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For effective treatment of Alzheimer disease (AD), it is important to identify subjects who are most likely to exhibit rapid cognitive decline. Herein, we developed a novel framework based on a deep convolutional neural network which can…

Computer Vision and Pattern Recognition · Computer Science 2017-04-21 Hongyoon Choi , Kyong Hwan Jin

We present a theoretical study of continual and experiential learning in large language model agents that combine episodic memory with reinforcement learning. We argue that the key mechanism for continual adaptation, without updating model…

Artificial Intelligence · Computer Science 2026-01-30 Jun Wang

Alzheimer's disease (AD) is a neurodegenerative disorder that is beginning with amyloidosis, followed by neuronal loss and deterioration in structure, function, and cognition. The accumulation of amyloid-beta in the brain, measured through…

The early detection of Alzheimer's disease (AD) requires an understanding of the relationships between a wide range of features. Conditional independencies and partial correlations are suitable measures for these relationships, because they…

Applications · Statistics 2025-01-22 Lucas Vogels , Reza Mohammadi , Marit Schoonhoven , S. Ilker Birbil , Martin Dyrba

Dementia is a syndrome characterised by the decline of different cognitive abilities. Alzheimer's Disease (AD) is the most common dementia affecting cognitive domains such as memory and learning, perceptual-motion or executive function.…

Computer Vision and Pattern Recognition · Computer Science 2018-10-26 Juan Manuel Fernández Montenegro

The ability to accurately detect onset of dementia is important in the treatment of the disease. Clinically, the diagnosis of Alzheimer Disease (AD) and Mild Cognitive Impairment (MCI) patients are based on an integrated assessment of…

Signal Processing · Electrical Eng. & Systems 2022-11-18 Wan-Ting Hsieh , Jeremy Lefort-Besnard , Hao-Chun Yang , Li-Wei Kuo , Chi-Chun Lee

Episodic memory plays an important role in the behavior of animals and humans. It allows the accumulation of information about current state of the environment in a task-agnostic way. This episodic representation can be later accessed by…

Neural and Evolutionary Computing · Computer Science 2019-05-08 Artyom Y. Sorokin , Mikhail S. Burtsev

Background: Impairment of visual spatial cognitive function is the most common early clinical manifestation of Alzheimer's Disease (AD). When the Montreal Cognitive Assessment (MoCA) uses the "0/1" binary method ("pass/fail") to evaluate…

Associative memory or content addressable memory is an important component function in computer science and information processing and is a key concept in cognitive and computational brain science. Many different neural network…

Neural and Evolutionary Computing · Computer Science 2025-02-19 Anders Lansner , Naresh B Ravichandran , Pawel Herman

Memristive associative learning has gained significant attention for its ability to mimic fundamental biological learning mechanisms while maintaining system simplicity. In this work, we introduce a high-order memristive associative…

Neural and Evolutionary Computing · Computer Science 2024-10-23 Shengbo Wang , Xuemeng Li , Jialin Ding , Weihao Ma , Ying Wang , Luigi Occhipinti , Arokia Nathan , Shuo Gao

For dementia screening and monitoring, standardized tests play a key role in clinical routine since they aim at minimizing subjectivity by measuring performance on a variety of cognitive tasks. In this paper, we report on a study that…

Audio and Speech Processing · Electrical Eng. & Systems 2022-06-14 Franziska Braun , Markus Förstel , Bastian Oppermann , Andreas Erzigkeit , Thomas Hillemacher , Hartmut Lehfeld , Korbinian Riedhammer

{Introduction: } Dementia is a neurological disorder associated with aging that can cause a loss of cognitive functions, impacting daily life. Alzheimer's disease (AD) is the most common cause of dementia, accounting for 50--70\% of cases,…

Neurons and Cognition · Quantitative Biology 2023-11-07 Zaineb Ajra , Binbin Xu , Gérard Dray , Jacky Montmain , Stéphane Perrey

Associative memories are structures that store data in such a way that it can later be retrieved given only a part of its content -- a sort-of error/erasure-resilience property. They are used in applications ranging from caches and memory…

Information Theory · Computer Science 2013-04-23 Vincent Gripon , Michael Rabbat

Functional neuroimaging can measure the brain?s response to an external stimulus. It is used to perform brain mapping: identifying from these observations the brain regions involved. This problem can be cast into a linear supervised…

Machine Learning · Computer Science 2012-07-03 Gael Varoquaux , Alexandre Gramfort , Bertrand Thirion

Our ability to track multiple objects in a dynamic environment enables us to perform everyday tasks such as driving, playing team sports, and walking in a crowded mall. Despite more than three decades of literature on multiple object…

Neurons and Cognition · Quantitative Biology 2022-08-01 Yannick Roy , Jocelyn Faubert

This paper studies the error metric selection for long-term memory learning in sequence modelling. We examine the bias towards short-term memory in commonly used errors, including mean absolute/squared error. Our findings show that all…

Machine Learning · Computer Science 2023-07-24 Shida Wang , Zhanglu Yan

We describe a method for the neural decoding of memory from EEG data. Using this method, a concept being recalled can be identified from an EEG trace with an average top-1 accuracy of about 78.4% (chance 4%). The method employs deep…

Machine Learning · Computer Science 2023-08-08 Glenn Bruns , Michael Haidar , Federico Rubino

Heretofore, neural networks with external memory are restricted to single memory with lossy representations of memory interactions. A rich representation of relationships between memory pieces urges a high-order and segregated relational…

Machine Learning · Computer Science 2020-06-12 Hung Le , Truyen Tran , Svetha Venkatesh

Most approaches to machine learning from electronic health data can only predict a single endpoint. Here, we present an alternative that uses unsupervised deep learning to simulate detailed patient trajectories. We use data comprising…

Machine Learning · Computer Science 2019-10-10 Charles K. Fisher , Aaron M. Smith , Jonathan R. Walsh , the Coalition Against Major Diseases

Alzheimer's disease (AD) constitutes a complex neurocognitive disease and is the main cause of dementia. Although many studies have been proposed targeting at diagnosing dementia through spontaneous speech, there are still limitations.…

Computation and Language · Computer Science 2023-08-24 Loukas Ilias , Dimitris Askounis
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