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Most living systems rely on double-stranded DNA (dsDNA) to store their genetic information and perpetuate themselves. This biological information has been considered the main target of evolution. However, here we show that symmetries and…

Biomolecules · Quantitative Biology 2025-05-01 Piero Fariselli , Cristian Taccioli , Luca Pagani , Amos Maritan

Quantization has been an effective technology in ANN (approximate nearest neighbour) search due to its high accuracy and fast search speed. To meet the requirement of different applications, there is always a trade-off between retrieval…

Computer Vision and Pattern Recognition · Computer Science 2020-12-08 Jingkuan Song , Xiaosu Zhu , Lianli Gao , Xin-Shun Xu , Wu Liu , Heng Tao Shen

Motivated by average-case trace reconstruction and coding for portable DNA-based storage systems, we initiate the study of \emph{coded trace reconstruction}, the design and analysis of high-rate efficiently encodable codes that can be…

Information Theory · Computer Science 2019-09-11 Mahdi Cheraghchi , Ryan Gabrys , Olgica Milenkovic , João Ribeiro

A fundamental problem in coding theory is the design of an efficient coding scheme that achieves the capacity of the additive white Gaussian (AWGN) channel. The main objective of this short note is to point out that by concatenating a…

Information Theory · Computer Science 2016-08-24 Shashank Vatedka , Navin Kashyap

In this paper, we consider the problem of designing DNA sequences (codewords) for DNA storage systems and DNA computing that are unlikely to fold back onto themselves to form undesirable secondary structures. The paper addresses both the…

Discrete Mathematics · Computer Science 2016-11-17 Olgica Milenkovic , Navin Kashyap

Motivated by applications to DNA storage, we study reconstruction and list-reconstruction schemes for integer vectors that suffer from limited-magnitude errors. We characterize the asymptotic size of the intersection of error balls in…

Information Theory · Computer Science 2021-08-24 Hengjia Wei , Moshe Schwartz

Compression is beneficial because it helps detract resource usage. It reduces data storage space as well as transmission traffic and improves web pages loading. Run-length coding (RLC) is a lossless data compression algorithm. Data are…

Data Structures and Algorithms · Computer Science 2016-11-30 Kaveh Geyratmand Haghighi , Mirkamal Mirnia , Ahmad Habibizad Navin

This paper presents a memory-optimized metadata-based data structure for implementation of binary chromosome in Genetic Algorithm. In GA different types of genotypes are used depending on the problem domain. Among these, binary genotype is…

Neural and Evolutionary Computing · Computer Science 2021-03-09 Avijit Basak

Distributed systems store data objects redundantly to balance the data access load over multiple nodes. Load balancing performance depends mainly on 1) the level of storage redundancy and 2) the assignment of data objects to storage nodes.…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-12-19 Mehmet Aktas , Emina Soljanin

Code generation maps a program description to executable source code in a programming language. Existing approaches mainly rely on a recurrent neural network (RNN) as the decoder. However, we find that a program contains significantly more…

Machine Learning · Computer Science 2018-11-19 Zeyu Sun , Qihao Zhu , Lili Mou , Yingfei Xiong , Ge Li , Lu Zhang

This paper explores the design of convolutional codes for varying constraint lengths, focusing on their role in error correction in digital communication systems. Convolutional codes are essential in achieving reliable data transmission…

Information Theory · Computer Science 2024-10-03 Parag Dhounde , Avinash Bhute

Erasure coding techniques are used to increase the reliability of distributed storage systems while minimizing storage overhead. Also of interest is minimization of the bandwidth required to repair the system following a node failure. In a…

Information Theory · Computer Science 2009-10-06 K. V. Rashmi , Nihar B. Shah , P. Vijay Kumar , Kannan Ramchandran

In this paper, we study error exponents for a concatataned coding based class of DNA storage codes in which the number of reads performed can be variable. That is, the decoder can sequentially perform reads and choose whether to output the…

Information Theory · Computer Science 2025-04-25 Yan Hao Ling , Nir Weinberger , Jonathan Scarlett

The problem of reconstructing strings from their substring spectra has a long history and in its most simple incarnation asks for determining under which conditions the spectrum uniquely determines the string. We study the problem of coded…

Information Theory · Computer Science 2019-04-24 Ryan Gabrys , Olgica Milenkovic

DNA sequencing technology has advanced to a point where storage is becoming the central bottleneck in the acquisition and mining of more data. Large amounts of data are vital for genomics research, and generic compression tools, while…

Information Theory · Computer Science 2016-11-15 Bobbie Chern , Idoia Ochoa , Alexandros Manolakos , Albert No , Kartik Venkat , Tsachy Weissman

Regenerating codes allow distributed storage systems to recover from the loss of a storage node while transmitting the minimum possible amount of data across the network. We present a systematic computer search for optimal systematic…

Information Theory · Computer Science 2009-10-14 Daniel Cullina , Alexandros G. Dimakis , Tracey Ho

Data storage in DNA is developing as a possible solution for archival digital data. Recently, to further increase the potential capacity of DNA-based data storage systems, the combinatorial composite DNA synthesis method was suggested. This…

Information Theory · Computer Science 2024-05-28 Omer Sabary , Inbal Preuss , Ryan Gabrys , Zohar Yakhini , Leon Anavy , Eitan Yaakobi

Current research on DNA storage usually focuses on the improvement of storage density by developing effective encoding and decoding schemes while lacking the consideration on the uncertainty in ultra-long-term data storage and retention.…

Emerging Technologies · Computer Science 2022-08-10 Min Li , Jiashu Wu , Junbiao Dai , Qingshan Jiang , Qiang Qu , Xiaoluo Huang , Yang Wang

Transcription factor proteins bind specific DNA sequences to control the expression of genes. They contain DNA binding domains which belong to several super-families, each with a specific mechanism of DNA binding. The total number of…

Biomolecules · Quantitative Biology 2010-07-27 Shalev Itzkovitz , Tsvi Tlusty , Uri Alon

While many optimization problems work with a fixed number of decision variables and thus a fixed-length representation of possible solutions, genetic programming (GP) works on variable-length representations. A naturally occurring problem…

Neural and Evolutionary Computing · Computer Science 2018-06-07 Benjamin Doerr , Timo Kötzing , J. A. Gregor Lagodzinski , Johannes Lengler