Related papers: Molecular contrast on phase-contrast microscope
In this paper we propose a workflow to detect and track mitotic cells in time-lapse microscopy image sequences. In order to avoid the requirement for cell lines expressing fluorescent markers and the associated phototoxicity, phase contrast…
Deep-ultraviolet (DUV) microscopy can provide label-free biochemical contrast by exploiting the intrinsic absorption of nucleic acids, proteins and lipids, offering chemically specific morphological information that complements structural…
Phase-sensitive coherent imaging exploits changes in the phases of backscattered light to observe tiny alterations of scattering structures or variations of the refractive index. But moving scatterers or a fluctuating refractive index…
This mini review focuses on conductance measurements through molecular junctions containing few tens of molecules, which are fabricated along two approaches: (i) conducting atomic force microscope contacting a self-assembled monolayers on…
The theoretical approach to describe the defocusing microscopy technique by U. Agero et al. [Phys. Rev. E {\bf 67}, 051904 (2003)] assumes that the size of the objective lens aperture is infinite. This treatment gives that the intensity at…
High harmonic generation in the interaction of femtosecond lasers with atoms and molecules opens the path to molecular orbital tomography and to probe the electronic dynamics with attosecond-{\AA}ngstr\"{o}m resolutions. Molecular orbital…
Molecular cavity optomechanics (COM), characterized by remarkably efficient optomechanical coupling enabled by a highly localized light field and ultra-small effective mode volume, holds significant promise for advancing applications in…
Optical coherence tomography (OCT) has seen widespread success as an in vivo clinical diagnostic 3D imaging modality, impacting areas including ophthalmology, cardiology, and gastroenterology. Despite its many advantages, such as high…
Fundamental optics such as lenses and prisms work by applying phase shifts to incoming light via the refractive index. In these macroscopic devices, many particles each contribute a miniscule phase shift, working together to impose a total…
Molecular collisions can be studied at very low relative kinetic energies, in the milliKelvin range, by merging codirectional beams with much higher translational energies, extending even to the kiloKelvin range, provided that the beam…
Quantum imaging is emerging as a transformative approach for biomedical applications, applying nonclassical properties of light, such as entanglement, squeezing, and quantum correlations, to overcome fundamental limits of conventional…
Jones-matrix optical coherence tomography (JM-OCT) is an extension of OCT that provides multiple types of optical contrasts of biological and clinical samples. JM-OCT measures the spatial distribution of the Jones matrix of the sample and…
Dynamic full-field optical coherence microscopy (d-FF-OCM) is a label-free imaging technique that captures intrinsic subcellular motions to generate functional contrast. This dynamic approach yields images with fluorescence-like contrast,…
As both computer vision models and biomedical datasets grow in size, there is an increasing need for efficient inference algorithms. We utilize cascade detectors to efficiently identify sparse objects in multiresolution images. Given an…
The scanning transmission electron microscope, a workhorse instrument in materials characterization, is being transformed into an atomic-scale material manipulation platform. With an eye on the trajectory of recent developments and the…
Nonlinear optical processes are used in biological microscopy to surpass the diffraction limit on resolution, image deeper into brain tissues, and identify biomolecules without exogenous labels. These techniques typically require high…
The direct imaging and characterization of Earth-like planets is among the most sought-after prizes in contemporary astrophysics, however current optical instrumentation delivers insufficient dynamic range to overcome the vast contrast…
Major biological discoveries have been made by interrogating living organisms with light. However, the limited penetration of unscattered photons within biological tissues severely limits the depth range covered by optical methods.…
A muon collider would be a powerful tool for exploring the energy-frontier with leptons, and would complement the studies now under way at the LHC. Such a device would offer several important benefits. Muons, like electrons, are point…
Medical image segmentation, or computing voxelwise semantic masks, is a fundamental yet challenging task to compute a voxel-level semantic mask. To increase the ability of encoder-decoder neural networks to perform this task across large…