Related papers: Module concept and thermo-mechanical studies of th…
The TT-PET collaboration is developing a small animal TOF-PET scanner based on silicon detectors featuring 30 ps RMS time resolution and intended to be inserted in an existing MRI scanner. The TT-PET scanner makes use of a stack of layers…
The TT-PET collaboration is developing a PET scanner for small animals with 30 ps time-of-flight resolution and sub-millimetre 3D detection granularity. The sensitive element of the scanner is a monolithic silicon pixel detector based on…
Time-of-flight measurement is an important advancement in PET scanners to improve image reconstruction with a lower delivered radiation dose. This article describes the monolithic ASIC for the TT-PET project, a novel idea for a…
The TT-PET collaboration is developing a small animal TOF-PET scanner based on monolithic silicon pixel sensors in SiGe BiCMOS technology. The demonstrator chip, a small-scale version of the final detector ASIC, consists of a 3 x 10 pixel…
This paper describes the data acquisition and trigger system of the Thin Time-of-flight PET (TT-PET) scanner. The system is designed to read out in the order of 1000 pixel sensors used in the scanner and to provide a reference timing signal…
This work explores the combination of liquid xenon as a scintillating medium and silicon photomultipliers as a readout in Positron Emission Tomography (PET) for enhanced Time-Of-Flight resolution. We present the results of our first…
The potential of photon detectors to achieve precise timing information is of increasing importance in many domains, PET and CT scanners in medical imaging and particle physics detectors, amongst others. The goal to increase by an order of…
The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment…
The measurement of the time of flight of the two 511 keV gammas recorded in coincidence in a PET scanner provides an effective way of reducing the random background and therefore increases the scanner sensitivity, provided that the…
In the last years, high-resolution time tagging has emerged as the tool to tackle the problem of high-track density in the detectors of the next generation of experiments at particle colliders. Time resolutions below 50ps and event average…
Research conducted in the framework of the J-PET project aims to develop a cost-effective total-body positron emission tomography scanner. As a first step on the way to construct a full-scale J-PET tomograph from long strips of plastic…
This paper details preliminary photon measurements with the monolithic silicon detector ATLASPix, a pixel detector built and optimized for the CERN experiment ATLAS. The goal of this paper is to determine the promise of pixelated silicon in…
The foreseen CaLIPSO Positron Emission Tomography (PET) scanner is expected to yield simultaneously a fine image resolution, about 1 mm$^3$, and a high contrast. In this paper we present results of simulations for the full CaLIPSO PET…
The design of a detector system comprised of four silicon sensors bump-bonded to Timepix4 ASICs is described together with its data acquisition system, operational infrastructure, and dedicated software. The spatial and temporal performance…
The aim of this work is to show the potential capabilities of monolithic crystals coupled to large SiPM arrays, to be considered as detector blocks for PET scanners enabling Time Of Flight (TOF) capabilities. Monolithic blocks allow one to…
Small animal Positron Emission Tomography (PET) is dedicated to small animal imaging. Animals used in experiments, such as rats and monkeys, are often much smaller than human bodies, which requires higher position and energy precision of…
Liquid xenon offers several features, which make it suitable for applications in nuclear medicine, such as high scintillation yield and fast scintillation decay time. Moreover, being a continuous medium with a uniform response, liquid xenon…
The fast scintillation decay time and the high scintillation yield of liquid xenon makes it an appropriate material for nuclear medicine. Moreover, being a continuous medium with a uniform response, liquid xenon allows one to avoid most of…
In positron emission tomography acquisition (PET), sensitivity along a line of response can vary due to crystal geometrical arrangements in the scanner and/or detector inefficiencies, leading to severe artefacts in the reconstructed image.…
A PC based high speed silicon microstrip beam telescope consisting of several independent modules is presented. Every module contains an AC-coupled double sided silicon microstrip sensor and a complete set of analog and digital signal…