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This paper explores the problem of breast tissue classification of microscopy images. Based on the predominant cancer type the goal is to classify images into four categories of normal, benign, in situ carcinoma, and invasive carcinoma.…

Computer Vision and Pattern Recognition · Computer Science 2018-06-29 Kamyar Nazeri , Azad Aminpour , Mehran Ebrahimi

Image Processing represents the backbone research area within engineering and computer science specialization. It is promptly growing technologies today, and its applications founded in various aspects of biomedical fields especially in…

Image and Video Processing · Electrical Eng. & Systems 2021-11-05 Osama Rezq Shahin , Hamdy Mohammed Kelash , Gamal Mahrous Attiya , Osama Slah Farg Allah

Definitive cancer diagnosis and management depend upon the extraction of information from microscopy images by pathologists. These images contain complex information requiring time-consuming expert human interpretation that is prone to…

The surroundings of a cancerous tumor impact how it grows and develops in humans. New data from early breast cancer patients contains information on the collagen fibers surrounding the tumorous tissue -- offering hope of finding additional…

Applications · Statistics 2022-06-30 Sean Kent , Menggang Yu

The overexpression of human epidermal growth factor receptor 2 (HER2) has been established as a therapeutic target in multiple types of cancers, such as breast and gastric cancers. Immunohistochemistry (IHC) is employed as a basic HER2 test…

Image and Video Processing · Electrical Eng. & Systems 2020-09-16 Jun Zhang , Kuan Tian , Pei Dong , Haocheng Shen , Kezhou Yan , Jianhua Yao , Junzhou Huang , Xiao Han

Validation metrics are a key prerequisite for the reliable tracking of scientific progress and for deciding on the potential clinical translation of methods. While recent initiatives aim to develop comprehensive theoretical frameworks for…

With the development of digital imaging in medical microscopy, artificial intelligent-based analysis of pathological whole slide images (WSIs) provides a powerful tool for cancer diagnosis. Limited by the expensive cost of pixel-level…

Computer Vision and Pattern Recognition · Computer Science 2024-11-19 Jiawen Li , Qiehe Sun , Renao Yan , Yizhi Wang , Yuqiu Fu , Yani Wei , Tian Guan , Huijuan Shi , Yonghonghe He , Anjia Han

We present an algorithm for multi-scale tumor (chimeric cell) detection in high resolution slide scans. The broad range of tumor sizes in our dataset pose a challenge for current Convolutional Neural Networks (CNN) which often fail when…

Computer Vision and Pattern Recognition · Computer Science 2021-04-27 Qingchao Zhang , Coy D. Heldermon , Corey Toler-Franklin

Survival prediction is a critical task in pathology. In clinical practice, pathologists often examine multiple cases, leveraging a broader spectrum of cancer phenotypes to enhance pathological assessment. Despite significant advancements in…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Xinyang Li , Yi Zhang , Yi Xie , Jianfei Yang , Xi Wang , Hao Chen , Haixian Zhang

Breast cancer is one of the most prevalent cancers worldwide and pathologists are closely involved in establishing a diagnosis. Tools to assist in making a diagnosis are required to manage the increasing workload. In this context,…

Detecting cancer manually in whole slide images requires significant time and effort on the laborious process. Recent advances in whole slide image analysis have stimulated the growth and development of machine learning-based approaches…

Image and Video Processing · Electrical Eng. & Systems 2020-06-23 Sanghoon Lee , Colton Farley , Simon Shim , Yanjun Zhao , Wookjin Choi , Wook-Sung Yoo

Early detection and prognosis of breast cancer are feasible by utilizing histopathological grading of biopsy specimens. This research is focused on detection and grading of nuclear pleomorphism in histopathological images of breast cancer.…

Computer Vision and Pattern Recognition · Computer Science 2016-12-06 Pegah Faridi , Habibollah Danyali , Mohammad Sadegh Helfroush , Mojgan Akbarzadeh Jahromi

Whole slide imaging is routinely adopted for carcinoma diagnosis and prognosis. Abundant experience is required for pathologists to achieve accurate and reliable diagnostic results of whole slide images (WSI). The huge size and…

Computer Vision and Pattern Recognition · Computer Science 2024-07-09 Pingyi Chen , Chenglu Zhu , Sunyi Zheng , Honglin Li , Lin Yang

Whole Slide Images (WSI), obtained by high-resolution digital scanning of microscope slides at multiple scales, are the cornerstone of modern Digital Pathology. However, they represent a particular challenge to AI-based/AI-mediated analysis…

Computer Vision and Pattern Recognition · Computer Science 2024-04-12 Martim Afonso , Praphulla M. S. Bhawsar , Monjoy Saha , Jonas S. Almeida , Arlindo L. Oliveira

With the increase in the use of deep learning for computer-aided diagnosis in medical images, the criticism of the black-box nature of the deep learning models is also on the rise. The medical community needs interpretable models for both…

Image and Video Processing · Electrical Eng. & Systems 2020-12-21 Mookund Sureka , Abhijeet Patil , Deepak Anand , Amit Sethi

Early diagnosis of the cancer cells is necessary for making an effective treatment plan and for the health and safety of a patient. Nowadays, doctors usually use a histological grade that pathologists determine by performing a…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Varan Singh Rohila , Neeraj Lalwani , Lochan Basyal

Melanoma represents a critical health risk due to its aggressive progression and high mortality, underscoring the need for early, interpretable diagnostic tools. While deep learning has advanced in skin lesion classification, most existing…

Computer Vision and Pattern Recognition · Computer Science 2025-07-28 Ciro Listone , Aniello Murano

Manual Pap smear analysis for cervical cancer screening is limited by inter-observer variability, time constraints, and restricted expert availability. Although convolutional neural networks (CNNs) have automated cervical cell…

Computer Vision and Pattern Recognition · Computer Science 2026-05-19 Nisreen Albzour , Sarah S. Lam

Cervical cancer is a leading malignancy in female reproductive system. While AI-assisted cytology offers a cost-effective and non-invasive screening solution, current systems struggle with generalizability in complex clinical scenarios. To…

Cancer is increasingly a global health issue. Seconding cardiovascular diseases, cancers are the second biggest cause of death in the world with millions of people succumbing to the disease every year. According to the World Health…

Image and Video Processing · Electrical Eng. & Systems 2023-03-21 Bonaventure F. P. Dossou , Yenoukoume S. K. Gbenou , Miglanche Ghomsi Nono