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The heartbeat is mediated between cardiac cells by waves of electrical depolarisation. During cardiac arrhythmias, electrical activity was found to be organised in scroll waves which rotate around a dynamical filament curve. In this thesis,…

Biological Physics · Physics 2015-11-13 Hans J. F. M. Dierckx

Trapping and un-trapping of spiral tips in a two-dimensional homogeneous excitable medium with local small-world connections is studied by numerical simulation. In a homogeneous medium which can be simulated with a lattice of regular…

Pattern Formation and Solitons · Physics 2009-11-10 Xiaonan Wang , Ying Lu , Minxi Jiang , Qi Ouyang

This paper investigates the properties of unstable single-spiral wave solutions arising in the Karma model of two-dimensional cardiac tissue. In particular, we discuss how such solutions can be computed numerically on domains of arbitrary…

Pattern Formation and Solitons · Physics 2017-09-15 Christopher D. Marcotte , Roman O. Grigoriev

Developing new methods for predicting electromagnetic instabilities in cardiac activity is of primary importance. However, we still need a comprehensive view of the heart's magnetic activity at the tissue scale. To fill this gap, we present…

We investigate a system of harmonically coupled identical nonlinear constituents subject to noise in different spatial arrangements. For global coupling we find for infinitely many constituents the coexistence of several ergodic components…

adap-org · Physics 2009-10-30 R. Muller , K. Lippert , A. Kuhnel , U. Behn

Spiral waves are considered to be one of the potential mechanisms that maintains complex arrhythmias such as atrial and ventricular fibrillation. The aim of the present study was to quantify the complex dynamics of spiral waves as the…

Pattern Formation and Solitons · Physics 2018-07-03 Daniel Sohn , Konstantinos N. Aronis , Hiroshi Ashikaga

Biological systems rely on robust internal information processing: Survival depends on highly reproducible dynamics of regulatory processes. Biological information processing elements, however, are intrinsically noisy (genetic switches,…

Molecular Networks · Quantitative Biology 2009-11-10 Konstantin Klemm , Stefan Bornholdt

The dynamics of activation waves in excitable media can give rise to spiral turbulence, the resulting spatiotemporal chaos being associated with empirical biological phenomena such as life-threatening disturbances in the natural rhythm of…

Chaotic Dynamics · Physics 2008-04-07 S. Sridhar , Sitabhra Sinha

Three-dimensional excitable systems can selforganize vortex patterns that rotate around one-dimensional phase singularities called filaments. In experiments with the Belousov-Zhabotinsky reaction and numerical simulations, we pin these…

Pattern Formation and Solitons · Physics 2015-04-08 Hua Ke , Zhihui Zhang , Oliver Steinbock

In a topological dynamical system the complexity of an orbit is a measure of the amount of information (algorithmic information content) that is necessary to describe the orbit. This indicator is invariant up to topological conjugation. We…

Dynamical Systems · Mathematics 2007-05-23 Stefano Galatolo

We study the drift of spiral waves in a simple model of heterogeneous excitable medium, having gradients in local excitability or cellular coupling. For the first time, we report the anomalous drift of spiral waves towards regions having…

Pattern Formation and Solitons · Physics 2010-11-16 S. Sridhar , Sitabhra Sinha , Alexander. V. Panfilov

A new highly efficient method is developed for computation of traveling periodic waves (Stokes waves) on the free surface of deep water. A convergence of numerical approximation is determined by the complex singularites above the free…

Fluid Dynamics · Physics 2019-04-02 Pavel M. Lushnikov , Sergey A. Dyachenko , Denis A. Silantyev

Classical approaches to ecological stability rely on fully connected interaction models, yet real ecosystems are sparse and structured--a feature that qualitatively reshapes their collective dynamics. Here, we establish a thermodynamically…

Disordered Systems and Neural Networks · Physics 2025-12-30 Mattia Tarabolo , Luca Dall'Asta , Roberto Mulet

Graph Signal Processing (GSP) provides a powerful framework for analysing complex, interconnected systems by modelling data as signals on graphs. While recent advances have enabled graph topology learning from observed signals, existing…

Signal Processing · Electrical Eng. & Systems 2025-08-08 Alexander Jenkins , Thiernithi Variddhisai , Ahmed El-Medany , Fu Siong Ng , Danilo Mandic

Every sixth death in industrialised countries occurs because of cardiac arrhythmias like ventricular tachycardia (VT) and ventricular fibrillation (VF). There is growing consensus that VT is associated with an unbroken spiral wave of…

Pattern Formation and Solitons · Physics 2007-05-23 T K Shajahan , Sitabhra Sinha , Rahul Pandit

Spiral waves of excitation in cardiac tissue are associated with life-threatening cardiac arrhythmias. It is, therefore, important to study the electrophysiological factors that affect the dynamics of these spiral waves. By using an…

Biological Physics · Physics 2021-08-17 Mahesh Kumar Mulimani , Soling Zimik , Rahul Pandit

The stability of complex networks, from power grids to biological systems, is crucial for their proper functioning. It is thus important to control such systems to maintain or restore their stability. Traditional approaches rely on…

Optimization and Control · Mathematics 2025-09-23 Yuzhen Qin , Fabio Pasqualetti , Danielle S. Bassett , Marcel van Gerven

Rotors are functional reentry sources identified in clinically relevant cardiac arrhythmias, such as ventricular and atrial fibrillation. Ablation targeting rotor sites has resulted in arrhythmia termination. Recent clinical, experimental…

Tissues and Organs · Quantitative Biology 2019-03-06 Nele Vandersickel , Masaya Watanabe , Qian Tao , Jan Fostier , Katja Zeppenfeld , Alexander V Panfilov

Sustained spiral waves, also known as rotors, are pivotal mechanisms in persistent atrial fibrillation (AF). Stochasticity is inevitable in nonlinear biological systems such as the heart; however, it is unclear how noise affects the…

Biological Physics · Physics 2023-11-16 Euijun Song

The phase--space volume of regions of regular or trapped motion, for bounded or scattering systems with two degrees of freedom respectively, displays universal properties. In particular, sudden reductions in the phase-space volume or gaps…

Chaotic Dynamics · Physics 2010-10-28 L. Benet , O. Merlo