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Investigating the emergence of a particular cell type is a recurring theme in models of growing cellular populations. The evolution of resistance to therapy is a classic example. Common questions are: when does the cell type first occur,…

Populations and Evolution · Quantitative Biology 2019-06-19 Michael D. Nicholson , Tibor Antal

Understanding how cooperation evolves in structured populations remains a fundamental question across diverse disciplines. The problem of cooperation typically involves pairwise or group interactions among individuals. While prior studies…

Physics and Society · Physics 2025-06-26 Dini Wang , Peng Yi , Gang Yan , Feng Fu

The spreading dynamics of an epidemic and the collective behavioral pattern of the population over which it spreads are deeply intertwined and the latter can critically shape the outcome of the former. Motivated by this, we design a…

Populations and Evolution · Quantitative Biology 2021-08-25 Mengbin Ye , Lorenzo Zino , Alessandro Rizzo , Ming Cao

Ecology and evolution are inherently linked, and studying a mathematical model that considers both holds promise of insightful discoveries related to the dynamics of cooperation. In the present article, we use the prisoner's dilemma (PD)…

Populations and Evolution · Quantitative Biology 2021-08-10 Sayantan Nag Chowdhury , Srilena Kundu , Jeet Banerjee , Matjaž Perc , Dibakar Ghosh

Complex networks serve as abstract models for understanding real-world complex systems and provide frameworks for studying structured dynamical systems. This article addresses limitations in current studies on the exploration of individual…

Social and Information Networks · Computer Science 2025-10-14 Bin Pi , Liang-Jian Deng , Minyu Feng , Matjaž Perc , Jürgen Kurths

Biological systems reach organizational complexity that far exceeds the complexity of any known inanimate objects. Biological entities undoubtedly obey the laws of quantum physics and statistical mechanics. However, is modern physics…

Other Quantitative Biology · Quantitative Biology 2018-02-26 Mikhail I. Katsnelson , Yuri I. Wolf , Eugene V. Koonin

Empirical observations show that ecological communities can have a huge number of coexisting species, also with few or limited number of resources. These ecosystems are characterized by multiple type of interactions, in particular…

Populations and Evolution · Quantitative Biology 2018-05-18 Chengyi Tu , Samir Suweis , Jacopo Grillib , Marco Formentin , Amos Maritan

Empirical observations show that ecological communities can have a huge number of coexisting species, also with few or limited number of resources. These ecosystems are characterized by multiple type of interactions, in particular…

Populations and Evolution · Quantitative Biology 2018-05-21 Chengyi Tu , Samir Suweis , Jacopo Grilli , Marco Formentin , Amos Maritan

Tumor growth is often the result of the simultaneous development of two or more cancer cell populations. Their interaction between them characterizes the system evolution. To obtain information about these interactions we apply the recently…

Tissues and Organs · Quantitative Biology 2014-03-28 Lucas Barberis , Miaguel Ángel Pasquale , Carlos Alberto Condat

Without contributing, defectors take more benefit from social resources than cooperators which is the reflection of a specific character of individuals. However, natural physical mechanisms of our society promote cooperation. Thus, in the…

Populations and Evolution · Quantitative Biology 2021-09-16 Bijan Sarkar

Living species, ranging from bacteria to animals, exist in environmental conditions that exhibit spatial and temporal heterogeneity which requires them to adapt. Risk-spreading through spontaneous phenotypic variations is a known concept in…

Populations and Evolution · Quantitative Biology 2020-04-03 Aleksandra Ardaševa , Robert A. Gatenby , Alexander R. A. Anderson , Helen M. Byrne , Philip K. Maini , Tommaso Lorenzi

Interactions among individuals in natural populations often occur in a dynamically changing environment. Understanding the role of environmental variation in population dynamics has long been a central topic in theoretical ecology and…

Populations and Evolution · Quantitative Biology 2021-05-18 Feng Huang , Ming Cao , Long Wang

Cancer is a disease of cellular regulation, often initiated by genetic mutation within cells, and leading to a heterogeneous cell population within tissues. In the competition for nutrients and growth space within the tumors the phenotype…

Populations and Evolution · Quantitative Biology 2017-08-08 András Szabó , Roeland M. H. Merks

Evolutionary game theory offers a general framework to study how behaviors evolve by social learning in a population. This body of theory can accommodate a range of social dilemmas, or games, as well as real-world complexities such as…

Physics and Society · Physics 2025-10-08 Guocheng Wang , Qi Su , Long Wang , Joshua B. Plotkin

Whether or not cooperation is favored in evolutionary games on graphs depends on the population structure and spatial properties of the interaction network. Population structures can be expressed as configurations. Such configurations…

Populations and Evolution · Quantitative Biology 2019-03-21 Hendrik Richter

Recent work draws attention to community-community encounters ("coalescence") as likely an important factor shaping natural ecosystems. This work builds on MacArthur's classic model of competitive coexistence to investigate such…

Populations and Evolution · Quantitative Biology 2016-11-28 Mikhail Tikhonov

We study the interplay between evolutionary game and network structure and show how the dynamics of the game affect the growth pattern of the network and how the evolution of the network influence the cooperative behavior in the game.…

Physics and Society · Physics 2007-05-23 Jie Ren , Xiang Wu , Wen-Xu Wang , Guanrong Chen , Bing-Hong Wang

If two species exhibit different nonlinear responses to a single shared resource, and if each species modifies the resource dynamics such that this favors its competitor, they may stably coexist. This coexistence mechanism, known as…

Populations and Evolution · Quantitative Biology 2015-06-16 Florian Hartig , Tamara Münkemüller , Karin Johst , Ulf Dieckmann

Models of strategy evolution on static networks help us understand how population structure can promote the spread of traits like cooperation. One key mechanism is the formation of altruistic spatial clusters, where neighbors of a…

Physics and Society · Physics 2023-09-07 Qi Su , Alex McAvoy , Joshua B. Plotkin

Tumor cells invade individually or in groups, mediated by mechanical interactions between cells and their surrounding matrix. These multicellular dynamics are reminiscent of leader-follower coordination and epithelial-mesenchymal…

Cell Behavior · Quantitative Biology 2022-06-28 Alex M. Hruska , Haiqian Yang , Susan E. Leggett , Ming Guo , Ian Y. Wong