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Quantifying uncertainty of predictions has been identified as one way to develop more trustworthy artificial intelligence (AI) models beyond conventional reporting of performance metrics. When considering their role in a clinical decision…

Background: Automated analysis of CT scans for abdominal organ measurement is crucial for improving diagnostic efficiency and reducing inter-observer variability. Manual segmentation and measurement of organs such as the kidneys, liver,…

Deep learning models (DLMs) can achieve state-of-the-art performance in histopathology image segmentation and classification, but have limited deployment potential in real-world clinical settings. Uncertainty estimates of DLMs can increase…

Image and Video Processing · Electrical Eng. & Systems 2024-12-31 Audrey Xie , Elhoucine Elfatimi , Sambuddha Ghosal , Pratik Shah

Lesion segmentation is a crucial step of the radiomic workflow. Manual segmentation requires long execution time and is prone to variability, impairing the realisation of radiomic studies and their robustness. In this study, a deep-learning…

Deep neural networks have shown great achievements in solving complex problems. However, there are fundamental problems that limit their real world applications. Lack of measurable criteria for estimating uncertainty in the network outputs…

Computer Vision and Pattern Recognition · Computer Science 2018-03-02 Alireza Norouzi , Ali Emami , S. M. Reza Soroushmehr , Nader Karimi , Shadrokh Samavi , Kayvan Najarian

Current state-of-the-art deep learning segmentation methods have not yet made a broad entrance into the clinical setting in spite of high demand for such automatic methods. One important reason is the lack of reliability caused by models…

Computer Vision and Pattern Recognition · Computer Science 2019-06-18 Jörg Sander , Bob D. de Vos , Jelmer M. Wolterink , Ivana Išgum

Purpose: To develop and evaluate a deep learning-based method that allows to perform myocardial infarct segmentation in a fully-automated way. Materials and Methods: For this retrospective study, a cascaded framework of two and…

Image and Video Processing · Electrical Eng. & Systems 2025-03-20 Matthias Schwab , Mathias Pamminger , Christian Kremser , Markus Haltmeier , Agnes Mayr

This study focuses on comparing deep learning methods for the segmentation and quantification of uncertainty in prostate segmentation from MRI images. The aim is to improve the workflow of prostate cancer detection and diagnosis. Seven…

Image and Video Processing · Electrical Eng. & Systems 2023-08-10 Pablo Cesar Quihui-Rubio , Daniel Flores-Araiza , Gilberto Ochoa-Ruiz , Miguel Gonzalez-Mendoza , Christian Mata

Measuring cross-sectional areas in ultrasound images is a standard tool to evaluate disease progress or treatment response. Often addressed today with supervised deep-learning segmentation approaches, existing solutions highly depend upon…

Image and Video Processing · Electrical Eng. & Systems 2023-08-21 Vanessa Gonzalez Duque , Leonhard Zirus , Yordanka Velikova , Nassir Navab , Diana Mateus

Carotid arteries vulnerable plaques are a crucial factor in the screening of atherosclerosis by ultrasound technique. However, the plaques are contaminated by various noises such as artifact, speckle noise, and manual segmentation may be…

Image and Video Processing · Electrical Eng. & Systems 2022-04-19 Yanchao Yuan , Cancheng Li , Lu Xu , Ke Zhang , Yang Hua , Jicong Zhang

Recent publications have shown that the segmentation accuracy of modern-day convolutional neural networks (CNN) applied on cardiac MRI can reach the inter-expert variability, a great achievement in this area of research. However, despite…

Image and Video Processing · Electrical Eng. & Systems 2020-06-17 Nathan Painchaud , Youssef Skandarani , Thierry Judge , Olivier Bernard , Alain Lalande , Pierre-Marc Jodoin

The Dice similarity coefficient (DSC) is both a widely used metric and loss function for biomedical image segmentation due to its robustness to class imbalance. However, it is well known that the DSC loss is poorly calibrated, resulting in…

Image and Video Processing · Electrical Eng. & Systems 2022-11-02 Michael Yeung , Leonardo Rundo , Yang Nan , Evis Sala , Carola-Bibiane Schönlieb , Guang Yang

Background and objective: Uncertainty quantification is a pivotal field that contributes to realizing reliable and robust systems. It becomes instrumental in fortifying safe decisions by providing complementary information, particularly…

Image and Video Processing · Electrical Eng. & Systems 2024-03-19 Jamil Fayyad , Shadi Alijani , Homayoun Najjaran

Image segmentation is a critical step in computational biomedical image analysis, typically evaluated using metrics like the Dice coefficient during training and validation. However, in clinical settings without manual annotations,…

Computer Vision and Pattern Recognition · Computer Science 2025-08-05 Sikha O K , Meritxell Riera-Marín , Adrian Galdran , Javier García Lopez , Julia Rodríguez-Comas , Gemma Piella , Miguel A. González Ballester

Late gadolinium enhanced (LGE) magnetic resonance (MR) imaging is widely established to assess the viability of myocardial tissue of patients after acute myocardial infarction (MI). We propose the Cascading Refinement CNN (CaRe-CNN), which…

Computer Vision and Pattern Recognition · Computer Science 2023-12-20 Franz Thaler , Matthias A. F. Gsell , Gernot Plank , Martin Urschler

Detecting and segmenting individual cells from microscopy images is critical to various life science applications. Traditional cell segmentation tools are often ill-suited for applications in brightfield microscopy due to poor contrast and…

Image and Video Processing · Electrical Eng. & Systems 2020-05-20 Rituparna Sarkar , Suvadip Mukherjee , Elisabeth Labruyère , Jean-Christophe Olivo-Marin

Cardiac magnetic resonance imaging improves on diagnosis of cardiovascular diseases by providing images at high spatiotemporal resolution. Manual evaluation of these time-series, however, is expensive and prone to biased and…

Computer Vision and Pattern Recognition · Computer Science 2018-04-06 Fabian Isensee , Paul Jaeger , Peter M. Full , Ivo Wolf , Sandy Engelhardt , Klaus H. Maier-Hein

In stable coronary artery disease (CAD), reduction in mortality and/or myocardial infarction with revascularization over medical therapy has not been reliably achieved. Coronary arteries are usually extracted to perform stenosis detection.…

Image and Video Processing · Electrical Eng. & Systems 2021-01-26 Chen Zhao , Haipeng Tang , Daniel McGonigle , Zhuo He , Chaoyang Zhang , Yu-Ping Wang , Hong-Wen Deng , Robert Bober , Weihua Zhou

Multi-sequence cardiac magnetic resonance (CMR) provides essential pathology information (scar and edema) to diagnose myocardial infarction. However, automatic pathology segmentation can be challenging due to the difficulty of effectively…

Image and Video Processing · Electrical Eng. & Systems 2022-01-17 Kai-Ni Wang , Xin Yang , Juzheng Miao , Lei Li , Jing Yao , Ping Zhou , Wufeng Xue , Guang-Quan Zhou , Xiahai Zhuang , Dong Ni

We introduce Bayesian QuickNAT for the automated quality control of whole-brain segmentation on MRI T1 scans. Next to the Bayesian fully convolutional neural network, we also present inherent measures of segmentation uncertainty that allow…

Computer Vision and Pattern Recognition · Computer Science 2018-11-27 Abhijit Guha Roy , Sailesh Conjeti , Nassir Navab , Christian Wachinger