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We extend the family of problems that may be implemented on an adiabatic quantum optimizer (AQO). When a quadratic optimization problem has at least one set of discrete controls and the constraints are linear, we call this a quadratic…

Quantum Physics · Physics 2014-07-16 Rishabh Chandra , N. Tobias Jacobson , Jonathan E. Moussa , Steven H. Frankel , Sabre Kais

We introduce a framework for mapping NP-Hard problems to adiabatic quantum computing (AQC) architectures that are heavily restricted in both connectivity and dynamic range of couplings, for which minor-embedding -- the standard problem…

Quantum Physics · Physics 2019-11-13 Gary J. Mooney , Sam U. Y. Tonetto , Charles D. Hill , Lloyd C. L. Hollenberg

The quadratic unconstrained binary optimization (QUBO) problem arises in diverse optimization applications ranging from Ising spin problems to classical problems in graph theory and binary discrete optimization. The use of preprocessing to…

Artificial Intelligence · Computer Science 2017-05-29 Fred Glover , Mark Lewis , Gary Kochenberger

Graph embedding is a recurrent problem in quantum computing, for instance, quantum annealers need to solve a minor graph embedding in order to map a given Quadratic Unconstrained Binary Optimization (QUBO) problem onto their internal…

We show that the NP-hard quadratic unconstrained binary optimization (QUBO) problem on a graph $G$ can be solved using an adiabatic quantum computer that implements an Ising spin-1/2 Hamiltonian, by reduction through minor-embedding of $G$…

Quantum Physics · Physics 2009-07-16 Vicky Choi

Diagnosing the minimal set of faults capable of explaining a set of given observations, e.g., from sensor readouts, is a hard combinatorial optimization problem usually tackled with artificial intelligence techniques. We present the mapping…

Many artificial intelligence (AI) problems naturally map to NP-hard optimization problems. This has the interesting consequence that enabling human-level capability in machines often requires systems that can handle formally intractable…

Quantum Physics · Physics 2009-09-29 Hartmut Neven , Geordie Rose , William G. Macready

Variational quantum algorithms have been advocated as promising candidates to solve combinatorial optimization problems on near-term quantum computers. Their methodology involves transforming the optimization problem into a quadratic…

Quantum Physics · Physics 2023-08-01 Zoé Verchère , Sourour Elloumi , Andrea Simonetto

The peptide-protein docking problem is an important problem in structural biology that facilitates rational and efficient drug design. In this work, we explore modeling and solving this problem with the quantum-amenable quadratic…

The advent of quantum computing processors with possibility to scale beyond experimental capacities magnifies the importance of studying their applications. Combinatorial optimization problems can be one of the promising applications of…

Quantum Physics · Physics 2017-08-18 Ehsan Zahedinejad , Arman Zaribafiyan

A range of quantum algorithms, especially those leveraging variational parameterization and circuit-based optimization, are being studied as alternatives for solving classically intractable combinatorial optimization problems (COPs).…

Quantum Physics · Physics 2025-06-18 Monit Sharma , Hoong Chuin Lau

Adiabatic Quantum Computing (AQC) is an attractive paradigm for solving hard integer polynomial optimization problems. Available hardware restricts the Hamiltonians to be of a structure that allows only pairwise interactions. This requires…

Quantum Physics · Physics 2018-10-04 Raouf Dridi , Hedayat Alghassi , Sridhar Tayur

Quantum computing offers significant potential for solving NP-hard combinatorial (optimization) problems that are beyond the reach of classical computers. One way to tap into this potential is by reformulating combinatorial problems as a…

The Quadratic Unconstrained Binary Optimization problem (QUBO) has become a unifying model for representing a wide range of combinatorial optimization problems, and for linking a variety of disciplines that face these problems. A new class…

Artificial Intelligence · Computer Science 2017-05-30 Mark Lewis , Fred Glover

Ising machines are next-generation computers expected to efficiently sample near-optimal solutions of combinatorial optimization problems. Combinatorial optimization problems are modeled as quadratic unconstrained binary optimization (QUBO)…

Optimization and Control · Mathematics 2024-06-21 Kentaro Ohno , Nozomu Togawa

Quantum Annealing (QA) can be used to quickly obtain near-optimal solutions for Quadratic Unconstrained Binary Optimization (QUBO) problems. In QA hardware, each decision variable of a QUBO should be mapped to one or more adjacent qubits in…

Data Structures and Algorithms · Computer Science 2021-01-21 Thiago Serra , Teng Huang , Arvind Raghunathan , David Bergman

Adiabatic quantum programming defines the time-dependent mapping of a quantum algorithm into an underlying hardware or logical fabric. An essential step is embedding problem-specific information into the quantum logical fabric. We present…

Quantum Physics · Physics 2012-11-08 Christine Klymko , Blair D. Sullivan , Travis S. Humble

There is a growing interest in harnessing the potential of the Rydberg-atom system to address complex combinatorial optimization challenges. Here we present an experimental demonstration of how the quadratic unconstrained binary…

Quantum Physics · Physics 2024-07-03 Andrew Byun , Junwoo Jung , Kangheun Kim , Minhyuk Kim , Seokho Jeong , Heejeong Jeong , Jaewook Ahn

The D-Wave quantum annealers make it possible to obtain high quality solutions of NP-hard problems by mapping a problem in a QUBO (quadratic unconstrained binary optimization) or Ising form to the physical qubit connectivity structure on…

Quantum Physics · Physics 2022-12-29 Elijah Pelofske , Georg Hahn , Hristo Djidjev

In this paper, we develop a way to encode several NP-Complete problems in Abstract Argumentation to Quadratic Unconstrained Binary Optimization (QUBO) problems. In this form, a solution for a QUBO problem involves minimizing a quadratic…

Quantum Physics · Physics 2024-09-10 Marco Baioletti , Francesco Santini
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