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The intensive care unit (ICU) comprises a complex hospital environment, where decisions made by clinicians have a high level of risk for the patients' lives. A comprehensive care pathway must then be followed to reduce p complications.…

Readmission following discharge from an initial hospitalization is a key marker of quality of health care in the United States. For the most part, readmission has been used to study quality of care for patients with acute health conditions,…

Applications · Statistics 2017-11-21 Kyu Ha Lee , Francesca Dominici , Deborah Schrag , Sebastien Haneuse

Readmission after discharge from a hospital is disruptive and costly, regardless of the reason. However, it can be particularly problematic for psychiatric patients, so predicting which patients may be readmitted is critically important but…

Computation and Language · Computer Science 2018-09-18 Eben Holderness , Nicholas Miller , Philip Cawkwell , Kirsten Bolton , James Pustejovsky , Marie Meteer , Mei-Hua Hall

The management of hyperglycemia in hospitalized patients has a significant impact on both morbidity and mortality. Therefore, it is important to predict the need for diabetic patients to be hospitalized. However, using standard machine…

Artificial Intelligence · Computer Science 2022-08-02 Shaina Raza

Readmission prediction is a critical but challenging clinical task, as the inherent relationship between high-dimensional covariates and readmission is complex and heterogeneous. Despite this complexity, models should be interpretable to…

Methodology · Statistics 2025-07-10 Wei Wang , Angela Bailey , Christopher Tignanelli , Jared D. Huling

Although not without controversy, readmission is entrenched as a hospital quality metric, with statistical analyses generally based on fitting a logistic-Normal generalized linear mixed model. Such analyses, however, ignore death as a…

Artificial intelligence, and particularly machine learning (ML), is increasingly developed and deployed to support healthcare in a variety of settings. However, clinical decision support (CDS) technologies based on ML need to be portable if…

Machine Learning · Computer Science 2022-07-07 Steve Nyemba , Chao Yan , Ziqi Zhang , Amol Rajmane , Pablo Meyer , Prithwish Chakraborty , Bradley Malin

Objective: To compare different deep learning architectures for predicting the risk of readmission within 30 days of discharge from the intensive care unit (ICU). The interpretability of attention-based models is leveraged to describe…

Machine Learning · Computer Science 2020-01-08 Sebastiano Barbieri , James Kemp , Oscar Perez-Concha , Sradha Kotwal , Martin Gallagher , Angus Ritchie , Louisa Jorm

This paper addresses patient heterogeneity associated with prediction problems in biomedical applications. We propose a systematic hypothesis testing approach to determine the existence of patient subgroup structure and the number of…

Methodology · Statistics 2021-01-08 Xu Gao , Weining Shen , Jing Ning , Ziding Feng , Jianhua Hu

Medical events of interest, such as mortality, often happen at a low rate in electronic medical records, as most admitted patients survive. Training models with this imbalance rate (class density discrepancy) may lead to suboptimal…

Machine Learning · Computer Science 2022-08-02 Zepeng Huo , Xiaoning Qian , Shuai Huang , Zhangyang Wang , Bobak J. Mortazavi

Predicting which patients are more likely to be readmitted to a hospital within 30 days after discharge is a valuable piece of information in clinical decision-making. Building a successful readmission risk classifier based on the content…

Risk adjustment has become an increasingly important tool in healthcare. It has been extensively applied to payment adjustment for health plans to reflect the expected cost of providing coverage for members. Risk adjustment models are…

Machine Learning · Computer Science 2019-07-16 Qiu-Yue Zhong , Andrew H. Fairless , Jasmine M. McCammon , Farbod Rahmanian

We consider a patient risk models which has access to patient features such as vital signs, lab values, and prior history but does not have access to a patient's diagnosis. For example, this occurs in a model deployed at intake time for…

Artificial Intelligence · Computer Science 2023-07-03 Alexander Peysakhovich , Rich Caruana , Yin Aphinyanaphongs

Outcome prediction from clinical text can prevent doctors from overlooking possible risks and help hospitals to plan capacities. We simulate patients at admission time, when decision support can be especially valuable, and contribute a…

Computation and Language · Computer Science 2021-02-09 Betty van Aken , Jens-Michalis Papaioannou , Manuel Mayrdorfer , Klemens Budde , Felix A. Gers , Alexander Löser

After admission to emergency department (ED), patients with critical illnesses are transferred to intensive care unit (ICU) due to unexpected clinical deterioration occurrence. Identifying such unplanned ICU transfers is urgently needed for…

Machine Learning · Computer Science 2021-02-10 Chun-An Chou , Qingtao Cao , Shao-Jen Weng , Che-Hung Tsai

Heart failure hospitalization is a severe burden on healthcare. How to predict and therefore prevent readmission has been a significant challenge in outcomes research. To address this, we propose a deep learning approach to predict…

Computation and Language · Computer Science 2019-12-24 Xiong Liu , Yu Chen , Jay Bae , Hu Li , Joseph Johnston , Todd Sanger

Time-to-event models are commonly used to study associations between risk factors and disease outcomes in the setting of electronic health records (EHR). In recent years, focus has intensified on social determinants of health, highlighting…

Applications · Statistics 2025-11-26 Yueming Shen , Christian Pean , David Dunson , Samuel Berchuck

Planning under uncertainty is a crucial capability for autonomous systems to operate reliably in uncertain and dynamic environments. The concern of safety becomes even more critical in healthcare settings where robots interact with human…

Robotics · Computer Science 2021-03-29 Roya Sabbagh Novin , Amir Yazdani , Andrew Merryweather , Tucker Hermans

Prognosis on the occurrence of relapses in individuals with Relapsing-Remitting Multiple Sclerosis (RRMS), the most common subtype of Multiple Sclerosis (MS), could support individualized decisions and disease management and could be…

Machine learning systems show significant promise for forecasting patient adverse events via risk scores. However, these risk scores implicitly encode assumptions about future interventions that the patient is likely to receive, based on…