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Age-related macular degeneration (AMD) is characterized by early micro-vascular alterations that can be captured non-invasively using optical coherence tomography angiography (OCTA), yet most deep learning (DL) models rely on global…
Carotid arteries vulnerable plaques are a crucial factor in the screening of atherosclerosis by ultrasound technique. However, the plaques are contaminated by various noises such as artifact, speckle noise, and manual segmentation may be…
Purpose: The motion of the common carotid artery tissue layers along the vessel axis during the cardiac cycle, observed in ultrasound imaging, is associated with the presence of established cardiovascular risk factors. However, the vast…
A common problem which is faced by the researchers when dealing with arterial carotid imaging data is the registration of the geometrical structures between different imaging modalities or different timesteps. The use of the "Patient…
Computed Tomography (CT) is a widely utilized imaging modality in clinical settings. Using densely acquired rotational X-ray arrays, CT can capture 3D spatial features. However, it is confronted with challenged such as significant time…
A common task in cryo-electron microscopy (cryo-EM) data processing is to compare three-dimensional density maps of macromolecules. In this paper, we propose an algorithm for aligning three-dimensional density maps that exploits common…
Three-dimensional late gadolinium enhanced (LGE) cardiac MR (CMR) of left atrial scar in patients with atrial fibrillation (AF) has recently emerged as a promising technique to stratify patients, to guide ablation therapy and to predict…
In this paper, we present an approach to enhance and improve the current normal map rendering technique. Our algorithm is based on semi-discrete Optimal Mass Transportation (OMT) theory and has a solid theoretical base. The key difference…
Mesh reconstruction of the cardiac anatomy from medical images is useful for shape and motion measurements and biophysics simulations to facilitate the assessment of cardiac function and health. However, 3D medical images are often acquired…
In this paper, we are concerned with the problem of creating flattening maps of simply-connected open surfaces in $\mathbb{R}^3$. Using a natural principle of density diffusion in physics, we propose an effective algorithm for computing…
Cardiac Magnetic Resonance (CMR) imaging is a critical tool for diagnosing and managing cardiovascular disease, yet its utility is often limited by the sparse acquisition of 2D short-axis slices, resulting in incomplete volumetric…
Medical image analysis faces significant challenges due to limited annotation data, particularly in three-dimensional carotid artery segmentation tasks, where existing datasets exhibit spatially discontinuous slice annotations with only a…
Population imaging studies rely upon good quality medical imagery before downstream image quantification. This study provides an automated approach to assess image quality from cardiovascular magnetic resonance (CMR) imaging at scale. We…
The segmentation and classification of carotid plaques in ultrasound images play important roles in the treatment of atherosclerosis and assessment for the risk of stroke. Although deep learning methods have been used for carotid plaque…
Computer-aided diagnosis for low-dose computed tomography (CT) based on deep learning has recently attracted attention as a first-line automatic testing tool because of its high accuracy and low radiation exposure. However, existing methods…
Delineating 3D blood vessels is essential for clinical diagnosis and treatment, however, is challenging due to complex structure variations and varied imaging conditions. Supervised deep learning has demonstrated its superior capacity in…
Cardiac magnetic resonance imaging is a valuable non-invasive tool for identifying cardiovascular diseases. For instance, Cine MRI is the benchmark modality for assessing the cardiac function and anatomy. On the other hand, multi-contrast…
Saliency maps have been widely used to interpret deep learning classifiers for Alzheimer's disease (AD). However, since AD is heterogeneous and has multiple subtypes, the pathological mechanism of AD remains not fully understood and may…
Optical coherence tomography (OCT) is a non-invasive 3D modality widely used in ophthalmology for imaging the retina. Achieving automated, anatomically coherent retinal layer segmentation on OCT is important for the detection and monitoring…
This paper proposes a novel method for computing bijective density-equalizing quasiconformal (DEQ) flattening maps for multiply-connected open surfaces. In conventional density-equalizing maps, shape deformations are solely driven by…