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A diffusion molecular channel is a channel with memory, as molecules released into the medium hit the receptors after a random delay. Coding over the diffusion channel is performed by choosing the type, intensity, or the released time of…

Channel memory and inter-symbol interference (ISI) are harmful factors in diffusion-based molecular communication (DBMC) between bionanosensors. To tackle these problems, this paper proposes a lightweight ISI-mitigating coding scheme to…

Information Theory · Computer Science 2023-05-24 Dongliang Jing , Andrew W. Eckford

Molecular communication is a new field of communication where molecules are used to transfer information. Among the proposed methods, molecular communication via diffusion (MCvD) is particularly effective. One of the main challenges in MCvD…

Emerging Technologies · Computer Science 2014-10-31 Burcu Tepekule , Ali E. Pusane , H. Birkan Yilmaz , Chan-Byoung Chae , Tuna Tugcu

This letter introduces a novel algorithm for generating codebooks in molecular communications (MC). The proposed algorithm utilizes character entropy to effectively mitigate inter-symbol interference (ISI) during MC via diffusion. Based on…

Information Theory · Computer Science 2023-06-07 Haewoong Hyun Changmin Lee , Miaowen Wen , Sang-Hyo Kim , Chan-Byoung Chae

In this paper, we propose a novel inter-symbol interference (ISI) mitigation scheme for molecular communication via diffusion (MCvD) systems with the optimal detection interval. Its rationale is to exploit the discarded duration (i.e., the…

Signal Processing · Electrical Eng. & Systems 2022-07-21 Xuan Chen , Fei Ji , Miaowen Wen , Yu Huang , Yuankun Tang , Andrew W. Eckford

Intersymbol Interference (ISI) has a detrimental impact on any Molecular Communication via Diffusion (MCvD) system. Also, the receiver noise can severely degrade the MCvD channel performance. However, the channel codes proposed in the…

Information Theory · Computer Science 2025-02-28 Tamoghno Nath , Krishna Gopal Benerjee , Adrish Banerjee

In this paper, a simple memory limited transmitter for molecular communication is proposed, in which information is encoded in the diffusion rate of the molecules. Taking advantage of memory, the proposed transmitter reduces the ISI problem…

Information Theory · Computer Science 2014-10-30 Mohammad Movahednasab , Mehdi Soleimanifar , Amin Gohari , Masoumeh Nasiri Kenari , Urbashi Mitra

This paper studies the mitigation of intersymbol interference in a diffusive molecular communication system using enzymes that freely diffuse in the propagation environment. The enzymes form reaction intermediates with information molecules…

Information Theory · Computer Science 2014-01-21 Adam Noel , Karen C. Cheung , Robert Schober

While molecular communication via diffusion experiences significant inter-symbol interference (ISI), recent work suggests that ISI can be mitigated via time differentiation pre-processing which achieves pulse narrowing. Herein, the approach…

Information Theory · Computer Science 2021-08-19 Mustafa Can Gursoy , Urbashi Mitra

This paper considers the problem of channel coding over Gaussian intersymbol interference (ISI) channels with a given metric decoding rule. Specifically, it is assumed that the mismatched decoder has an incorrect assumption on the impulse…

Information Theory · Computer Science 2017-06-20 Wasim Huleihel , Salman Salamatian , Neri Merhav , Muriel Médard

Molecular communication suffers from severe inter-symbol interference, which makes constrained coding essential for reliable transmission. Run-length-limited ISI-mitigation codes are attractive because they select low-weight constrained…

Information Theory · Computer Science 2026-05-01 Melih Şahin , Ozgur B. Akan

Diffusive molecular communications (DiMC) have recently gained attention as a candidate for nano- to micro- and macro-scale communications due to its simplicity and energy efficiency. As signal propagation is solely enabled by Brownian…

Information Theory · Computer Science 2021-01-11 Mustafa Can Gursoy , Masoumeh Nasiri-Kenari , Urbashi Mitra

Intersymbol Interference (ISI) is a major bottleneck in Molecular Communication via Diffusion (MCvD), degrading system performance. This paper introduces two families of linear channel codes to mitigate ISI: Zero Pad Zero Start (ZPZS) and…

Information Theory · Computer Science 2025-07-01 Tamoghno Nath , Krishna Gopal Benerjee , Adrish Banerjee

A universal decoding procedure is proposed for the intersymbol interference (ISI) Gaussian channels. The universality of the proposed decoder is in the sense of being independent of the various channel parameters, and at the same time,…

Information Theory · Computer Science 2014-03-18 Wasim Huleihel , Neri Merhav

Molecular communication has a key role to play in future medical applications, including detecting, analyzing, and addressing infectious disease outbreaks. Overcoming inter-symbol interference (ISI) is one of the key challenges in the…

Information Theory · Computer Science 2022-04-20 Xuan Chen , Miaowen Wen , Fei Ji , Yu Huang , Yuankun Tang , Andrew W. Eckford

Molecular communication (MC) offers a groundbreaking approach to communication inspired by biological signaling. It is particularly suited for environments where traditional electromagnetic methods fail, such as fluid mediums or within the…

Molecular Networks · Quantitative Biology 2025-03-18 Aravind Muraleedharan , Abhishek K. Gupta

In this paper, a diffusion-based molecular communication channel between two nano-machines is considered. The effect of the amount of memory on performance is characterized, and a simple memory-limited decoder is proposed and its…

Biological Physics · Physics 2014-05-05 Reza Mosayebi , Hamidreza Arjmandi , Amin Gohari , Masoumeh Nasiri Kenari , Urbashi Mitra

In this paper, we design matched filters for diffusive molecular communication systems taking into account the following impairments: signal-dependent diffusion noise, inter-symbol interference (ISI), and external interfering molecules. The…

Information Theory · Computer Science 2017-05-05 Vahid Jamali , Arman Ahmadzadeh , Robert Schober

In diffusion-based molecular communication, information transport is governed by diffusion through a fluid medium. The achievable data rates for these channels are very low compared to the radio-based communication system, since diffusion…

Emerging Technologies · Computer Science 2016-03-15 Bon-Hong Koo , Changmin Lee , H. Birkan Yilmaz , Nariman Farsad , Andrew Eckford , Chan-Byoung Chae

In this paper, we present an analytical framework to derive the performance of a molecular communication system where a transmitter bio-nano-machine (TBN) is communicating with a fully-absorbing spherical receiver bio-nano-machine (RBN) in…

Information Theory · Computer Science 2020-04-07 Nithin V. Sabu , Abhishek K. Gupta
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