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Background: Missing data is a common challenge in mass spectrometry-based metabolomics, which can lead to biased and incomplete analyses. The integration of whole-genome sequencing (WGS) data with metabolomics data has emerged as a…

Variational autoencoders (VAEs), as well as other generative models, have been shown to be efficient and accurate for capturing the latent structure of vast amounts of complex high-dimensional data. However, existing VAEs can still not…

Machine Learning · Computer Science 2020-05-25 Alfredo Nazabal , Pablo M. Olmos , Zoubin Ghahramani , Isabel Valera

Missing data imputation (MDI) is a fundamental problem in many scientific disciplines. Popular methods for MDI use global statistics computed from the entire data set (e.g., the feature-wise medians), or build predictive models operating…

Machine Learning · Computer Science 2020-06-25 Indro Spinelli , Simone Scardapane , Aurelio Uncini

In order to predict and fill in the gaps in categorical datasets, this research looked into the use of machine learning algorithms. The emphasis was on ensemble models constructed using the Error Correction Output Codes framework, including…

Machine Learning · Computer Science 2024-09-13 Muhammad Ishaq , Sana Zahir , Laila Iftikhar , Mohammad Farhad Bulbul , Seungmin Rho , Mi Young Lee

Machine learning techniques have been developed to learn from complete data. When missing values exist in a dataset, the incomplete data should be preprocessed separately by removing data points with missing values or imputation. In this…

Machine Learning · Computer Science 2020-12-25 Hadi A. Khorshidi , Michael Kirley , Uwe Aickelin

Deep Learning (DL) methods have dramatically increased in popularity in recent years, with significant growth in their application to supervised learning problems in the biomedical sciences. However, the greater prevalence and complexity of…

Machine Learning · Statistics 2023-10-30 David K Lim , Naim U Rashid , Junier B Oliva , Joseph G Ibrahim

The recently proposed identifiable variational autoencoder (iVAE) framework provides a promising approach for learning latent independent components (ICs). iVAEs use auxiliary covariates to build an identifiable generation structure from…

Machine Learning · Statistics 2022-10-17 Young-geun Kim , Ying Liu , Xuexin Wei

The imputation of missing values in multivariate time series (MTS) data is critical in ensuring data quality and producing reliable data-driven predictive models. Apart from many statistical approaches, a few recent studies have proposed…

Machine Learning · Computer Science 2023-05-17 Maksims Kazijevs , Manar D. Samad

In the last couple of decades, there has been major advancements in the domain of missing data imputation. The techniques in the domain include amongst others: Expectation Maximization, Neural Networks with Evolutionary Algorithms or…

Neural and Evolutionary Computing · Computer Science 2015-12-07 Collins Leke , Tshilidzi Marwala , Satyakama Paul

Training deep generative models with maximum likelihood remains a challenge. The typical workaround is to use variational inference (VI) and maximize a lower bound to the log marginal likelihood of the data. Variational auto-encoders (VAEs)…

Machine Learning · Statistics 2019-08-13 Adji B. Dieng , John Paisley

Missing data is a ubiquitous challenge in data analysis, often leading to biased and inaccurate results. Traditional imputation methods usually assume that the missingness mechanism is missing-at-random (MAR), where the missingness is…

Methodology · Statistics 2026-03-30 Huiming Xie , Fei Xue , Xiao Wang

Deep neural network models trained on large labeled datasets are the state-of-the-art in a large variety of computer vision tasks. In many applications, however, labeled data is expensive to obtain or requires a time consuming manual…

Machine Learning · Computer Science 2017-12-01 Sergey Tulyakov , Andrew Fitzgibbon , Sebastian Nowozin

As the adoption of Artificial Intelligence (AI) models expands into critical real-world applications, ensuring the explainability of these models becomes paramount, particularly in sensitive fields such as medicine and finance. Linear…

Machine Learning · Computer Science 2024-10-10 Tuan L. Vo , Uyen Dang , Thu Nguyen

Advancements in data collection techniques and the heterogeneity of data resources can yield high percentages of missing observations on variables, such as block-wise missing data. Under missing-data scenarios, traditional methods such as…

Methodology · Statistics 2022-05-17 Wei Lan , Xuerong Chen , Tao Zou , Chih-Ling Tsai

Data analysis usually suffers from the Missing Not At Random (MNAR) problem, where the cause of the value missing is not fully observed. Compared to the naive Missing Completely At Random (MCAR) problem, it is more in line with the…

Machine Learning · Computer Science 2025-05-27 Jialei Chen , Yuanbo Xu , Pengyang Wang , Yongjian Yang

We investigate methods for parameter learning from incomplete data that is not missing at random. Likelihood-based methods then require the optimization of a profile likelihood that takes all possible missingness mechanisms into account.…

Methodology · Statistics 2012-07-02 Manfred Jaeger

Missing data are ubiquitous in empirical databases, yet statistical analyses typically require complete data matrices. Multiple imputation offers a principled solution for filling these gaps. This study evaluates the performance of several…

Computation · Statistics 2026-02-05 Enzo Porto Brasil

Missing data can pose a challenge for machine learning (ML) modeling. To address this, current approaches are categorized into feature imputation and label prediction and are primarily focused on handling missing data to enhance ML…

Machine Learning · Computer Science 2023-09-19 Laixin Xie , Yang Ouyang , Longfei Chen , Ziming Wu , Quan Li

The importance weighted autoencoder (IWAE) (Burda et al., 2016) is a popular variational-inference method which achieves a tighter evidence bound (and hence a lower bias) than standard variational autoencoders by optimising a multi-sample…

Machine Learning · Statistics 2019-09-20 Axel Finke , Alexandre H. Thiery

Due to complex experimental settings, missing values are common in biomedical data. To handle this issue, many methods have been proposed, from ignoring incomplete instances to various data imputation approaches. With the recent rise of…

Machine Learning · Computer Science 2020-05-14 Kristian Miok , Dong Nguyen-Doan , Marko Robnik-Šikonja , Daniela Zaharie