Related papers: Fast Mitochondria Detection for Connectomics
Live cell culture is crucial in biomedical studies for analyzing cell properties and dynamics in vitro. This study focuses on segmenting unstained live cells imaged with bright-field microscopy. While many segmentation approaches exist for…
Alterations in retinal layer thickness, measurable using Optical Coherence Tomography (OCT), have been associated with neurodegenerative diseases such as Alzheimer's disease (AD). While previous studies have mainly focused on segmented…
Accurate detection of pathological conditions in human subjects can be achieved through off-line analysis of recorded biological signals such as electrocardiograms (ECGs). However, human diagnosis is time-consuming and expensive, as it…
White matter hyperintensities (WMH) are commonly found in the brains of healthy elderly individuals and have been associated with various neurological and geriatric disorders. In this paper, we present a study using deep fully convolutional…
Autism Spectrum Disorder(ASD) is a set of neurodevelopmental conditions that affect patients' social abilities. In recent years, many studies have employed deep learning to diagnose this brain dysfunction through functional MRI (fMRI).…
Mitochondria are complex organelles, and their proteomics analysis requires a combination of techniques. The emphasis in this chapter is made first on mitochondria preparation from cultured mammalian cells, then on the separation of the…
Cardiac arrhythmia, a condition characterized by irregular heartbeats, often serves as an early indication of various heart ailments. With the advent of deep learning, numerous innovative models have been introduced for diagnosing…
Dyslexia, affecting an estimated 10% to 20% of the global population, significantly impairs learning capabilities, highlighting the need for innovative and accessible diagnostic methods. This paper investigates the effectiveness of…
In ophthalmology, early fundus screening is an economic and effective way to prevent blindness caused by ophthalmic diseases. Clinically, due to the lack of medical resources, manual diagnosis is time-consuming and may delay the condition.…
Aiming at improving the efficiency and accuracy of community detection in complex networks, we proposed a new algorithm, which is based on the idea that communities could be detected from subnetworks by comparing the internal and external…
We introduce a novel framework that integrates Hodge decomposition with Filtered Average Short-Term (FAST) functional connectivity to analyze dynamic functional connectivity (DFC) in EEG signals. This method leverages graph-based topology…
The field of connectomics faces unprecedented "big data" challenges. To reconstruct neuronal connectivity, automated pixel-level segmentation is required for petabytes of streaming electron microscopy data. Existing algorithms provide…
Mitochondrial diseases are largely caused by dysfunction in mitochondrial proteins. However, annotations of human mitochondrial proteins are scattered across various public databases and individual studies. To facilitate research aimed at…
Autism spectrum disorder is one of the leading neurodevelopmental disorders in our world, present in over 1% of the population and rapidly increasing in prevalence, yet the condition lacks a robust, objective, and efficient diagnostic.…
Mining human-brain networks to discover patterns that can be used to discriminate between healthy individuals and patients affected by some neurological disorder, is a fundamental task in neuroscience. Learning simple and interpretable…
Depression is a serious mental health illness that significantly affects an individual's well-being and quality of life, making early detection crucial for adequate care and treatment. Detecting depression is often difficult, as it is based…
Functional Connectivity (FC) matrices measure the regional interactions in the brain and have been widely used in neurological brain disease classification. However, a FC matrix is neither a natural image which contains shape and texture…
Myocarditis is a significant cardiovascular disease (CVD) that poses a threat to the health of many individuals by causing damage to the myocardium. The occurrence of microbes and viruses, including the likes of HIV, plays a crucial role in…
Positron Emission Tomography / Computed Tomography (PET/CT) plays a critical role in medical imaging, combining functional and anatomical information to aid in accurate diagnosis. However, image quality degradation due to noise, compression…
Obsessive-compulsive disorder (OCD) is a common psychiatric disorder with a lifetime prevalence of 2-3 percent. Recently, brain activity in the resting state is gathering attention as a new means of exploring altered functional connectivity…