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Most of previous image denoising methods focus on additive white Gaussian noise (AWGN). However,the real-world noisy image denoising problem with the advancing of the computer vision techiniques. In order to promote the study on this…

Computer Vision and Pattern Recognition · Computer Science 2018-04-11 Jun Xu , Hui Li , Zhetong Liang , David Zhang , Lei Zhang

This paper proposes a deep learning architecture that attains statistically significant improvements over traditional algorithms in Poisson image denoising espically when the noise is strong. Poisson noise commonly occurs in low-light and…

Computer Vision and Pattern Recognition · Computer Science 2018-09-28 Po-Yu Liu , Edmund Y. Lam

Endoscopes featuring a miniaturized design have significantly enhanced operational flexibility, portability, and diagnostic capability while substantially reducing the invasiveness of medical procedures. Recently, single-use endoscopes…

Image and Video Processing · Electrical Eng. & Systems 2025-06-19 Yu Xing , Shishi Huang , Meng Lv , Guo Chen , Huailiang Wang , Lingzhi Sui

Lacking rich and realistic data, learned single image denoising algorithms generalize poorly to real raw images that do not resemble the data used for training. Although the problem can be alleviated by the heteroscedastic Gaussian model…

Image and Video Processing · Electrical Eng. & Systems 2020-04-10 Kaixuan Wei , Ying Fu , Jiaolong Yang , Hua Huang

Fluorescence microscopy is a key driver to promote discoveries of biomedical research. However, with the limitation of microscope hardware and characteristics of the observed samples, the fluorescence microscopy images are susceptible to…

Image and Video Processing · Electrical Eng. & Systems 2022-09-15 Xuanyu Tian , Qing Wu , Hongjiang Wei , Yuyao Zhang

Fluorescence microscopy image (FMI) denoising faces critical challenges due to the compound mixed Poisson-Gaussian noise with strong spatial correlation and the impracticality of acquiring paired noisy/clean data in dynamic biomedical…

Image and Video Processing · Electrical Eng. & Systems 2025-09-25 Jizhihui Liu , Qixun Teng , Qing Ma , Junjun Jiang

Image denoising algorithms are evaluated using images corrupted by artificial noise, which may lead to incorrect conclusions about their performances on real noise. In this paper we introduce a dataset of color images corrupted by natural…

Computer Vision and Pattern Recognition · Computer Science 2018-02-06 Josue Anaya , Adrian Barbu

We extend the blindspot model for self-supervised denoising to handle Poisson-Gaussian noise and introduce an improved training scheme that avoids hyperparameters and adapts the denoiser to the test data. Self-supervised models for…

Image and Video Processing · Electrical Eng. & Systems 2020-11-20 Wesley Khademi , Sonia Rao , Clare Minnerath , Guy Hagen , Jonathan Ventura

We consider the challenging blind denoising problem for Poisson-Gaussian noise, in which no additional information about clean images or noise level parameters is available. Particularly, when only "single" noisy images are available for…

Image and Video Processing · Electrical Eng. & Systems 2021-05-25 Jaeseok Byun , Sungmin Cha , Taesup Moon

Single molecule fluorescence microscopy is a powerful technique for uncovering detailed information about biological systems, both in vitro and in vivo. In such experiments, the inherently low signal to noise ratios mean that accurate…

Computer Vision and Pattern Recognition · Computer Science 2013-06-10 Ji Won Yoon

For low-level computer vision and image processing ML tasks, training on large datasets is critical for generalization. However, the standard practice of relying on real-world images primarily from the Internet comes with image quality,…

Computer Vision and Pattern Recognition · Computer Science 2022-12-09 Gyeongmin Choe , Beibei Du , Seonghyeon Nam , Xiaoyu Xiang , Bo Zhu , Rakesh Ranjan

Denoising extreme low light images is a challenging task due to the high noise level. When the illumination is low, digital cameras increase the ISO (electronic gain) to amplify the brightness of captured data. However, this in turn…

Image and Video Processing · Electrical Eng. & Systems 2019-09-13 Hao Guan , Liu Liu , Sean Moran , Fenglong Song , Gregory Slabaugh

This study investigates the noise characteristics of intraoperative X-ray fluoroscopic images acquired during real-time image-guided radiotherapy (IGRT), and presents a novel noise image generation method based on the identified noise…

Medical Physics · Physics 2024-11-04 Yongxuan Yan , Fumitake Fujii , Takehiro Shiinoki

The prevalent convolutional neural network (CNN) based image denoising methods extract features of images to restore the clean ground truth, achieving high denoising accuracy. However, these methods may ignore the underlying distribution of…

Computer Vision and Pattern Recognition · Computer Science 2021-05-12 Yang Liu , Saeed Anwar , Zhenyue Qin , Pan Ji , Sabrina Caldwell , Tom Gedeon

The degradation of the acquired signal by Poisson noise is a common problem for various imaging applications, such as medical imaging, night vision and microscopy. Up to now, many state-of-the-art Poisson denoising techniques mainly…

Computer Vision and Pattern Recognition · Computer Science 2015-10-13 Wensen Feng , Yunjin Chen

Fluoroscopy is critical for real-time X-ray visualization in medical imaging. However, low-dose images are compromised by noise, potentially affecting diagnostic accuracy. Noise reduction is crucial for maintaining image quality, especially…

Image and Video Processing · Electrical Eng. & Systems 2024-11-05 Sun-Young Jeon , Sen Wang , Adam S. Wang , Garry E. Gold , Jang-Hwan Choi

As a hybrid imaging technology, photoacoustic microscopy (PAM) imaging suffers from noise due to the maximum permissible exposure of laser intensity, attenuation of ultrasound in the tissue, and the inherent noise of the transducer.…

Image and Video Processing · Electrical Eng. & Systems 2022-01-13 Da He , Jiasheng Zhou , Xiaoyu Shang , Jiajia Luo , Sung-Liang Chen

Modern photon-counting sensors are increasingly dominated by Poisson noise, yet conventional feature-specific imaging (FSI), based on principal component analysis (PCA), is optimized for additive Gaussian noise and variance preservation…

Optics · Physics 2026-04-20 Yizhou Lu , Andreas Velten

Image enhancement approaches often assume that the noise is signal independent, and approximate the degradation model as zero-mean additive Gaussian. However, this assumption does not hold for biomedical imaging systems where sensor-based…

Image and Video Processing · Electrical Eng. & Systems 2023-04-10 Calvin-Khang Ta , Abhishek Aich , Akash Gupta , Amit K. Roy-Chowdhury

Digital sensors can lead to noisy results under many circumstances. To be able to remove the undesired noise from images, proper noise modeling and an accurate noise parameter estimation is crucial. In this project, we use a…

Image and Video Processing · Electrical Eng. & Systems 2022-12-21 Étienne Objois , Kaan Okumuş , Nicolas Bähler
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