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In a multiscale modeling approach, we present computer simulation results for a rectifying bipolar nanopore on two modeling levels. In an all-atom model, we use explicit water to simulate ion transport directly with the molecular dynamics…

Mesoscale and Nanoscale Physics · Physics 2018-03-13 Zoltán Ható , Mónika Valiskó , Tamás Kristóf , Dirk Gillespie , Dezső Boda

Metal nanoparticles are receiving increased scientific attention owing to their unique physical and chemical properties that make them suitable for a wide range of applications in diverse fields, such as electrochemistry, biochemistry, and…

Chemical Physics · Physics 2020-10-09 Bendix Petersen , Rafael Roa , Joachim Dzubiella , Matej Kanduc

Ionic transport in nanopores is a fundamentally and technologically important problem in view of its occurrence in biological processes and its impact on novel DNA sequencing applications. Using microscopic calculations, here we show that…

Soft Condensed Matter · Physics 2009-09-26 Michael Zwolak , Johan Lagerqvist , Massimiliano Di Ventra

Charge regulation is a fundamental mechanism in most chemical, geochemical, and biochemical systems. Various minerals surfaces and proteins are well-known to change their charge state as a function of the activity of the hydronium ions,…

Soft Condensed Matter · Physics 2021-06-29 Martin Trulsson

It has been recently shown that a viscosity gradient could drive electrical current through a negatively charged nanochannel (Wiener and Stein, arXiv: 1807.09106). To understand the physics underlying this phenomenon, we employed the…

Fluid Dynamics · Physics 2021-11-02 Amer Alizadeh , Hirofumi Daiguji , Anne M. Benneker

We present a scaling behavior of a rectifying bipolar nanopore as a function of the parameter $\xi=R_{\mathrm{P}}/(\lambda z_{\mathrm{if}})$, where $R_{\mathrm{P}}$ is the radius of the pore, $\lambda$ is the characteristic screening length…

Mesoscale and Nanoscale Physics · Physics 2020-11-17 Dávid Fertig , Bartłomiej Matejczyk , Mónika Valiskó , Dirk Gillespie , Dezső Boda

We report a multiscale modeling study for charged cylindrical nanopores using three modeling levels that include (1) an all-atom explicit-water model studied with molecular dynamics (MD), and reduced models with implicit water containing…

Electric-field-driven electrolyte transport through nanoporous membranes is important for applications including osmotic power generation, sensing and iontronics. We derive an analytical equation in the Debye--H\"uckel regime and a…

Soft Condensed Matter · Physics 2026-05-01 Holly C. M. Baldock , David M. Huang

Characterizing the local voltage distribution within nanophysiological domains, driven by ionic currents through membrane channels, is crucial for studying cellular activity in modern biophysics, yet it presents significant experimental and…

Soft Condensed Matter · Physics 2026-05-14 Frédéric Paquin-Lefebvre , Alejandro Barea Moreno , David Holcman

In charged nanopores, ionic diffusion current reflects the ionic selectivity and ionic permeability of nanopores which determines the performance of osmotic energy conversion, i.e. the output power and efficiency. Here, theoretical…

Chemical Physics · Physics 2023-09-15 Long Ma , Zihao Gao , Jia Man , Jianyong Li , Guanghua Du , Yinghua Qiu

Short nanopores have various applications in biosensing, desalination, and energy conversion. Here, the modulation of charged exterior surfaces on ionic transport is investigated through simulations with sub-200 nm long nanopores under…

Soft Condensed Matter · Physics 2024-02-08 Long Ma , Zhe Liu , Jia Man , Jianyong Li , Zuzanna S. Siwy , Yinghua Qiu

Recent experiments with electrolytes driven through conical nanopores give evidence of strong rectified current response. In such devices, the asymmetry in the confinement is responsible of the non-Ohmic response, suggesting that the…

Mesoscale and Nanoscale Physics · Physics 2019-09-04 Sara Dal Cengio , Ignacio Pagonabarraga

Most biological molecules contain acido-basic groups that modulate their structure and interactions. A consequence is that pH gradients, local heterogeneities and dynamic variations are used by cells and organisms to drive or regulate…

Understanding over-limiting current (faster than diffusion) is a long-standing challenge in electrochemistry with applications in desalination and energy storage. Known mechanisms involve either chemical or hydrodynamic instabilities in…

Chemical Physics · Physics 2017-06-27 Ji-Hyung Han , Edwin Khoo , Peng Bai , Martin Z. Bazant

The permeation, rejection, and transport of electrolytes in water-filled nanopores are critical to ion current gating and desalinalion processes in synthetic porous membranes and the functions of biological ion channels. Mile the effects of…

Statistical Mechanics · Physics 2008-04-29 Kevin Leung

It is well-known that the swelling behavior of ionic nanogels depends on their cross-link density, however it is unclear how different topologies should affect the response of the polyelectrolyte network. Here we perform Monte Carlo…

Soft Condensed Matter · Physics 2016-03-23 Leandro G. Rizzi , Yan Levin

Continuum simulations become an important tool to uncover the mysteries in nanofluidic experiments. However, fluid flow in simulation models is usually unconsidered. Here, systematical simulations are conducted to provide a quantitative…

Chemical Physics · Physics 2024-02-08 Yinghua Qiu , Long Ma

We propose a framework to study the spatio-temporal evolution of liquid-liquid phase separation of weak polyelectrolytes in ionic solutions. Unlike strong polyelectrolytes, which carry a fixed charge, the charge state of weak…

Soft Condensed Matter · Physics 2025-03-19 Giulia Laura Celora , Ralf Blossey , Andreas Munch , Barbara Wagner

In this paper, we present a molecular theory analysis of ions and potential distribution, degree of ionization of polyelectrolyte (PE) brushes, velocity profile, volumetric flow rate, ionic selectivity, ionic conduction and advection by…

Soft Condensed Matter · Physics 2020-07-01 Milad Reshadi , Mohammad Hassan Saidi

The development of high-performance multifunctional polymer-based electronic circuits is a major step towards future flexible electronics. Here, we demonstrate a tunable approach to fabricate such devices based on rationally designed…