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The organization of live cells into tissues and their subsequent biological function involves inter-cell mechanical interactions, which are mediated by their elastic environment. To model this interaction, we consider cells as spherical…

Soft Condensed Matter · Physics 2024-02-20 Roman Golkov , Yair Shokef

Activity and autonomous motion are fundamental aspects of many living and engineering systems. Here, the scale of biological agents covers a wide range, from nanomotors, cytoskeleton, and cells, to insects, fish, birds, and people. Inspired…

We review recent advances in the design, synthesis, and modeling of active fluids. Active fluids have been at the center of many technological innovations and theoretical advances over the past two decades. Research on this new class of…

Soft Condensed Matter · Physics 2023-02-02 Ilham Essafri , Bappa Ghosh , Caroline Desgranges , Jerome Delhommelle

Essentially all biology is active and dynamic. Biological entities autonomously sense, com- pute, and respond using energy-coupled ratchets that can produce force and do work. The cytoskeleton, along with its associated proteins and motors,…

Soft Condensed Matter · Physics 2017-03-28 Kasimira T. Stanhope , Vikrant Yadav , Christian D. Santangelo , Jennifer L. Ross

Active networks composed of biopolymers and motor proteins provide versatile biomimetic systems that have advanced active matter physics and deepened our understanding of cytoskeletal dynamics and self-organization under diverse stimuli. In…

Boundary conditions dictate how fluids, including liquid crystals, flow when pumped through a channel. Can boundary conditions also be used to control internally driven active fluids that generate flows spontaneously? By using numerical…

Soft Condensed Matter · Physics 2022-09-13 Paarth Gulati , Suraj Shankar , M. Cristina Marchetti

Materials made from active, living, or robotic components can display emergent properties arising from local sensing and computation. Here, we realize a freestanding active metabeam with piezoelectric elements and electronic feed-forward…

Applied Physics · Physics 2021-10-14 Yangyang Chen , Xiaopeng Li , Colin Scheibner , Vincenzo Vitelli , Guoliang Huang

Engineering synthetic materials that mimic the remarkable complexity of living organisms is a fundamental challenge in science and technology. We study the spatiotemporal patterns that emerge when an active nematicfilm of microtubules and…

Emergence of regular spatial patterns is a hallmark in living matter ranging from subcellular organelles to developing embryos and to ecosystems. Mechanisms for the formation of ordered spatial patterns in biology often require chemical…

Biological Physics · Physics 2024-03-15 Haoran Xu , Yilin Wu

Cells and microorganisms employ dynamic shape changes to enable steering and avoidance for efficient spatial exploration and collective organization. In contrast, active colloids, their synthetic counterparts, currently lack similar…

Soft Condensed Matter · Physics 2025-01-03 Stefania Ketzetzi , Lorenzo Caprini , Vivien Willems , Laura Alvarez , Hartmut Löwen , Lucio Isa

Low-scattering, deep-penetration light transport in biological media remains a pivotal challenge for biophotonic technologies, including biomedical imaging, optical diagnostics, and photodynamic therapy. This review builds upon and extends…

The adaptive and surprising emergent properties of biological materials self-assembled in far-from-equilibrium environments serve as an inspiration for efforts to design nanomaterials and their properties. In particular, controlling the…

Statistical Mechanics · Physics 2023-07-07 Shriram Chennakesavalu , Sreekanth K. Manikandan , Frank Hu , Grant M. Rotskoff

Active particle systems are a class of non-equilibrium systems composed of self-propelled Brownian particles; through interactions between particles within the system, a variety of intriguing collective behaviors can emerge. Based on…

Soft Condensed Matter · Physics 2025-09-25 Sihang Guo , Guangyu Yang , Guoqing Meng , Yingying Wang , Junxing Pan , Jinjun Zhang

Cells control the size and organization of biomolecular condensates formed by liquid-liquid phase separation (LLPS), but multiple mechanisms likely contribute to this control and remain to be fully elucidated. Here we propose a…

Biological Physics · Physics 2026-04-10 Le Qiao , Peter Gispert , Lukas S. Stelzl , Friederike Schmid

The dynamic behavior of microtubules in solution can be strongly modified by interactions with walls or other structures. We examine here a microtubule growth model where the increase in size of the plus-end is perturbed by collisions with…

Soft Condensed Matter · Physics 2010-09-29 Vladimir A. Baulin , Carlos M. Marques , Fabrice Thalmann

Chemically active droplets provide simple models for cell-like systems that can grow and divide. Such active droplet systems are driven away from thermodynamic equilibrium and turn over chemically, which corresponds to a simple metabolism.…

Biological Physics · Physics 2022-09-28 Jonathan Bauermann , Christoph A. Weber , Frank Jülicher

Advanced photonic tools may enable researchers and clinicians to visualize, track, control and manipulate biological processes at the single-cell level in space and time. Biological systems are complex and highly organized on both spatial…

Optics · Physics 2021-11-30 Alina Karabchevsky , Tal Elbaz , Aviad Katiyi , Ofer Prager , Alon Friedman

Biological activity gives rise to non-equilibrium fluctuations in the cytoplasm of cells; however, there are few methods to directly measure these fluctuations. Using a reconstituted actin cytoskeleton, we show that the bending dynamics of…

Soft Condensed Matter · Physics 2009-11-13 C. P. Brangwynne , G. H. Koenderink , F. C. MacKintosh , D. A. Weitz

Biological membranes and vesicles play a central role in living systems, forming dynamic interfaces that regulate cellular organization and function. Classical descriptions of membrane mechanics that are rooted in equilibrium statistical…

Soft Condensed Matter · Physics 2026-02-24 Sreekanth Ramesh , Prashant K. Purohit , Yashashree Kulkarni

Living systems are made of active materials with microscopic components that work together to perform macroscopic biological tasks. The breakdown of these collective functionalities leads to diseases, which, conversely, could be treated by…