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Prompt optimization in compound AI systems is statistically indistinguishable from a coin flip: across 72 optimization runs on Claude Haiku 4.5 (6 methods $\times$ 4 tasks $\times$ 3 repeats), 49% score below zero-shot; on Amazon Nova Lite,…

Artificial Intelligence · Computer Science 2026-05-28 Xing Zhang , Guanghui Wang , Yanwei Cui , Wei Qiu , Ziyuan Li , Bing Zhu , Peiyang He

Traditional neuron models use analog values for information representation and computation, while all-or-nothing spikes are employed in the spiking ones. With a more brain-like processing paradigm, spiking neurons are more promising for…

Neural and Evolutionary Computing · Computer Science 2021-02-05 Qiang Yu , Shiming Song , Chenxiang Ma , Linqiang Pan , Kay Chen Tan

Implantable Brain-machine interfaces (BMIs) are promising for motor rehabilitation and mobility augmentation, and they demand accurate and energy-efficient algorithms. In this paper, we propose a novel spiking neural network (SNN) decoder…

Signal Processing · Electrical Eng. & Systems 2024-05-06 Jiawei Liao , Oscar Toomey , Xiaying Wang , Lars Widmer , Cynthia A. Chestek , Luca Benini , Taekwang Jang

Estimating the degree of synchrony or reliability between two or more spike trains is a frequent task in both experimental and computational neuroscience. In recent years, many different methods have been proposed that typically compare the…

Biological Physics · Physics 2012-12-11 Thomas Kreuz , Julie S. Haas , Alice Morelli , Henry D. I. Abarbanel , Antonio Politi

Advances in neuroscience have enabled researchers to measure the activities of large numbers of neurons simultaneously in behaving animals. We have access to the fluorescence of each of the neurons which provides a first-order approximation…

Neurons and Cognition · Quantitative Biology 2023-07-21 Abhisek Chakraborty

In recent years, new technologies in neuroscience have made it possible to measure the activities of large numbers of neurons simultaneously in behaving animals. For each neuron, a fluorescence trace is measured; this can be seen as a…

Applications · Statistics 2017-11-15 Sean Jewell , Daniela Witten

The increasing data rate has become a major issue confronting next-generation intracortical brain-machine interfaces (iBMIs). The scaling number of recording sites requires complex analog wiring and lead to huge digitization power…

Signal Processing · Electrical Eng. & Systems 2025-12-10 Ye Ke , Zhengnan Fu , Junyi Yang , Hongyang Shang , Arindam Basu

Spike sorting algorithms are used to separate extracellular recordings of neuronal populations into single-unit spike activities. The development of customized hardware implementing spike sorting algorithms is burgeoning. However, there is…

Machine Learning · Computer Science 2025-01-30 Tim Zhang , Corey Lammie , Mostafa Rahimi Azghadi , Amirali Amirsoleimani , Majid Ahmadi , Roman Genov

Brain-machine interfaces (BMIs) are promising for motor rehabilitation and mobility augmentation. High-accuracy and low-power algorithms are required to achieve implantable BMI systems. In this paper, we propose a novel spiking neural…

Signal Processing · Electrical Eng. & Systems 2022-10-13 Jiawei Liao , Lars Widmer , Xiaying Wang , Alfio Di Mauro , Samuel R. Nason-Tomaszewski , Cynthia A. Chestek , Luca Benini , Taekwang Jang

In the last decade, there have been major advances in clusterless decoding algorithms for neural data analysis. These algorithms use the theory of marked point processes to describe the joint activity of many neurons simultaneously, without…

Neurons and Cognition · Quantitative Biology 2025-12-09 Azar Ghahari , Uri T. Eden

Intracortical brain-machine interfaces require decoders that adapt continuously to neural signal instability while operating within strict memory budgets. We introduce a dual-timescale Hebbian accumulator learning rule for spiking neural…

Signal Processing · Electrical Eng. & Systems 2026-04-10 Sriram V. C. Nallani , Sahil Shah

Event-related desynchronization and synchronization (ERD/S) and movement-related cortical potential (MRCP) play an important role in brain-computer interfaces (BCI) for lower limb rehabilitation, particularly in standing and sitting.…

This work introduces a neuromorphic compression based neural sensing architecture with address-event representation inspired readout protocol for massively parallel, next-gen wireless iBMI. The architectural trade-offs and implications of…

Signal Processing · Electrical Eng. & Systems 2024-10-28 Vivek Mohan , Wee Peng Tay , Arindam Basu

This work presents an efficient decoding pipeline for neuromorphic implantable brain-machine interfaces (Neu-iBMI), leveraging sparse neural event data from an event-based neural sensing scheme. We introduce a tunable event filter…

Machine Learning · Computer Science 2025-05-12 Vivek Mohan , Biyan Zhou , Zhou Wang , Anil Bharath , Emmanuel Drakakis , Arindam Basu

Neurofeedback has proved to be useful in many instances. This technique is often used to address both medical issues and performance improvement. Despite the wide range of applications, no consensus has been reached about the optimal…

Neurons and Cognition · Quantitative Biology 2019-03-26 Inês Esteves , Wenya Nan , Cristiana Alves , Alexandre Calapez , Fernando Melício , Agostinho Rosa

Spiking Neural Networks (SNNs) are noted for their brain-like computation and energy efficiency, but their performance lags behind Artificial Neural Networks (ANNs) in tasks like image classification and object detection due to the limited…

Neural and Evolutionary Computing · Computer Science 2025-06-09 Binghao Ye , Wenjuan Li , Dong Wang , Man Yao , Bing Li , Weiming Hu , Dong Liang , Kun Shang

Generative AI has recently propelled the decoding of images from brain activity. How do these approaches scale with the amount and type of neural recordings? Here, we systematically compare image decoding from four types of non-invasive…

Image and Video Processing · Electrical Eng. & Systems 2025-01-29 Hubert Banville , Yohann Benchetrit , Stéphane d'Ascoli , Jérémy Rapin , Jean-Rémi King

Neuromorphic computing has recently gained momentum with the emergence of various neuromorphic processors. As the field advances, there is an increasing focus on developing training methods that can effectively leverage the unique…

Emerging Technologies · Computer Science 2025-04-15 Sanaz Mahmoodi Takaghaj , Jack Sampson

IBM TrueNorth chip uses digital spikes to perform neuromorphic computing and achieves ultrahigh execution parallelism and power efficiency. However, in TrueNorth chip, low quantization resolution of the synaptic weights and spikes…

Neural and Evolutionary Computing · Computer Science 2016-07-19 Wei Wen , Chunpeng Wu , Yandan Wang , Kent Nixon , Qing Wu , Mark Barnell , Hai Li , Yiran Chen

Manual annotation of spike-wave discharges (SWDs), the electrographic hallmark of absence seizures, is labor-intensive for long-term electroencephalography (EEG) monitoring studies. While machine learning approaches show promise for…