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Cellular behavior is governed by gene regulatory processes that are intrinsically dynamic and nonlinear, and are subject to non-negligible amounts of random fluctuations. Such conditions are ubiquitous in physical systems, where they have…

Molecular Networks · Quantitative Biology 2011-09-21 Jordi Garcia-Ojalvo

In this work, we present a computational analysis of the planar wave propagation behavior of a one-dimensional periodic multi-stable cellular material. Wave propagation in these materials is interesting because they combine the ability of…

Applied Physics · Physics 2019-11-19 Camilo Valencia , David Restrepo , Nilesh D. mankame , Pablo D. Zavattieri , Juan Gomez

Topology transcends boundaries that conventionally delineate physical, biological and engineering sciences. Our ability to mathematically describe topology, combined with our access to precision tracking and manipulation approaches, has…

Biological Physics · Physics 2021-01-01 Anupam Sengupta

This paper presents a novel approach to the description and understanding of two-dimensional binary cellular automata with the Moore neighborhood that preserve the number of active cells. Such dynamical systems are known to successfully…

Dynamical Systems · Mathematics 2025-12-10 B. Wolnik , D. M. Falkiewicz , W. Bołt , A. Rutkowski , B. De Baets

The methods of abstract simplicial homology and cohomology are reviewed and applied to the topology of electrical networks. Kirchhoffs laws of electrical circuits are shown to be manifestly homological in their origins. Since they are based…

Mathematical Physics · Physics 2019-01-11 D. H. Delphenich

The construction of a network of cell-to-cell contacts makes it possible to characterize the patterns and spatial organisation of tissues. Such networks are highly dynamic, depending on the changes of the tissue architecture caused by cell…

Tissues and Organs · Quantitative Biology 2013-06-25 Attila Csikász-Nagy , Luis M. Escudero , Martial Guillaud , Sean Sedwards , Buzz Baum , Matteo Cavaliere

A continuum model of epithelial tissue mechanics was formulated using cellular-level mechanical ingredients and cell morphogenetic processes, including cellular shape changes and cellular rearrangements. This model can include finite…

Tissues and Organs · Quantitative Biology 2017-09-06 Shuji Ishihara , Philippe Marcq , Kaoru Sugimura

The mechanical properties of cells, which influence the properties of the tissue they belong to, are controlled by various mechanisms. Bi et al. theoretically demonstrated that density-independent rigidity transition occurs in…

Soft Condensed Matter · Physics 2018-02-27 H. Nogucci

Active nematics are fluids in which the components have nematic symmetry and are driven out of equilibrium due to the microscopic generation of an active stress. When the active stress is high, it drives flows in the nematic and can lead to…

Soft Condensed Matter · Physics 2025-11-10 Daniel J. G. Pearce , Berta Martínez-Prat , Jordi Ignés-Mullol , Francesc Sagués

Systems of active particles can show a large variety of collective behavior. In theory, two aspects determine the collective behavior: the model at the particle level and the parameter regime. While many studies consider a single model and…

Soft Condensed Matter · Physics 2025-11-17 Colin-Marius Koch , Michael Wilczek

Odd elasticity encompasses active elastic systems whose stress-strain relationship is not compatible with a potential energy. As the requirement of energy conservation is lifted from linear elasticity, new anti-symmetric (odd) components…

Soft Condensed Matter · Physics 2025-07-15 Michele Fossati , Colin Scheibner , Michel Fruchart , Vincenzo Vitelli

The growth of several biological tissues is known to be controlled in part by local geometrical features, such as the curvature of the tissue interface. This control leads to changes in tissue shape that in turn can affect the tissue's…

Tissues and Organs · Quantitative Biology 2016-12-01 Almie Alias , Pascal R Buenzli

We investigate the self-organization of point-particles with short-range interactions modeled via simple 1D and 2D Hubbard-like models. We show how various properties emerge such as, boson-like ordering leading to topological structures in…

Strongly Correlated Electrons · Physics 2020-09-08 Ioannis Kleftogiannis , Ilias Amanatidis

The topological and geometrical features at the boundary zone of planar polygonal networks remain poorly understood. Based on observations and mathematical proofs, we propose that marginal cells in the thalli of Pyropia haitanensis, a…

Other Quantitative Biology · Quantitative Biology 2026-03-18 Kai Xu , Fei He

I show the assumed Bilayer structure of cell membranes is Topologically falsified by known aminophospholipid dynamics in metabolically-active, Far from Equilibrium cells. The sensitivity of lipid and cytoplasmic flows to temperature,…

Biological Physics · Physics 2011-11-09 J. T. Lofthouse

We analyze the nonlinear optics of quasi one-dimensional quantum graphs and manipulate their topology and geometry to generate for the first time nonlinearities in a simple system approaching the fundamental limits of the first and second…

Optics · Physics 2014-01-28 Rick Lytel , Shoresh Shafei , Julian H. Smith , Mark G. Kuzyk

As a method for controlling active materials, researchers have suggested designing patterns of activity on a substrate, which should guide the motion of topological defects. To investigate this concept, we model the behavior of a single…

Soft Condensed Matter · Physics 2021-02-10 Xingzhou Tang , Jonathan V. Selinger

We present a hydrodynamic theory to describe shear flows in developing epithelial tissues. We introduce hydrodynamic fields corresponding to state properties of constituent cells as well as a contribution to overall tissue shear flow due to…

Dynamics of inelastic gases are studied within the framework of random collision processes. The corresponding Boltzmann equation with uniform collision rates is solved analytically for gases, impurities, and mixtures. Generally, the energy…

Statistical Mechanics · Physics 2007-05-23 E. Ben-Naim , P. L. Krapivsky

Multicellular organisms comprise a diverse collection of stable tissues built from different cell types. It remains unclear how large numbers of interacting cells can precisely coordinate their gene expression during tissue…

Biological Physics · Physics 2022-10-31 Matthew Smart , Anton Zilman