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Histopathological images contain abundant phenotypic information and pathological patterns, which are the gold standards for disease diagnosis and essential for the prediction of patient prognosis and treatment outcome. In recent years,…

Computer Vision and Pattern Recognition · Computer Science 2022-10-26 Linhao Qu , Siyu Liu , Xiaoyu Liu , Manning Wang , Zhijian Song

The rapid emergence of highly adaptable and reusable artificial intelligence (AI) models is set to revolutionize the medical field, particularly in the diagnosis and management of Parkinson's disease (PD). Currently, there are no effective…

Machine Learning · Computer Science 2025-02-18 Aite Zhao , Yongcan Liu , Xinglin Yu , Xinyue Xing

Diabetes Mellitus (DM) can lead to significant microvasculature disruptions that eventually causes diabetic retinopathy (DR), or complications in the eye due to diabetes. If left unchecked, this disease can increase over time and eventually…

Image and Video Processing · Electrical Eng. & Systems 2022-08-10 Meysam Tavakoli , Patrick Kelley

The inability to interpret the model prediction in semantically and visually meaningful ways is a well-known shortcoming of most existing computer-aided diagnosis methods. In this paper, we propose MDNet to establish a direct multimodal…

Computer Vision and Pattern Recognition · Computer Science 2017-07-11 Zizhao Zhang , Yuanpu Xie , Fuyong Xing , Mason McGough , Lin Yang

An optical microscopic examination of thinly cut stained tissue on glass slides prepared from a FFPE tissue blocks is the gold standard for tissue diagnostics. In addition, the diagnostic abilities and expertise of any pathologist is…

In recent years, the use of deep learning is becoming increasingly popular in computer vision. However, the effective training of deep architectures usually relies on huge sets of annotated data. This is critical in the medical field where…

Image and Video Processing · Electrical Eng. & Systems 2019-07-30 Paolo Andreini , Simone Bonechi , Monica Bianchini , Alessandro Mecocci , Franco Scarselli , Andrea Sodi

Deep Learning (DL) can predict biomarkers from cancer histopathology. Several clinically approved applications use this technology. Most approaches, however, predict categorical labels, whereas biomarkers are often continuous measurements.…

Diabetic retinopathy is a leading cause of blindness in diabetic patients and early detection plays a crucial role in preventing vision loss. Traditional diagnostic methods are often time-consuming and prone to errors. The emergence of deep…

Computer Vision and Pattern Recognition · Computer Science 2025-03-19 Saif Ur Rehman Khan , Muhammad Nabeel Asim , Sebastian Vollmer , Andreas Dengel

Medical image segmentation is an important task for computer aided diagnosis. Pixelwise manual annotations of large datasets require high expertise and is time consuming. Conventional data augmentations have limited benefit by not fully…

Image and Video Processing · Electrical Eng. & Systems 2020-04-28 Dwarikanath Mahapatra , Behzad Bozorgtabar , Jean-Philippe Thiran , Ling Shao

Automatic segmentation of retina vessels plays a pivotal role in clinical diagnosis of prevalent eye diseases, such as, Diabetic Retinopathy or Age-related Macular Degeneration. Due to the complex construction of blood vessels, with…

Image and Video Processing · Electrical Eng. & Systems 2023-02-21 Benjamin Hou

This paper presents a new method for medical diagnosis of neurodegenerative diseases, such as Parkinson's, by extracting and using latent information from trained Deep convolutional, or convolutional-recurrent Neural Networks (DNNs). In…

Machine Learning · Computer Science 2019-01-24 Ilianna Kollia , Andreas-Georgios Stafylopatis , Stefanos Kollias

Background: To determine the ability of a commercially available deep learning system, RetCAD v.1.3.1 (Thirona, Nijmegen, The Netherlands) for the automatic detection of referable diabetic retinopathy (DR) on a dataset of colour fundus…

Deep learning techniques are recently being used in fundus image analysis and diabetic retinopathy detection. Microaneurysms are an important indicator of diabetic retinopathy progression. We introduce a two-stage deep learning approach for…

Image and Video Processing · Electrical Eng. & Systems 2019-09-25 Mhd Hasan Sarhan , Shadi Albarqouni , Mehmet Yigitsoy , Nassir Navab , Abouzar Eslami

Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycemia due to insufficient insulin production or impaired insulin utilization. One of its most severe complications is diabetic retinopathy (DR), a…

Image and Video Processing · Electrical Eng. & Systems 2026-02-12 Ali El Bellaj , Aya Benradi , Salman El Youssoufi , Taha El Marzouki , Mohammed-Amine Cheddadi

Diabetic retinopathy (DR) is caused by long-standing diabetes and is among the fifth leading cause for visual impairments. The process of early diagnosis and treatments could be helpful in curing the disease, however, the detection…

Computer Vision and Pattern Recognition · Computer Science 2023-10-30 Chamuditha Jayanga Galappaththige , Gayal Kuruppu , Muhammad Haris Khan

Artificial Intelligence (AI)-powered pathology is a revolutionary step in the world of digital pathology and shows great promise to increase both diagnosis accuracy and efficiency. However, defocus and motion blur can obscure tissue or cell…

Image and Video Processing · Electrical Eng. & Systems 2020-11-25 Cheng Jiang , Jun Liao , Pei Dong , Zhaoxuan Ma , De Cai , Guoan Zheng , Yueping Liu , Hong Bu , Jianhua Yao

In this paper, we explore the possibility to apply machine learning to make diagnostic predictions using discomfort drawings. A discomfort drawing is an intuitive way for patients to express discomfort and pain related symptoms. These…

Machine Learning · Computer Science 2016-12-06 Cheng Zhang , Hedvig Kjellstrom , Bo C. Bertilson

Diabetic retinopathy refers to the pathology of the retina induced by diabetes and is one of the leading causes of preventable blindness in the world. Early detection of diabetic retinopathy is critical to avoid vision problem through…

Image and Video Processing · Electrical Eng. & Systems 2022-01-19 Malik A. Manan , Tariq M. Khan , Ahsan Saadat , Muhammad Arsalan , Syed S. Naqvi

The use of deep neural models for diagnosis prediction from clinical text has shown promising results. However, in clinical practice such models must not only be accurate, but provide doctors with interpretable and helpful results. We…

Diabetic eye disease is one of the fastest growing causes of preventable blindness. With the advent of anti-VEGF (vascular endothelial growth factor) therapies, it has become increasingly important to detect center-involved diabetic macular…