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Robust planning in interactive scenarios requires predicting the uncertain future to make risk-aware decisions. Unfortunately, due to long-tail safety-critical events, the risk is often under-estimated by finite-sampling approximations of…

Machine Learning · Computer Science 2023-01-13 Haruki Nishimura , Jean Mercat , Blake Wulfe , Rowan McAllister , Adrien Gaidon

Background: The stochastic behavior of patient arrival at an emergency department (ED) complicates the management of an ED. More than 50% of hospitals ED capacity tends to operate beyond its normal capacity and eventually fails to deliver…

Computers and Society · Computer Science 2019-01-10 Avishek Choudhury

Clinical time-series forecasting is increasingly studied for decision support, yet standard aggregate metrics can obscure whether a model is actually useful for the task it is meant to serve. In safety-critical settings, low average error…

Machine Learning · Computer Science 2026-05-04 Alireza Namazi , Heman Shakeri

Many economies are challenged by the effects of an ageing population, particularly in sectors where resource capacity planning is critical, such as healthcare. This research addresses the operational challenges of bed and staffing capacity…

Machine Learning · Computer Science 2025-04-25 Elizabeth Williams , Daniel Gartner , Paul Harper

The consideration of predictive uncertainty in medical imaging with deep learning is of utmost importance. We apply estimation of both aleatoric and epistemic uncertainty by variational Bayesian inference with Monte Carlo dropout to…

Image and Video Processing · Electrical Eng. & Systems 2021-04-27 Max-Heinrich Laves , Sontje Ihler , Jacob F. Fast , Lüder A. Kahrs , Tobias Ortmaier

Hospital readmission rate is high for heart failure patients. Early detection of deterioration will help doctors prevent readmissions, thus reducing health care cost and providing patients with just-in-time intervention. Wearable devices…

Computers and Society · Computer Science 2018-06-05 Dingwen Li , Jay Vaidya , Michael Wang , Ben Bush , Chenyang Lu , Marin Kollef , Thomas Bailey

In cancer epidemiology using population-based data, regression models for the excess mortality hazard is a useful method to estimate cancer survival and to describe the association between prognosis factors and excess mortality. This method…

Methodology · Statistics 2019-04-19 Francisco J. Rubio , Bernard Rachet , Roch Giorgi , Camille Maringe , Aurelien Belot

Problem definition: Access to accurate predictions of patients' outcomes can enhance medical staff's decision-making, which ultimately benefits all stakeholders in the hospitals. A large hospital network in the US has been collaborating…

Health risk prediction is one of the fundamental tasks under predictive modeling in the medical domain, which aims to forecast the potential health risks that patients may face in the future using their historical Electronic Health Records…

Machine Learning · Computer Science 2023-10-09 Yuan Zhong , Suhan Cui , Jiaqi Wang , Xiaochen Wang , Ziyi Yin , Yaqing Wang , Houping Xiao , Mengdi Huai , Ting Wang , Fenglong Ma

We present an optimized rerandomization design procedure for a non-sequential treatment-control experiment. Randomized experiments are the gold standard for finding causal effects in nature. But sometimes random assignments result in…

Methodology · Statistics 2021-01-26 Adam Kapelner , Abba M. Krieger , Michael Sklar , David Azriel

Motivated by modern applications such as computerized adaptive testing, sequential rank aggregation, and heterogeneous data source selection, we study the problem of active sequential estimation, which involves adaptively selecting…

Statistics Theory · Mathematics 2024-02-14 Xiaoou Li , Hongru Zhao

We intend to create a new risk assessment methodology that combines the best characteristics of both risk score and machine learning models. More specifically, we aim to develop a method that, besides having a good performance, offers a…

Machine Learning · Computer Science 2021-10-19 Francisco Valente , Jorge Henriques , Simão Paredes , Teresa Rocha , Paulo de Carvalho , João Morais

Encompassing numerous nationwide, statewide, and institutional initiatives in the United States, provider profiling has evolved into a major health care undertaking with ubiquitous applications, profound implications, and high-stakes…

Time-to-event endpoints are central to evaluate treatment efficacy across many disease areas. Many trial protocols include interim analyses within group-sequential designs that control type I error via spending functions or boundary…

Methodology · Statistics 2026-01-19 Edoardo Ratti , Federico L. Perlino , Stefania Galimberti , Maria G. Valsecchi

In healthcare, clinical risks are crucial for treatment decisions, yet the analysis of their associations is often overlooked. This gap is particularly significant when balancing risks that are weighed against each other, as in the case of…

Applications · Statistics 2024-06-03 Yajie Duan , Javier Cabrera , Davit Sargsyan

With the rising importance of large-scale network control, the problem of actuator placement has received increasing attention. Our goal in this paper is to find a set of actuators minimizing the metric that measures the average energy…

Optimization and Control · Mathematics 2021-07-14 Baiwei Guo , Orcun Karaca , Tyler Summers , Maryam Kamgarpour

An adaptive scheme to generate reduced-order models for parametric nonlinear dynamical systems is proposed. It aims to automatize the POD-Greedy algorithm combined with empirical interpolation. At each iteration, it is able to adaptively…

Numerical Analysis · Mathematics 2021-10-13 Sridhar Chellappa , Lihong Feng , Peter Benner

This paper focuses on the development of novel greedy techniques for distributed learning under sparsity constraints. Greedy techniques have widely been used in centralized systems due to their low computational requirements and at the same…

Information Theory · Computer Science 2015-06-23 Symeon Chouvardas , Gerasimos Mileounis , Nicholas Kalouptsidis , Sergios Theodoridis

Identifying optimal medical treatments to improve survival has long been a critical goal of pharmacoepidemiology. Traditionally, we use an average treatment effect measure to compare outcomes between treatment plans. However, new methods…

Clinicians need to predict patient outcomes with high accuracy as early as possible after disease inception. In this manuscript, we show that patient-to-patient variability sets a fundamental limit on outcome prediction accuracy for a…

Quantitative Methods · Quantitative Biology 2016-02-17 Manuel Mai , Kun Wang , Greg Huber , Michael Kirby , Mark D. Shattuck , Corey S. O'Hern