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Deep learning has shown great promise in the ability to automatically annotate organs in magnetic resonance imaging (MRI) scans, for example, of the brain. However, despite advancements in the field, the ability to accurately segment…

Image and Video Processing · Electrical Eng. & Systems 2024-03-26 Cosmin Ciausu , Deepa Krishnaswamy , Benjamin Billot , Steve Pieper , Ron Kikinis , Andrey Fedorov

Recent advances in vision-language models (VLMs) have shown remarkable potential in bridging visual and textual modalities. In computational pathology, domain-specific VLMs, which are pre-trained on extensive histopathology image-text…

Computer Vision and Pattern Recognition · Computer Science 2025-03-03 Anh Tien Nguyen , Keunho Byeon , Kyungeun Kim , Jin Tae Kwak

Deep learning has revolutionized the accurate segmentation of diseases in medical imaging. However, achieving such results requires training with numerous manual voxel annotations. This requirement presents a challenge for whole-body…

Image and Video Processing · Electrical Eng. & Systems 2023-11-27 Matthias Hadlich , Zdravko Marinov , Moon Kim , Enrico Nasca , Jens Kleesiek , Rainer Stiefelhagen

Cancer subtyping is one of the most challenging tasks in digital pathology, where Multiple Instance Learning (MIL) by processing gigapixel whole slide images (WSIs) has been in the spotlight of recent research. However, MIL approaches do…

Precise identification of multiple cell classes in high-resolution Giga-pixel whole slide imaging (WSI) is critical for various clinical scenarios. Building an AI model for this purpose typically requires pixel-level annotations, which are…

Image and Video Processing · Electrical Eng. & Systems 2023-08-14 Xueyuan Li , Ruining Deng , Yucheng Tang , Shunxing Bao , Haichun Yang , Yuankai Huo

In interventional radiology, short video sequences of vein structure in motion are captured in order to help medical personnel identify vascular issues or plan intervention. Semantic segmentation can greatly improve the usefulness of these…

Computer Vision and Pattern Recognition · Computer Science 2018-08-06 Athanasios Vlontzos , Krystian Mikolajczyk

Histopathology whole slide images (WSIs) are being widely used to develop deep learning-based diagnostic solutions, especially for precision oncology. Most of these diagnostic softwares are vulnerable to biases and impurities in the…

Image and Video Processing · Electrical Eng. & Systems 2024-10-01 Abhijeet Patil , Harsh Diwakar , Jay Sawant , Nikhil Cherian Kurian , Subhash Yadav , Swapnil Rane , Tripti Bameta , Amit Sethi

Manual annotation of medical images is highly subjective, leading to inevitable and huge annotation biases. Deep learning models may surpass human performance on a variety of tasks, but they may also mimic or amplify these biases. Although…

Computer Vision and Pattern Recognition · Computer Science 2022-03-23 Zehui Liao , Shishuai Hu , Yutong Xie , Yong Xia

We present an interactive approach to train a deep neural network pixel classifier for the segmentation of neuronal structures. An interactive training scheme reduces the extremely tedious manual annotation task that is typically required…

Computer Vision and Pattern Recognition · Computer Science 2016-10-31 Felix Gonda , Verena Kaynig , Ray Thouis , Daniel Haehn , Jeff Lichtman , Toufiq Parag , Hanspeter Pfister

Learning good representation of giga-pixel level whole slide pathology images (WSI) for downstream tasks is critical. Previous studies employ multiple instance learning (MIL) to represent WSIs as bags of sampled patches because, for most…

Computer Vision and Pattern Recognition · Computer Science 2022-12-01 Chunyuan Li , Xinliang Zhu , Jiawen Yao , Junzhou Huang

Most medical image lesion segmentation methods rely on hand-crafted accurate annotations of the original image for supervised learning. Recently, a series of weakly supervised or unsupervised methods have been proposed to reduce the…

Computer Vision and Pattern Recognition · Computer Science 2024-06-24 Jiawei Chen , Dingkang Yang , Yuxuan Lei , Lihua Zhang

Objective: This article presents an automatic image processing framework to extract quantitative high-level information describing the micro-environment of glomeruli in consecutive whole slide images (WSIs) processed with different staining…

Computer Vision and Pattern Recognition · Computer Science 2021-05-04 Odyssee Merveille , Thomas Lampert , Jessica Schmitz , Germain Forestier , Friedrich Feuerhake , Cédric Wemmert

Deep neural networks (DNNs) have achieved great success in a wide variety of medical image analysis tasks. However, these achievements indispensably rely on the accurately-annotated datasets. If with the noisy-labeled images, the training…

Computer Vision and Pattern Recognition · Computer Science 2019-01-25 Cheng Xue , Qi Dou , Xueying Shi , Hao Chen , Pheng Ann Heng

Accurate classification of Whole Slide Images (WSIs) and Regions of Interest (ROIs) is a fundamental challenge in computational pathology. While mainstream approaches often adopt Multiple Instance Learning (MIL), they struggle to capture…

Computer Vision and Pattern Recognition · Computer Science 2025-08-08 Mingxi Fu , Xitong Ling , Yuxuan Chen , Jiawen Li , fanglei fu , Huaitian Yuan , Tian Guan , Yonghong He , Lianghui Zhu

Background: Accurate segmentation of microscopic structures such as bio-artificial capsules in microscopy imaging is a prerequisite to the computer-aided understanding of important biomechanical phenomenons. State-of-the-art segmentation…

Computer Vision and Pattern Recognition · Computer Science 2023-01-10 Arnaud Deleruyelle , Cristian Versari , John Klein

Digital gigapixel whole slide image (WSI) is widely used in clinical diagnosis, and automated WSI analysis is key for computer-aided diagnosis. Currently, analyzing the integrated descriptor of probabilities or feature maps from massive…

Computer Vision and Pattern Recognition · Computer Science 2022-06-06 Ziquan Wei , Shenghua Cheng , Junbo Hu , Li Chen , Shaoqun Zeng , Xiuli Liu

Microscopic interpretation of histopathology images underlies many important diagnostic and treatment decisions. While advances in vision-language modeling raise new opportunities for analysis of such images, the gigapixel-scale size of…

Partial nephrectomy (PN) is common surgery in urology. Digitization of renal anatomies brings much help to many computer-aided diagnosis (CAD) techniques during PN. However, the manual delineation of kidney vascular system and tumor on each…

Image and Video Processing · Electrical Eng. & Systems 2023-05-24 Nan Ma , Ying Yang , Dongkai Zhou

This work studies semantic segmentation using 3D LiDAR data. Popular deep learning methods applied for this task require a large number of manual annotations to train the parameters. We propose a new method that makes full use of the…

Robotics · Computer Science 2019-05-24 Jilin Mei , Huijing Zhao

Nanoparticles occur in various environments as a consequence of man-made processes, which raises concerns about their impact on the environment and human health. To allow for proper risk assessment, a precise and statistically relevant…