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As the frontline data for cancer diagnosis, microscopic pathology images are fundamental for providing patients with rapid and accurate treatment. However, despite their practical value, the deep learning community has largely overlooked…

Computer Vision and Pattern Recognition · Computer Science 2025-06-23 Sungrae Hong , Hyeongmin Park , Youngsin Ko , Sol Lee , Bryan Wong , Mun Yong Yi

Algorithmic bias in medical imaging can perpetuate health disparities, yet its causes remain poorly understood in segmentation tasks. While fairness has been extensively studied in classification, segmentation remains underexplored despite…

Image and Video Processing · Electrical Eng. & Systems 2025-11-04 Aditya Parikh , Sneha Das , Aasa Feragen

We propose a deep clustering architecture alongside image segmentation for medical image analysis. The main idea is based on unsupervised learning to cluster images on severity of the disease in the subject's sample, and this image is then…

Image and Video Processing · Electrical Eng. & Systems 2020-05-28 Sharmin Pathan , Anant Tripathi

Certain cancer types, notably pancreatic cancer, are difficult to detect at an early stage, motivating robust biomarker-based screening. Liquid biopsies enable non-invasive monitoring of circulating biomarkers, but typical machine learning…

Machine Learning · Computer Science 2025-11-21 Chongmin Lee , Jihie Kim

Clustering performs an essential role in many real world applications, such as market research, pattern recognition, data analysis, and image processing. However, due to the high dimensionality of the input feature values, the data being…

Machine Learning · Computer Science 2021-02-16 Si Lu , Ruisi Li

Quantitative medical image computing (radiomics) has been widely applied to build prediction models from medical images. However, overfitting is a significant issue in conventional radiomics, where a large number of radiomic features are…

Image and Video Processing · Electrical Eng. & Systems 2020-01-07 Jianan Chen , Laurent Milot , Helen M. C. Cheung , Anne L. Martel

Molecular data from tumor profiles is high dimensional. Tumor profiles can be characterized by tens of thousands of gene expression features. Due to the size of the gene expression feature set machine learning methods are exposed to noisy…

Machine Learning · Computer Science 2020-07-14 Martin Palazzo , Pierre Beauseroy , Patricio Yankilevich

Mitotic counting is a vital prognostic marker of tumor proliferation in breast cancer. Deep learning-based mitotic detection is on par with pathologists, but it requires large labeled data for training. We propose a deep classification…

Computer Vision and Pattern Recognition · Computer Science 2020-07-03 Pushpak Pati , Antonio Foncubierta-Rodriguez , Orcun Goksel , Maria Gabrani

The spectacular response observed in clinical trials of immunotherapy in patients with previously uncurable Melanoma, a highly aggressive form of skin cancer, calls for a better understanding of the cancer-immune interface. Computational…

Computer Vision and Pattern Recognition · Computer Science 2018-08-08 Konstantinos Zormpas-Petridis , Henrik Failmezger , Ioannis Roxanis , Matthew Blackledge , Yann Jamin , Yinyin Yuan

Accurate recurrence risk stratification is crucial for optimizing treatment plans for breast cancer patients. Current prognostic tools like Oncotype DX (ODX) offer valuable genomic insights for HR+/HER2- patients but are limited by cost and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-25 Ziyu Su , Yongxin Guo , Robert Wesolowski , Gary Tozbikian , Nathaniel S. O'Connell , M. Khalid Khan Niazi , Metin N. Gurcan

For brain tumour segmentation, deep learning models can achieve human expert-level performance given a large amount of data and pixel-level annotations. However, the expensive exercise of obtaining pixel-level annotations for large amounts…

Computer Vision and Pattern Recognition · Computer Science 2023-10-11 Xiao Liu , Antanas Kascenas , Hannah Watson , Sotirios A. Tsaftaris , Alison Q. O'Neil

Despite their black-box nature, deep learning models are extensively used in image-based drug discovery to extract feature vectors from single cells in microscopy images. To better understand how these networks perform representation…

Image and Video Processing · Electrical Eng. & Systems 2024-03-27 Vivek Gopalakrishnan , Jingzhe Ma , Zhiyong Xie

Test-time augmentation (TTA) is a well-known technique employed during the testing phase of computer vision tasks. It involves aggregating multiple augmented versions of input data. Combining predictions using a simple average formulation…

Computer Vision and Pattern Recognition · Computer Science 2024-08-28 Zeinab Sherkatghanad , Moloud Abdar , Mohammadreza Bakhtyari , Pawel Plawiak , Vladimir Makarenkov

This paper proposes Mutual Information Regularized Assignment (MIRA), a pseudo-labeling algorithm for unsupervised representation learning inspired by information maximization. We formulate online pseudo-labeling as an optimization problem…

Computer Vision and Pattern Recognition · Computer Science 2022-11-07 Dong Hoon Lee , Sungik Choi , Hyunwoo Kim , Sae-Young Chung

Data is one of the essential ingredients to power deep learning research. Small datasets, especially specific to medical institutes, bring challenges to deep learning training stage. This work aims to develop a practical deep multimodal…

Machine Learning · Computer Science 2019-02-26 Faik Aydin , Maggie Zhang , Michelle Ananda-Rajah , Gholamreza Haffari

Interpretability in machine learning models is important in high-stakes decisions, such as whether to order a biopsy based on a mammographic exam. Mammography poses important challenges that are not present in other computer vision tasks:…

Machine Learning · Computer Science 2021-03-24 Alina Jade Barnett , Fides Regina Schwartz , Chaofan Tao , Chaofan Chen , Yinhao Ren , Joseph Y. Lo , Cynthia Rudin

We present a way to use Topological Data Analysis (TDA) for machine learning tasks on grayscale images. We apply persistent homology to generate a wide range of topological features using a point cloud obtained from an image, its natural…

Machine Learning · Computer Science 2019-10-23 Adélie Garin , Guillaume Tauzin

In recent years Artificial Intelligence has emerged as a fundamental tool in medical applications. Despite this rapid development, deep neural networks remain black boxes that are difficult to explain, and this represents a major limitation…

Image and Video Processing · Electrical Eng. & Systems 2024-05-22 Tommaso Torda , Andrea Ciardiello , Simona Gargiulo , Greta Grillo , Simone Scardapane , Cecilia Voena , Stefano Giagu

Applying deep learning methods to mammography assessment has remained a challenging topic. Dense noise with sparse expressions, mega-pixel raw data resolution, lack of diverse examples have all been factors affecting performance. The lack…

Computer Vision and Pattern Recognition · Computer Science 2018-07-10 Ulzee An , Khader Shameer , Lakshmi Subramanian

This paper provides a critical review of the literature on deep learning applications in breast tumor diagnosis using ultrasound and mammography images. It also summarizes recent advances in computer-aided diagnosis (CAD) systems, which…

Image and Video Processing · Electrical Eng. & Systems 2020-10-05 Yuliana Jiménez-Gaona , María José Rodríguez-Álvarez , Vasudevan Lakshminarayanan