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Automated blood vessel segmentation is vital for biomedical imaging, as vessel changes indicate many pathologies. Still, precise segmentation is difficult due to the complexity of vascular structures, anatomical variations across patients,…

Reliable cell segmentation and classification from biomedical images is a crucial step for both scientific research and clinical practice. A major challenge for more robust segmentation and classification methods is the large variations in…

Cell Behavior · Quantitative Biology 2017-10-31 Mo Zhang , Xiang Li , Mengjia Xu , Quanzheng Li

Blood vessels of the brain provide the human brain with the required nutrients and oxygen. As a vulnerable part of the cerebral blood supply, pathology of small vessels can cause serious problems such as Cerebral Small Vessel Diseases…

Segmentation of cerebral blood vessels from Magnetic Resonance Imaging (MRI) is an open problem that could be solved with deep learning (DL). However, annotated data for training is often scarce. Due to the absence of open-source tools, we…

Image and Video Processing · Electrical Eng. & Systems 2023-03-10 Georgia Kenyon , Stephan Lau , Michael A. Chappell , Mark Jenkinson

In this article, we look into some essential aspects of convolutional neural networks (CNNs) with the focus on medical image segmentation. First, we discuss the CNN architecture, thereby highlighting the spatial origin of the data,…

Computer Vision and Pattern Recognition · Computer Science 2022-11-18 Jeroen Bertels , David Robben , Robin Lemmens , Dirk Vandermeulen

The health and function of tissue rely on its vasculature network to provide reliable blood perfusion. Volumetric imaging approaches, such as multiphoton microscopy, are able to generate detailed 3D images of blood vessels that could…

Computer Vision and Pattern Recognition · Computer Science 2019-06-19 Mohammad Haft-Javaherian , Linjing Fang , Victorine Muse , Chris B. Schaffer , Nozomi Nishimura , Mert R. Sabuncu

Segmenting the retinal vasculature entails a trade-off between how much of the overall vascular structure we identify vs. how precisely we segment individual vessels. In particular, state-of-the-art methods tend to under-segment faint…

Computer Vision and Pattern Recognition · Computer Science 2019-03-28 Aashis Khanal , Rolando Estrada

BACKGROUND AND PURPOSE: Cerebral aneurysm is one of the most common cerebrovascular diseases, and SAH caused by its rupture has a very high mortality and disability rate. Existing automatic segmentation methods based on DLMs with TOF-MRA…

Image and Video Processing · Electrical Eng. & Systems 2021-10-27 Meng Chen , Chen Geng , Dongdong Wang , Jiajun Zhang , Ruoyu Di , Fengmei Li , Zhiyong Zhou , Sirong Piao , Yuxin Li , Yaikang Dai

Automatic blood vessel segmentation from retinal images plays an important role in the diagnosis of many systemic and eye diseases, including retinopathy of prematurity. Current state-of-the-art research in blood vessel segmentation from…

Image and Video Processing · Electrical Eng. & Systems 2023-06-21 Gorana Gojić , Veljko Petrović , Radovan Turović , Dinu Dragan , Ana Oros , Dušan Gajić , Nebojša Horvat

Segmenting a structural magnetic resonance imaging (MRI) scan is an important pre-processing step for analytic procedures and subsequent inferences about longitudinal tissue changes. Manual segmentation defines the current gold standard in…

Computer Vision and Pattern Recognition · Computer Science 2017-06-07 Alex Fedorov , Jeremy Johnson , Eswar Damaraju , Alexei Ozerin , Vince Calhoun , Sergey Plis

One of the major difficulties in medical image segmentation is the high variability of these images, which is caused by their origin (multi-centre), the acquisition protocols (multi-parametric), as well as the variability of human anatomy,…

Image and Video Processing · Electrical Eng. & Systems 2022-11-09 Jhon Jairo Saenz-Gamboa , Julio Domenech , Antonio Alonso-Manjarrés , Jon A. Gómez , Maria de la Iglesia-Vayá

Precise 3D segmentation of cerebral vasculature from T1-weighted contrast-enhanced (T1CE) MRI is crucial for safe neurosurgical planning. Manual delineation is time-consuming and prone to inter-observer variability, while current automated…

Computer Vision and Pattern Recognition · Computer Science 2025-11-25 Mohammad Jafari Vayeghan , Niloufar Delfan , Mehdi Tale Masouleh , Mansour Parvaresh Rizi , Behzad Moshiri

In recent years, deep convolutional neural networks (CNNs) have shown record-shattering performance in a variety of computer vision problems, such as visual object recognition, detection and segmentation. These methods have also been…

Computer Vision and Pattern Recognition · Computer Science 2019-07-30 Jose Bernal , Kaisar Kushibar , Daniel S. Asfaw , Sergi Valverde , Arnau Oliver , Robert Martí , Xavier Lladó

This paper analyzes the use of 3D Convolutional Neural Networks for brain tumor segmentation in MR images. We address the problem using three different architectures that combine fine and coarse features to obtain the final segmentation. We…

Machine Learning · Statistics 2017-05-24 Adrià Casamitjana , Santi Puch , Asier Aduriz , Verónica Vilaplana

Over recent years, increasingly complex approaches based on sophisticated convolutional neural network architectures have been slowly pushing performance on well-established benchmark datasets. In this paper, we take a step back to examine…

Image and Video Processing · Electrical Eng. & Systems 2021-12-22 Tariq M Khan , Antonio Robles-Kelly , Syed S. Naqvi

Brain tumor segmentation plays a pivotal role in medical image processing. In this work, we aim to segment brain MRI volumes. 3D convolution neural networks (CNN) such as 3D U-Net and V-Net employing 3D convolutions to capture the…

Computer Vision and Pattern Recognition · Computer Science 2019-09-24 Chen Chen , Xiaopeng Liu , Meng Ding , Junfeng Zheng , Jiangyun Li

Since the advent of U-Net, fully convolutional deep neural networks and its many variants have completely changed the modern landscape of deep learning based medical image segmentation. However, the over dependence of these methods on pixel…

Image and Video Processing · Electrical Eng. & Systems 2021-01-20 Simon Bohlender , Ilkay Oksuz , Anirban Mukhopadhyay

Motion artifacts caused by prolonged acquisition time are a significant challenge in Magnetic Resonance Imaging (MRI), hindering accurate tissue segmentation. These artifacts appear as blurred images that mimic tissue-like appearances,…

Image and Video Processing · Electrical Eng. & Systems 2024-12-06 Sunyoung Jung , Yoonseok Choi , Mohammed A. Al-masni , Minyoung Jung , Dong-Hyun Kim

Maps of brain microarchitecture are important for understanding neurological function and behavior, including alterations caused by chronic conditions such as neurodegenerative disease. Techniques such as knife-edge scanning microscopy…

Image and Video Processing · Electrical Eng. & Systems 2020-02-06 Leila Saadatifard , Aryan Mobiny , Pavel Govyadinov , Hien Nguyen , David Mayerich

Reconstructing the intricate local morphology of neurons and their long-range projecting axons can address many connectivity related questions in neuroscience. The main bottleneck in connectomics pipelines is correcting topological errors,…

Computer Vision and Pattern Recognition · Computer Science 2025-03-05 Anna Grim , Jayaram Chandrashekar , Uygar Sumbul