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In the study of shapes of human organs using computational anatomy, variations are found to arise from inter-subject anatomical differences, disease-specific effects, and measurement noise. This paper introduces a stochastic model for…

Computer Vision and Pattern Recognition · Computer Science 2016-12-19 Alexis Arnaudon , Darryl D. Holm , Akshay Pai , Stefan Sommer

Models of stochastic image deformation allow study of time-continuous stochastic effects transforming images by deforming the image domain. Applications include longitudinal medical image analysis with both population trends and random…

Computer Vision and Pattern Recognition · Computer Science 2022-12-08 Alexander Christgau , Alexis Arnaudon , Stefan Sommer

We introduce a stochastic model of diffeomorphisms, whose action on a variety of data types descends to stochastic evolution of shapes, images and landmarks. The stochasticity is introduced in the vector field which transports the data in…

Computer Vision and Pattern Recognition · Computer Science 2018-10-23 Alexis Arnaudon , Darryl D. Holm , Stefan Sommer

We present a method to predict image deformations based on patch-wise image appearance. Specifically, we design a patch-based deep encoder-decoder network which learns the pixel/voxel-wise mapping between image appearance and registration…

Computer Vision and Pattern Recognition · Computer Science 2016-07-11 Xiao Yang , Roland Kwitt , Marc Niethammer

We introduce a deep encoder-decoder architecture for image deformation prediction from multimodal images. Specifically, we design an image-patch-based deep network that jointly (i) learns an image similarity measure and (ii) the…

Computer Vision and Pattern Recognition · Computer Science 2017-04-03 Xiao Yang , Roland Kwitt , Martin Styner , Marc Niethammer

In this paper, we propose a new approach to deformable image registration that captures sliding motions. The large deformation diffeomorphic metric mapping (LDDMM) registration method faces challenges in representing sliding motion since it…

Optimization and Control · Mathematics 2023-03-15 Lili Bao , Jiahao Lu , Shihui Ying , Stefan Sommer

Matching of images and analysis of shape differences is traditionally pursued by energy minimization of paths of deformations acting to match the shape objects. In the Large Deformation Diffeomorphic Metric Mapping (LDDMM) framework,…

Computer Vision and Pattern Recognition · Computer Science 2018-10-23 Alexis Arnaudon , Darryl Holm , Stefan Sommer

Anatomy is undergoing a renaissance driven by availability of large digital data sets generated by light microscopy. A central computational task is to map individual data volumes to standardized templates. This is accomplished by…

Image and Video Processing · Electrical Eng. & Systems 2018-09-19 Daniel J. Tward , Partha Mitra , Michael I. Miller

In this paper, we propose a predictive regression model for longitudinal images with missing data based on large deformation diffeomorphic metric mapping (LDDMM) and deep neural networks. Instead of directly predicting image scans, our…

Computer Vision and Pattern Recognition · Computer Science 2018-08-24 Sharmin Pathan , Yi Hong

Deformable image registration plays an essential role in various medical image tasks. Existing deep learning-based deformable registration frameworks primarily utilize convolutional neural networks (CNNs) or Transformers to learn features…

Computer Vision and Pattern Recognition · Computer Science 2024-11-26 Jiong Wu , Kuang Gong

Image segmentation is a fundamental task in computer vision aimed at delineating object boundaries within images. Traditional approaches, such as edge detection and variational methods, have been widely explored, while recent advances in…

Computer Vision and Pattern Recognition · Computer Science 2025-06-12 Junchao Zhou

Advances in the development of largely automated microscopy methods such as MERFISH for imaging cellular structures in mouse brains are providing spatial detection of micron resolution gene expression. While there has been tremendous…

Numerical Analysis · Mathematics 2022-12-20 Michael I Miller , Alain Trouvé , Laurent Younes

Temporal volume images with 3D+t (4D) information are often used in medical imaging to statistically analyze temporal dynamics or capture disease progression. Although deep-learning-based generative models for natural images have been…

Image and Video Processing · Electrical Eng. & Systems 2022-06-28 Boah Kim , Jong Chul Ye

This paper discusses the mathematical framework for designing methods of large deformation matching (LDM) for image registration in computational anatomy. After reviewing the geometrical framework of LDM image registration methods, a…

Chaotic Dynamics · Physics 2015-04-09 M. Bruveris , F. Gay-Balmaz , D. D. Holm , T. S. Ratiu

This research presents a novel framework for the compression and decompression of medical images utilizing the Latent Diffusion Model (LDM). The LDM represents advancement over the denoising diffusion probabilistic model (DDPM) with a…

Image and Video Processing · Electrical Eng. & Systems 2023-10-10 InChan Hwang , MinJae Woo

In computational anatomy, the Large Deformation Diffeomorphic Metric Mapping (LDDMM) framework has become a central tool for modeling smooth, invertible transformations between shapes such as curves or landmarks. In this paper, we extend…

Differential Geometry · Mathematics 2025-11-19 Rayane Mouhli , Thomas Pierron

Dynamic mode decomposition (DMD) is a widely used data-driven algorithm for predicting the future states of dynamical systems. However, its standard formulation often struggles with poor long-term predictive accuracy. To address this…

Numerical Analysis · Mathematics 2026-04-21 Qiuqi Li , Chang Liu , Yifei Yang

In deformable registration, the geometric framework - large deformation diffeomorphic metric mapping or LDDMM, in short - has inspired numerous techniques for comparing, deforming, averaging and analyzing shapes or images. Grounded in…

Artificial Intelligence · Computer Science 2022-05-11 Boulbaba Ben Amor , Sylvain Arguillère , Ling Shao

We propose a new variational model for joint image reconstruction and motion estimation in spatiotemporal imaging, which is investigated along a general framework that we present with shape theory. This model consists of two components, one…

Numerical Analysis · Mathematics 2019-11-06 Chong Chen , Barbara Gris , Ozan Öktem

This paper describes how Large Deformation Diffeomorphic Metric Mapping (LDDMM) can be coupled with a Fast Multipole (FM) Boundary Element Method (BEM) to investigate the relationship between morphological changes in the head, torso, and…

Computational Geometry · Computer Science 2016-11-17 Reza Zolfaghari , Nicolas Epain , Craig T. Jin , Joan Glaunès , Anthony Tew
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