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Phase separation in a low-density gas-like phase and a high-density liquid-like one is a common trait of biological and synthetic self-propelling particles' systems. The competition between motility and stochastic forces is assumed to fix…

Soft Condensed Matter · Physics 2020-04-15 Pin Nie , Joyjit Chattoraj , Antonio Piscitelli , Patrick Doyle , Ran Ni , Massimo Pica Ciamarra

Because of consuming energy to drive their motion, systems of active colloids are intrinsically out of equilibrium. In the past decade, a variety of intriguing dynamic patterns have been observed in systems of active colloids, and they…

Soft Condensed Matter · Physics 2020-04-16 Zhan Ma , Mingcheng Yang , Ran Ni

Conservative and non-conservative phase-field models are considered for the numerical simulation of lateral phase separation and coarsening in biological membranes. An unfitted finite element method is devised for these models to allow for…

Numerical Analysis · Mathematics 2019-01-08 Vladimir Yushutin , Annalisa Quaini , Sheereen Majd , Maxim Olshanskii

The process of programmed cell death, namely apoptosis, is a natural mechanism that regulates healthy tissue, multicellular structures, and homeostasis. An improved understanding of apoptosis can significantly enhance our knowledge of…

Cell Behavior · Quantitative Biology 2026-03-12 Daniel A. Vaughan , Anna M. Piccinini , Mischa Zelzer , Etienne Farcot , Bindi S. Brook , Kris Van-der-Zee , Luis Espath

Bacteria commonly live in structured communities that affect human health and influence ecological systems. Heterogeneous populations, such as motile and non-motile populations, often coexist in bacteria communities. Motile subpopulations…

Biological Physics · Physics 2019-06-19 Haoran Xu , Justas Dauparas , Debasish Das , Eric Lauga , Yilin Wu

Differences in activities in colloidal particles are sufficient to drive phase separation between active and passive (or less active) particles, even if they have only excluded volume interactions. In this paper, we study the phase…

Soft Condensed Matter · Physics 2020-05-27 Efe Ilker , Jean-François Joanny

The interaction of phase-separating systems with chemical reactions is of great interest in various contexts, from biology to material science. In biology, phase separation is thought to be the driving force behind the formation of…

Soft Condensed Matter · Physics 2026-01-08 Franco Blanchini , Elisa Franco , Giulia Giordano , Dino Osmanovic

Partitioning of (bio)materials in polymeric mixtures is a key phenomenon both in cellular environments, as well as in industrial applications. In cells, several macromolecules are suspended within different biomolecular phases. On the other…

Soft Condensed Matter · Physics 2025-10-15 Vikki Anand Varma , Alberto Scacchi

A series of simulations aimed at elucidating the self-assembly dynamics of spherical virus capsids is described. This little-understood phenomenon is a fascinating example of the complex processes that occur in the simplest of organisms.…

Soft Condensed Matter · Physics 2015-05-19 D. C. Rapaport

In this review, we discuss modularity and hierarchy in biological systems. We review examples from protein structure, genetics, and biological networks of modular partitioning of the geometry of biological space. We review theories to…

Populations and Evolution · Quantitative Biology 2015-06-04 Dirk M. Lorenz , Alice Jeng , Michael W. Deem

The present view of biological phenomena is based on a biochemical paradigm that development of living organisms is defined by information stored in a molecular form as some genetic code. However, new discoveries indicate that biological…

Other Quantitative Biology · Quantitative Biology 2023-11-14 Yuri K. Shestopaloff

The growth, form, and division of prebiotic vesicles, membraneous bags of fluid of varying components and shapes is hypothesized to have served as the substrate for the origin of life. The dynamics of these out-of-equilibrium structures is…

Soft Condensed Matter · Physics 2019-07-24 Teresa Ruiz-Herrero , Thomas G. Fai , L. Mahadevan

This article presents a physical biology approach to understanding organization and segregation of bacterial chromosomes. The author uses a "piston" analogy for bacterial chromosomes in a cell, which leads to a phase diagram for the…

Subcellular Processes · Quantitative Biology 2010-06-01 Suckjoon Jun

We consider a phase-separating mixture of active and passive fluids and explore morphological asymmetries of the emerging dominantly bicontinous dynamic emulsion. Two-dimensional numerical simulations reveal that the geometric and…

Soft Condensed Matter · Physics 2026-01-22 Rainer Backofen , Axel Voigt

Many biological processes can be thought of as the result of an underlying dynamics in which the system repeatedly undergoes distinct and abortive trajectories with the dynamical process only ending when some specific process, purpose,…

Biological Physics · Physics 2025-06-05 Jane Kondev , Marc Kirschner , Hernan G. Garcia , Gabriel L. Salmon , Rob Phillips

At the heart of many contemporary theories of life is the concept of biological self-organisation: organisms have to continuously produce and maintain the conditions of their own existence in order to stay alive. The way in which these…

Quantitative Methods · Quantitative Biology 2025-03-17 Emmy Brown , Sean T. Vittadello

The biological cell exhibits a fantastic range of behaviors, but ultimately these are governed by a handful of physical and chemical principles. Here we explore simple theory, known for decades and based on the simple thermodynamics of…

Biomolecules · Quantitative Biology 2020-03-25 Daniel M. Zuckerman

Phase separation can drive spatial organization of multicomponent mixtures. For instance in developing animal embryos, effective phase separation descriptions have been used to account for the spatial organization of different tissue types.…

Soft Condensed Matter · Physics 2023-01-18 Simon Gsell , Matthias Merkel

Tailoring the nanomorphology of organic photoactive layers through a specialized chain of processing steps is an imperative challenge on the path towards reliable and performant organic electronic manufacturing. This hurdle generally proves…

Materials Science · Physics 2025-12-19 Maxime Siber , Olivier J. J. Ronsin , Gitti L. Frey , Jens Harting

Collective motion is a phenomenon observed across length scales in nature, from bacterial swarming and tissue migration to the flocking of animals. The mechanisms underlying this behavior vary significantly depending on the biological…

Soft Condensed Matter · Physics 2025-01-15 Urvi Mahendra Bora , Mohd Suhail Rizvi
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