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Biological cells are able to generate intricate structures and respond to external stimuli, sculpting their membrane from within. Simplified biomimetic systems can aid in understanding the principles which govern these shape changes and…

In active matter systems, deformable boundaries provide a mechanism to organize internal active stresses and perform work on the external environment. To study a minimal model of such a system, we perform particle-based simulations of an…

Soft Condensed Matter · Physics 2022-01-05 Matthew S. E. Peterson , Aparna Baskaran , Michael F. Hagan

In recent years the functionality of synthetic active microparticles has edged even closer to that of their biological counterparts. However, we still lack the understanding needed to recreate at the microscale key features of autonomous…

Soft Condensed Matter · Physics 2024-10-28 Philipp W. A. Schönhöfer , Sharon C. Glotzer

A mechanism for self propulsion of deformable vesicle has been proposed, vesicle moves by sensing the self-generated chemical gradient. Like many molecular motors they suffer strong perturbations from the environment in which they move as a…

Biological Physics · Physics 2015-10-14 Shivam Gupta , Sreeja K. K. , Snigdha Thakur

Collections of simple, self-propelled colloidal particles exhibit complex, emergent dynamical behavior, with promising applications in microrobotics. When confined within a deformable vesicle, self-propelled rods cluster and align,…

Soft Condensed Matter · Physics 2025-10-28 Sophie Y. Lee , Philipp W. A. Schönhöfer , Sharon C. Glotzer

Eukaryote cells have a flexible shape, which dynamically changes according to the function performed by the cell. One mechanism for deforming the cell membrane into the desired shape is through the expression of curved membrane proteins.…

Biological Physics · Physics 2018-12-05 Miha Fošnarič , Samo Penič , Aleš Iglič , Veronika Kralj-Iglič , Mitja Drab , Nir Gov

Engineering synthetic materials that mimic the remarkable complexity of living organisms is a fundamental challenge in science and technology. We study the spatiotemporal patterns that emerge when an active nematicfilm of microtubules and…

Worm-like filaments that are propelled homogeneously along their tangent vector are studied by Brownian dynamics simulations. Systems in two dimensions are investigated, corresponding to filaments adsorbed to interfaces or surfaces. A large…

Soft Condensed Matter · Physics 2016-08-23 Rolf E. Isele-Holder , Jens Elgeti , Gerhard Gompper

Cellular membranes exhibit a large variety of shapes, strongly coupled to their function. Many biological processes involve dynamic reshaping of membranes, usually mediated by proteins. This interaction works both ways: while proteins…

Soft Condensed Matter · Physics 2018-06-12 Afshin Vahid , Anđela Šarić , Timon Idema

We study a generic model for the polarisation and motility of self-propelled soft objects, biological cells or biomimetic systems, interacting with a viscous substrate. The active forces generated by the cell on the substrate are modelled…

Soft Condensed Matter · Physics 2015-06-23 M. Leoni , P. Sens

A flexible membrane deforming its shape in time can self-propel in a viscous fluid. Alternatively, if the membrane is anchored, its deformation will lead to fluid transport. Past work in this area focused on situations where the deformation…

Soft Condensed Matter · Physics 2013-02-12 Arthur A. Evans , Eric Lauga

One of the most promising features of active systems is that they can extract energy from their environment and convert it to mechanical work. Self propelled particles enable rectification when in contact with rigid boundaries. They can…

Soft Condensed Matter · Physics 2022-12-13 M. C. Gandikota , A. Cacciuto

Recent experiments suggest that the interplay between cells and the mechanics of their substrate gives rise to a diversity of morphological and migrational behaviors. Here, we develop a Cellular Potts Model of polarizing cells on a…

Narrow membrane tubes are commonly pulled out from the surface of phospholipid vesicles using forces applied either through laser or magnetic tweezers or through the action of processive motor proteins. Recent examples have emerged where…

Biological Physics · Physics 2019-02-27 Gaurav Kumar , N. Ramakrishnan , Anirban Sain

We study a simple two-dimensional model for motion of an elastic filament subject to internally generated stresses and show that wave-like propagating shapes which can propel the filament can be induced by a self-organized mechanism via a…

Soft Condensed Matter · Physics 2019-08-17 S. Camalet , F. Julicher , J. Prost

How internal forces are transduced into motion through soft, fluid membranes remains a fundamental question in the study of active systems. To investigate this coupling, we develop a minimal system consisting of a single ferromagnetic…

Soft Condensed Matter · Physics 2025-07-11 Paula Magrinya , Arin Escobar Ortiz , Juan L. Aragones , Laura R. Arriaga

Natural systems integrate the work of many sub-units (cells) toward a large-scale unified goal (morphological and behavioral), which can counteract the effects of unexpected experiences, damage, or simply changes in tasks demands. In this…

The ordering of rod-like particles in soft, deformable containers emerges from the interplay of anisotropic interactions, geometric confinement, and boundary compliance. This competition couples internal particle organization to container…

Soft Condensed Matter · Physics 2026-05-22 Stijn van der Ham , André F. V. Matias , Marjolein Dijkstra , Hanumantha Rao Vutukuri

Based on symmetry consideration of migration and shape deformations, we formulate phenomenologically the dynamics of cell crawling in two dimensions. Forces are introduced to change the cell shape. The shape deformations induce migration of…

Biological Physics · Physics 2016-03-23 Takao Ohta , Mitsusuke Tarama , Masaki Sano

Flexible filaments moving in viscous fluids are ubiquitous in the natural microscopic world. For example, the swimming of bacteria and spermatozoa as well as important physiological functions at organ-level, such as the cilia-induced motion…

Soft Condensed Matter · Physics 2019-06-05 Panayiota Katsamba , Eric Lauga
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