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Nearly all cell models explicitly or implicitly deal with the biophysical constraints that must be respected for life to persist. Despite this, there is almost no systematicity in how these constraints are implemented, and we lack a…

Cell Behavior · Quantitative Biology 2026-05-20 Connor McShaffrey , Eran Agmon , Randall D. Beer

We scrutinize the temporally-resolved speed of active cargo transport in living cells, and show intermittent bursting motions. These nonlinear fluctuations follow a scaling law over several decades of time and space, the statistical…

Subcellular Processes · Quantitative Biology 2015-06-16 Bo Wang , James Kuo , Steve Granick

The dynamics of cellular pattern formation is crucial for understanding embryonic development and tissue morphogenesis. Recent studies have shown that human dermal fibroblasts cultured on liquid crystal elastomers can exhibit an increase in…

Biological Physics · Physics 2023-08-25 Mengyang Gu , Xinyi Fang , Yimin Luo

The macroscopic behaviour of active matter arises from nonequilibrium microscopic processes. In soft materials, active stresses typically drive macroscopic shape changes, which in turn alter the geometry constraining the microscopic…

Soft Condensed Matter · Physics 2024-11-26 Tim Dullweber , Roman Belousov , Anna Erzberger

Much of our mechanistic understanding of the functions of biological macromolecules is based on static structural experiments, which can be modelled either as single structures or conformational ensembles. While these provide us with…

Biomolecules · Quantitative Biology 2025-10-02 Daria Gusew , Carl G. Henning Hansen , Kresten Lindorff-Larsen

Active matter consists of self-propelled elements exhibits fascinating collective motions ranging from biological to artificial systems. Among wide varieties of active matter systems, reconstituted bio-filaments moving on molecular motor…

Soft Condensed Matter · Physics 2020-03-25 Sakurako Tanida , Ken'ya Furuta , Kaori Nishikawa , Tetsuya Hiraiwa , Hiroaki Kojima , Kazuhiro Oiwa , Masaki Sano

Active matter comprises individually driven units that convert locally stored energy into mechanical motion. Interactions between driven units lead to a variety of non-equilibrium collective phenomena in active matter. One of such phenomena…

Soft Condensed Matter · Physics 2021-06-15 Mingji Huang , Wensi Hu , Siyuan Yang , Quan-Xing Liu , H. P. Zhang

The living cell expends energetic and material resources to reliably process information from its environment. To do so, it utilises unreliable molecular circuitry that is subject to thermal and other fluctuations. Here, we argue that…

Soft Condensed Matter · Physics 2022-04-12 Kabir Husain , Sriram Ramaswamy , Madan Rao

Dense active matter, from bacterial suspensions and microtubule bundles driven by motor proteins to cellular monolayers and synthetic Janus particles, is characterised by mesoscale turbulence, the emergence of chaotic flow structures. By…

Soft Condensed Matter · Physics 2016-06-22 Sumesh P. Thampi , Amin Doostmohammadi , Tyler N. Shendruk , Ramin Golestanian , Julia M. Yeomans

Using numerical simulations, we characterized the behavior of an elastic membrane immersed in an active fluid. Our findings reveal a nontrivial folding and re-expansion of the membrane that is controlled by the interplay of its resistance…

Soft Condensed Matter · Physics 2015-07-24 S. A. Mallory , C. Valeriani , A. Cacciuto

A number of factors, such as, cell-cell interactions and self-propulsion of cells driven by cytoskeletal forces determine tissue morphologies and dynamics. To explore the interplay between these factors in controlling the dynamics at the…

Soft Condensed Matter · Physics 2025-05-12 Rajsekhar Das , Xin Li , Sumit Sinha , D. Thirumalai

There is increasing interest in the analysis of biological tissue, its organization and its dynamics with the help of mathematical models. In the ideal case emergent properties on the tissue scale can be derived from the cellular scale.…

Tissues and Organs · Quantitative Biology 2009-11-13 Tilo Beyer , Michael Meyer-Hermann

Optical solitons are self-sustained wave packets that propagate without distortion due to a balance between dispersion and nonlinearity. Their unique stability underpins key photonic applications while also playing a central role in…

Pattern Formation and Solitons · Physics 2025-12-04 François Copie , Pierre Suret , Stéphane Randoux

Active matter consumes energy from the environment and transforms it into mechanical work. Notable examples from biology include cell division, bacterial swarms, and muscle contraction. In this work, we investigate the nature of active…

Soft Condensed Matter · Physics 2023-09-28 Michael J. Landry

Active materials are capable of converting free energy into directional motion, giving rise to striking dynamical phenomena. Developing a general understanding of their structure in relation to the underlying non-equilibrium physics would…

Soft Condensed Matter · Physics 2018-10-17 Nitin Kumar , Rui Zhang , Juan J. de Pablo , Margaret L. Gardel

Collective motion of self-propelled organisms or synthetic particles often termed active fluid has attracted enormous attention in broad scientific community because of it fundamentally non-equilibrium nature. Energy input and interactions…

Soft Condensed Matter · Physics 2014-03-05 Shuang Zhou , Andrey Sokolov , Oleg D Lavrentovich , Igor S Aranson

To maintain homeostasis, living cells process information with networks of interacting molecules. Traditional models for cellular information processing have focused on networks of chemical reactions between molecules. Here, we describe how…

Biological Physics · Physics 2025-08-01 Arvind Murugan , David Zwicker , Charlotta Lorenz , Eric R. Dufresne

Living microorganisms have evolved dedicated sensory machinery to detect environmental perturbations, processing these signals through biochemical networks to guide behavior. Replicating such capabilities in synthetic active matter remains…

Soft Condensed Matter · Physics 2025-12-25 Diptabrata Paul , Nikola Milosevic , Nico Scherf , Frank Cichos

Systems driven far from equilibrium may exhibit anomalous density fluctuations: active matter with orientational order display giant density fluctuations at large scale, while systems of interacting particles close to an absorbing phase…

Statistical Mechanics · Physics 2026-03-23 Sara Dal Cengio , Romain Mari , Eric Bertin

Living organisms are molecular systems with self-sustained dynamics via energy conversion through molecular cooperation, resulting in highly complex macroscopic behaviors. Construction of such autonomous macroscopic dynamics at a molecular…