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This paper introduces a network for volumetric segmentation that learns from sparsely annotated volumetric images. We outline two attractive use cases of this method: (1) In a semi-automated setup, the user annotates some slices in the…

Computer Vision and Pattern Recognition · Computer Science 2016-06-22 Özgün Çiçek , Ahmed Abdulkadir , Soeren S. Lienkamp , Thomas Brox , Olaf Ronneberger

In pre-clinical pathology, there is a paradox between the abundance of raw data (whole slide images from many organs of many individual animals) and the lack of pixel-level slide annotations done by pathologists. Due to time constraints and…

Computer Vision and Pattern Recognition · Computer Science 2023-02-06 Marco Bertolini , Van-Khoa Le , Jake Pencharz , Andreas Poehlmann , Djork-Arné Clevert , Santiago Villalba , Floriane Montanari

Nuclei segmentation is one of the important tasks for whole slide image analysis in digital pathology. With the drastic advance of deep learning, recent deep networks have demonstrated successful performance of the nuclei segmentation task.…

Computer Vision and Pattern Recognition · Computer Science 2019-07-23 Inwan Yoo , Donggeun Yoo , Kyunghyun Paeng

Considering the profound transformation affecting pathology practice, we aimed to develop a scalable artificial intelligence (AI) system to diagnose colorectal cancer from whole-slide images (WSI). For this, we propose a deep learning (DL)…

Segmentation is essential for medical image analysis tasks such as intervention planning, therapy guidance, diagnosis, treatment decisions. Deep learning is becoming increasingly prominent for segmentation, where the lack of annotations,…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Firat Ozdemir , Zixuan Peng , Christine Tanner , Philipp Fuernstahl , Orcun Goksel

Multiple Instance Learning (MIL) has been widely applied in histopathology to classify Whole Slide Images (WSIs) with slide-level diagnoses. While the ground truth is established by expert pathologists, the slides can be difficult to…

Computer Vision and Pattern Recognition · Computer Science 2026-03-11 Marie Arrivat , Rémy Peyret , Elsa Angelini , Pietro Gori

Automatic medical image segmentation plays a critical role in scientific research and medical care. Existing high-performance deep learning methods typically rely on large training datasets with high-quality manual annotations, which are…

Image and Video Processing · Electrical Eng. & Systems 2021-11-17 Shanshan Wang , Cheng Li , Rongpin Wang , Zaiyi Liu , Meiyun Wang , Hongna Tan , Yaping Wu , Xinfeng Liu , Hui Sun , Rui Yang , Xin Liu , Jie Chen , Huihui Zhou , Ismail Ben Ayed , Hairong Zheng

Manual annotation of medical images is a labor-intensive and time-consuming process, posing a significant bottleneck in the development and deployment of robust medical imaging AI systems. This paper introduces a novel hands-free Human-AI…

Image and Video Processing · Electrical Eng. & Systems 2025-07-29 Yizhe Zhang

The splendid success of convolutional neural networks (CNNs) in computer vision is largely attributable to the availability of massive annotated datasets, such as ImageNet and Places. However, in medical imaging, it is challenging to create…

Machine Learning · Computer Science 2021-04-13 Zongwei Zhou , Jae Y. Shin , Suryakanth R. Gurudu , Michael B. Gotway , Jianming Liang

The need for labour intensive pixel-wise annotation is a major limitation of many fully supervised learning methods for segmenting bioimages that can contain numerous object instances with thin separations. In this paper, we introduce a…

Computer Vision and Pattern Recognition · Computer Science 2020-09-11 Rihuan Ke , Aurélie Bugeau , Nicolas Papadakis , Peter Schuetz , Carola-Bibiane Schönlieb

Image segmentation and classification are the two main fundamental steps in pattern recognition. To perform medical image segmentation or classification with deep learning models, it requires training on large image dataset with annotation.…

Computer Vision and Pattern Recognition · Computer Science 2020-01-17 Anandhanarayanan Kamalakannan , Shiva Shankar Ganesan , Govindaraj Rajamanickam

Instance segmentation is a computer vision task where separate objects in an image are detected and segmented. State-of-the-art deep neural network models require large amounts of labeled data in order to perform well in this task. Making…

Computer Vision and Pattern Recognition · Computer Science 2022-02-21 Tuomas Sormunen , Arttu Lämsä , Miguel Bordallo Lopez

Deep learning methods are widely used for medical applications to assist medical doctors in their daily routines. While performances reach expert's level, interpretability (highlight how and what a trained model learned and why it makes a…

Computer Vision and Pattern Recognition · Computer Science 2020-09-30 Antoine Pirovano , Hippolyte Heuberger , Sylvain Berlemont , Saïd Ladjal , Isabelle Bloch

Whole-slide image (WSI) classification is a challenging task because 1) patches from WSI lack annotation, and 2) WSI possesses unnecessary variability, e.g., stain protocol. Recently, Multiple-Instance Learning (MIL) has made significant…

Computer Vision and Pattern Recognition · Computer Science 2025-08-12 Joohyung Lee , Heejeong Nam , Kwanhyung Lee , Sangchul Hahn

The process of annotating histological gigapixel-sized whole slide images (WSIs) at the pixel level for the purpose of training a supervised segmentation model is time-consuming. Region-based active learning (AL) involves training the model…

Computer Vision and Pattern Recognition · Computer Science 2023-07-17 Jingna Qiu , Frauke Wilm , Mathias Öttl , Maja Schlereth , Chang Liu , Tobias Heimann , Marc Aubreville , Katharina Breininger

Surgical tool segmentation in endoscopic images is an important problem: it is a crucial step towards full instrument pose estimation and it is used for integration of pre- and intra-operative images into the endoscopic view. While many…

Computer Vision and Pattern Recognition · Computer Science 2020-07-10 Daniil Pakhomov , Wei Shen , Nassir Navab

Continual learning is rapidly emerging as a key focus in computer vision, aiming to develop AI systems capable of continuous improvement, thereby enhancing their value and practicality in diverse real-world applications. In healthcare,…

Medical image segmentation is a fundamental and critical step in many image-guided clinical approaches. Recent success of deep learning-based segmentation methods usually relies on a large amount of labeled data, which is particularly…

Computer Vision and Pattern Recognition · Computer Science 2023-11-15 Rushi Jiao , Yichi Zhang , Le Ding , Rong Cai , Jicong Zhang

We aim at segmenting small organs (e.g., the pancreas) from abdominal CT scans. As the target often occupies a relatively small region in the input image, deep neural networks can be easily confused by the complex and variable background.…

Computer Vision and Pattern Recognition · Computer Science 2018-04-10 Qihang Yu , Lingxi Xie , Yan Wang , Yuyin Zhou , Elliot K. Fishman , Alan L. Yuille

The medical imaging literature has witnessed remarkable progress in high-performing segmentation models based on convolutional neural networks. Despite the new performance highs, the recent advanced segmentation models still require large,…

Image and Video Processing · Electrical Eng. & Systems 2020-02-13 Nima Tajbakhsh , Laura Jeyaseelan , Qian Li , Jeffrey Chiang , Zhihao Wu , Xiaowei Ding