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To analyze high-dimensional and complex data in the real world, deep generative models, such as variational autoencoder (VAE) embed data in a low-dimensional space (latent space) and learn a probabilistic model in the latent space. However,…

Machine Learning · Computer Science 2020-09-01 Keizo Kato , Jing Zhou , Tomotake Sasaki , Akira Nakagawa

In this paper, we advocate the adoption of metric preservation as a powerful prior for learning latent representations of deformable 3D shapes. Key to our construction is the introduction of a geometric distortion criterion, defined…

Machine Learning · Computer Science 2020-12-14 Luca Cosmo , Antonio Norelli , Oshri Halimi , Ron Kimmel , Emanuele Rodolà

As a widely recognized approach to deep generative modeling, Variational Auto-Encoders (VAEs) still face challenges with the quality of generated images, often presenting noticeable blurriness. This issue stems from the unrealistic…

Machine Learning · Computer Science 2023-05-22 Georgios Batzolis , Jan Stanczuk , Carola-Bibiane Schönlieb

Regular mammography screening is crucial for early breast cancer detection. By leveraging deep learning-based risk models, screening intervals can be personalized, especially for high-risk individuals. While recent methods increasingly…

Computer Vision and Pattern Recognition · Computer Science 2025-11-12 Solveig Thrun , Stine Hansen , Zijun Sun , Nele Blum , Suaiba A. Salahuddin , Xin Wang , Kristoffer Wickstrøm , Elisabeth Wetzer , Robert Jenssen , Maik Stille , Michael Kampffmeyer

We present deformable unsupervised medical image registration using a randomly-initialized deep convolutional neural network (CNN) as regularization prior. Conventional registration methods predict a transformation by minimizing…

Image and Video Processing · Electrical Eng. & Systems 2019-08-05 Max-Heinrich Laves , Sontje Ihler , Tobias Ortmaier

Diffeomorphic registration frameworks such as Large Deformation Diffeomorphic Metric Mapping (LDDMM) are used in computer graphics and the medical domain for atlas building, statistical latent modeling, and pairwise and groupwise…

Image and Video Processing · Electrical Eng. & Systems 2024-07-31 Sven Dummer , Nicola Strisciuglio , Christoph Brune

The ability to accurately model random fields plays a critical role in science and engineering for problems involving uncertain, spatially-varying quantities such as heterogeneous material properties and turbulent flows. Deep generative…

Diffusion probabilistic models have been shown to generate state-of-the-art results on several competitive image synthesis benchmarks but lack a low-dimensional, interpretable latent space, and are slow at generation. On the other hand,…

Machine Learning · Computer Science 2022-11-30 Kushagra Pandey , Avideep Mukherjee , Piyush Rai , Abhishek Kumar

In data-driven drug discovery, designing molecular descriptors is a very important task. Deep generative models such as variational autoencoders (VAEs) offer a potential solution by designing descriptors as probabilistic latent vectors…

Machine Learning · Computer Science 2023-08-23 Daiki Koge , Naoaki Ono , Shigehiko Kanaya

Deformable registration of two-dimensional/three-dimensional (2D/3D) images of abdominal organs is a complicated task because the abdominal organs deform significantly and their contours are not detected in two-dimensional X-ray images. We…

Image and Video Processing · Electrical Eng. & Systems 2022-12-13 Ryuto Miura , Megumi Nakao , Mitsuhiro Nakamura , Tetsuya Matsuda

One aim of dimensionality reduction is to discover the main factors that explain the data, and as such is paramount to many applications. When working with high dimensional data, autoencoders offer a simple yet effective approach to learn…

Machine Learning · Computer Science 2025-08-29 Benjamin Couéraud , Vikram Sunkara , Christof Schütte

The correlation of optical measurements with a correct pathology label is often hampered by imprecise registration caused by deformations in histology images. This study explores an automated multi-modal image registration technique…

Image and Video Processing · Electrical Eng. & Systems 2023-11-27 Lianne Feenstra , Maud Lambregts , Theo J. M Ruers , Behdad Dashtbozorg

Among applications of deep learning (DL) involving low cost sensors, remote image classification involves a physical channel that separates edge sensors and cloud classifiers. Traditional DL models must be divided between an encoder for the…

Image and Video Processing · Electrical Eng. & Systems 2023-10-31 Siyu Qi , Achintha Wijesinghe , Lahiru D. Chamain , Zhi Ding

Deformable image registration is a very important field of research in medical imaging. Recently multiple deep learning approaches were published in this area showing promising results. However, drawbacks of deep learning methods are the…

Computer Vision and Pattern Recognition · Computer Science 2020-02-11 Tobias Fechter , Dimos Baltas

The high-dimensional nature of the 4-D light field (LF) poses great challenges in achieving efficient and effective feature embedding, that severely impacts the performance of downstream tasks. To tackle this crucial issue, in contrast to…

Image and Video Processing · Electrical Eng. & Systems 2024-01-12 Xianqiang Lyu , Junhui Hou

Medical image registration is one of the key processing steps for biomedical image analysis such as cancer diagnosis. Recently, deep learning based supervised and unsupervised image registration methods have been extensively studied due to…

Computer Vision and Pattern Recognition · Computer Science 2019-07-03 Boah Kim , Jieun Kim , June-Goo Lee , Dong Hwan Kim , Seong Ho Park , Jong Chul Ye

Disentangled representations enable models to separate factors of variation that are shared across experimental conditions from those that are condition-specific. This separation is essential in domains such as biomedical data analysis,…

Machine Learning · Computer Science 2025-12-16 Yuli Slavutsky , Ozgur Beker , David Blei , Bianca Dumitrascu

The paper adapts the large deformation diffeomorphic metric mapping framework for image registration to the indirect setting where a template is registered against a target that is given through indirect noisy observations. The registration…

Numerical Analysis · Mathematics 2019-11-06 Chong Chen , Ozan Öktem

Variational autoencoders employ an encoding neural network to generate a probabilistic representation of a data set within a low-dimensional space of latent variables followed by a decoding stage that maps the latent variables back to the…

Statistical Mechanics · Physics 2022-04-13 David Yevick

Temporal volume images with 3D+t (4D) information are often used in medical imaging to statistically analyze temporal dynamics or capture disease progression. Although deep-learning-based generative models for natural images have been…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Boah Kim , Jong Chul Ye