication takes…

Cell Behavior · Quantitative Biology 2016-11-03 Scott Cheng-Hsin Yang , John Bechhoefer

Dislocation patterning and self-organization during plastic deformation are associated with work hardening, but the exact mechanisms remain elusive. This is partly because studies of the structure and local strain during the initial stages…

Insects exhibit remarkable cognitive skills in the field and several cognitive abilities have been demonstrated in Drosophila in the laboratory. By devising an ethologically relevant experimental setup that also allows comparison of…

Neurons and Cognition · Quantitative Biology 2016-02-17 Shay Cohen , Yoav Benjamini , Ilan Golani

We measure different contributions to entropy production in a living functional epithelial tissue. We do this by extracting the functional dynamics of development while at the same time quantifying fluctuations. Using the translucent…

Soft Condensed Matter · Physics 2023-01-25 Mark Olenik , Jake Turley , Stephen Cross , Helen Weavers , Paul Martin , Isaac Chenchiah , Tanniemola Liverpool

Molecular and morphological characters, as important parts of biological taxonomy, are contradictory but need to be integrated. Organism's image recognition and bioinformatics are emerging and hot problems nowadays but with a gap between…

Computer Vision and Pattern Recognition · Computer Science 2022-06-29 Jiewen Xiao , Wenbin Liao , Ming Zhang , Jing Wang , Jianxin Wang , Yihua Yang

Many growth processes lead to intriguing stochastic patterns and complex fractal structures which exhibit local scale invariance properties. Such structures can often be described effectively by space-time trajectories of interacting…

Statistical Mechanics · Physics 2013-06-07 Adnan Ali , Robin C. Ball , Stefan Grosskinsky , Ellak Somfai

During developmental processes such as embryogenesis, how a group of cells fold into specific structures, is a central question in biology that defines how living organisms form. Establishing tissue-level morphology critically relies on how…

Soft Condensed Matter · Physics 2024-07-23 Haiqian Yang , Anh Q. Nguyen , Dapeng Bi , Markus J. Buehler , Ming Guo

Understanding cell fate patterning and morphogenesis in the mammalian embryo remains a formidable challenge. Recently, in vivo models based on embryonic stem cells (ESCs) have emerged as complementary methods to quantitatively dissect the…

Tissues and Organs · Quantitative Biology 2017-12-12 Eric D. Siggia , Aryeh Warmflash

Search for possible relationships between phylogeny and ontogeny is one of the most important issues in the field of evolutionary developmental biology. By representing developmental dynamics of spatially located cells with gene expression…

Populations and Evolution · Quantitative Biology 2015-04-01 Takahiro Kohsokabe , Kunihiko Kaneko

We investigate the possibility of a striped inhomoegenous phase occurring as an electronic system with an order parameter linearly coupled to the elastic degrees of freedom is tuned through the electronic phase transition. We find that in…

Strongly Correlated Electrons · Physics 2023-03-23 Giuliano Chiriacò , Andrew J. Millis

We consider active-sterile neutrino oscillations in the early universe in an inhomogeneous isocurvature background. We show that very small initial baryonic seed-inhomogeneities can trigger a growth of very large amplitude spatial…

High Energy Physics - Phenomenology · Physics 2009-10-31 Kari Enqvist , Kimmo Kainulainen , Antti Sorri

A crucial step in the early development of multicellular organisms involves the establishment of spatial patterns of gene expression which later direct proliferating cells to take on different cell fates. These patterns enable the cells to…

Molecular Networks · Quantitative Biology 2017-02-08 Patrick Hillenbrand , Ulrich Gerland , Gasper Tkacik

We develop a simple computational model for cell boundary evolution in plastic deformation. We study the cell boundary size distribution and cell boundary misorientation distribution that experimentally have been found to have scaling forms…

Materials Science · Physics 2013-05-29 James P. Sethna , Valerie R. Coffman , Eugene Demler

We consider the spatial Lambda-Fleming-Viot process model for frequencies of genetic types in a population living in R^d, in the special case in which there are just two types of individual, labelled 0 and 1. At time zero, everyone in the…

Probability · Mathematics 2011-11-28 N. Berestycki , A. M. Etheridge , A. Veber

This is the first paper of a series investigating the scaling relations of early-type galaxies in clusters. Here we illustrate the multi-band imagery and the image reduction and calibration procedures relative to the whole sample of 22…

Astrophysics · Physics 2009-11-07 G. Fasano , D. Bettoni , M. D'Onofrio , P. Kjaergaard , M. Moles

Here we present the first method for tracking each leg of a fruit fly behaving spontaneously upon a trackball, in real time. Legs were tracked with infrared-fluorescent dye invisible to the fly, and compatible with two-photon microscopy and…

Neurons and Cognition · Quantitative Biology 2015-06-11 Jamey Kain , Chris Stokes , Quentin Gaudry , Xiangzhi Song , James Foley , Rachel Wilson , Benjamin de Bivort

In proliferating epithelia of mammalian skin, cells of irregular polygonal-like shapes pack into complex nearly flat two-dimensional structures that are pliable to deformations. In this work, we employ various sensitive correlation…

Statistical Mechanics · Physics 2016-12-07 Duyu Chen , Wen Yih Aw , Danelle Devenport , Salvatore Torquato

During the first years of life, the human brain undergoes dynamic spatially-heterogeneous changes, involving differentiation of neuronal types, dendritic arborization, axonal ingrowth, outgrowth and retraction, synaptogenesis, and…

Transcription factors (TFs) are key regulators of gene expression. Based on the classical scenario in which the TF search process switches between one-dimensional motion along the DNA molecule and free Brownian motion in the nucleus, we…

Genomics · Quantitative Biology 2010-10-15 Godefroy Malherbe , David Holcman

We experimentally probe complex bio-photonic architecture of microstructures on the transparent insect wings by a simple, non-invasive, real time optical technique. A stable and reproducible far-field diffraction pattern in transmission was…

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