English
Related papers

Related papers: Resolving dynamics and function of transient state…

200 papers

A ubiquitous building block of signaling pathways is a cycle of covalent modification (e.g., phosphorylation and dephosphorylation in MAPK cascades). Our paper explores the kind of information processing and filtering that can be…

Molecular Networks · Quantitative Biology 2015-05-13 Carlos Gomez-Uribe , George C. Verghese , Leonid A. Mirny

RAndom Temporal Signals (RATS) method has proven to be a useful and versatile method for measuring photoluminescence (PL) dynamics and fluorescence lifetime imaging (FLIM). Here, we present two fundamental development steps in the method.…

Optics · Physics 2023-02-15 Jiri Junek , Karel Zidek

A protein undergoes conformational dynamics with multiple time scales, which results in fluctuating enzyme activities. Recent studies in single molecule enzymology have observe this "age-old" dynamic disorder phenomenon directly. However,…

Biomolecules · Quantitative Biology 2009-11-10 Zhanghan Wu , Vlad Elgart , Hong Qian , Jianhua Xing

Modeling microstructural evolution at large strains requires mechanical formulations that remain thermodynamically consistent while capturing significant lattice rotations and transformation-induced stresses. However, most existing…

Materials Science · Physics 2025-11-21 Tushar Jogi

We obtain the phase diagram for a harmonically trapped dilute dipolar condensate with a short ranged conservative three-body interaction. We show that this system supports two distinct fluid states: a usual condensate state and a…

Quantum Gases · Physics 2016-03-30 P. B. Blakie

A method is presented that, when used in conjunction with single molecule experimental techniques, allows for the extraction of rates and mechanical properties of a biomolecule undergoing transitions between mechanically distinct states.…

Biomolecules · Quantitative Biology 2009-09-29 Darren E. Segall

Solid-state emitters with atom-like optical and magnetic transitions are highly desirable for efficient and scalable quantum state engineering and information processing. Quantum dots, color centers and impurities embedded in inorganic…

In Fermionic Molecular Dynamics the occurrence of multifragmentation depends strongly on the intrinsic structure of the many-body state. Slater determinants with narrow single-particle states and a cluster substructure show…

Nuclear Theory · Physics 2007-05-23 T. Neff , H. Feldmeier , R. Roth , J. Schnack

We study dynamical phase transitions in a model supercooled liquid. These transitions occur in ensembles of trajectories that are biased towards low (or high) dynamical activity. We compare two different measures of activity that were…

Statistical Mechanics · Physics 2015-06-15 Christopher J. Fullerton , Robert L. Jack

We have performed a structural analysis of the Ni K-edge XANES spectrum of a square planar coordination complex, Ni-tetramesitylporphyrin, Ni(II)TMP, in dilute toluene solution. The fit of the spectrum was carried out in the frame of the…

Materials Science · Physics 2008-03-14 S. Della Longa , L. X. Chen , P. Frank , K. Hayakawa , K. Hatada , M. Benfatto

Clarifying electronic and vibronic properties at individual molecule level provides key insights to future chemistry, nanoelectronics, and quantum information technologies. The single electron tunneling spectroscopy has been used to study…

Mesoscale and Nanoscale Physics · Physics 2018-09-05 Shaoqing Du , Kenji Yoshida , Ya Zhang , Ikutaro Hamada , Kazuhiko Hirakawa

The steps at the crystal surfaces could be transparent for the migrating adatoms. In the case of significant transparency the velocity of a given step in a given moment is affected by detachment of atoms from rather distant steps in rather…

Other Condensed Matter · Physics 2008-10-15 Bogdan Ranguelov , Stoyan Stoyanov

Here, we trap and control the position of droplets to study their dynamics using hydrodynamic forces alone without an external field. The hydrodynamic trap is adapted from a previously implemented Stokes trap by incorporating a…

Fluid Dynamics · Physics 2020-11-13 Shweta Narayan , Davis B. Moravec , Andrew J. Dallas , Cari S. Dutcher

A fundamental question in protein folding is whether the coil to globule collapse transition occurs during the initial stages of folding (burst-phase) or simultaneously with the protein folding transition. Single molecule fluorescence…

Biomolecules · Quantitative Biology 2016-03-01 Hiranmay Maity , Govardhan Reddy

Relaxor ferroelectrics, which can exhibit exceptional electromechanical coupling are some of the most important functional materials with applications ranging from ultrasound imaging to actuators and sensors in microelectromechanical…

We examine the applicability of the extended law of corresponding states (ELCS) to equilibrium and non equilibrium features of the state diagram of the globular protein lysozyme. We provide compelling evidence that the ELCS correctly…

Soft Condensed Matter · Physics 2012-12-10 Thomas Gibaud , Frederic Cardinaux , Johan Bergenholtz , Anna Stradner , Peter Schurtenberger

Simulating percolation and critical phenomena of labelled species inside films composed of single-component linear homogeneous macromolecules using molecular Monte Carlo method in 3 dimensions, we study dependence of these conducting…

Soft Condensed Matter · Physics 2019-09-05 Yuki Norizoe , Hiroshi Morita

Nonequilibrium steady states in an open system connecting two reservoirs of platelike colloidal particles are investigated by means of a recently proposed phenomenological dynamic density functional theory [M. Bier and R. van Roij, Phys.…

Soft Condensed Matter · Physics 2011-09-14 Markus Bier , Rene van Roij

Thermophilic enzymes can operate at higher temperatures but show reduced activities at room temperature. They are in general more stable during preparation and, accordingly, are considered to be more rigid in structure. Crystallization is…

Biomolecules · Quantitative Biology 2015-06-04 Eva Hammann , Andrea Zappe , Stefanie Keis , Stefan Ernst , Doreen Matthies , Thomas Meier , Gregory M. Cook , Michael Boersch

A key question in brain sciences is how to identify time-evolving functional connectivity, such as that obtained from recordings of neuronal activity over time. We wish to explain the observed phenomena in terms of latent states which, in…

Methodology · Statistics 2026-05-14 Yiwei Gong , Susanna B. Mierau , Sinead A. Williamson