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Osteolytic metastases located in the vertebrae reduce strength and enhance the risk of vertebral fractures. This risk can be predicted by means of validated finite element models, but their reproducibility needs to be assessed. For that…

Tissues and Organs · Quantitative Biology 2025-03-24 W. Lokbani , V. Allard , T. Broussolle , CY. Barrey , C. B. Confavreux , K. Bruyere , JP. Roux , F. Bermond , H. Follet , D. Mitton

The incidence of vertebral fragility fracture is increased by the presence of preexisting pathologies such as metastatic disease. Computational tools could support the fracture prediction and consequently the decision of the best medical…

Computational Engineering, Finance, and Science · Computer Science 2024-02-16 Chiara Garavelli , Alessandra Aldieri , Marco Palanca , Enrico Dall'Ara , Marco Viceconti

The purpose of this study is to develop a deep learning based method that can automatically generate segmentations on cone-beam CT (CBCT) for head and neck online adaptive radiation therapy (ART), where expert-drawn contours in planning CT…

Medical Physics · Physics 2021-02-02 Xiao Liang , Howard Morgan , Dan Nguyen , Steve Jiang

We propose an ultrasound approach which provides, with one single examination and one single device, access to three bone biomarkers: anatomy, tissue quality and blood flow. It unlocks ultrasound imaging inside bone by accounting for…

Recent state-of-the-art performances of Vision Transformers (ViT) in computer vision tasks demonstrate that a general-purpose architecture, which implements long-range self-attention, could replace the local feature learning operations of…

We propose a method for estimating the bone mineral density (BMD) from a plain x-ray image. Dual-energy X-ray absorptiometry (DXA) and quantitative computed tomography (QCT) provide high accuracy in diagnosing osteoporosis; however, these…

Image and Video Processing · Electrical Eng. & Systems 2022-07-08 Yi Gu , Yoshito Otake , Keisuke Uemura , Mazen Soufi , Masaki Takao , Nobuhiko Sugano , Yoshinobu Sato

Currently, a large number of stored tissue samples are unavailable for spectroscopic study without the time consuming and destructive process of paraffin removal. Instead, a structurally sensitive technique, sum frequency generation, and a…

Medical Physics · Physics 2023-10-03 Bryan Semon , Michael Jaffe , Haifeng Wang , Lauren Priddy , Gombojav Ariunbold

Quantitative bone single-photon emission computed tomography (QBSPECT) has the potential to provide a better quantitative assessment of bone metastasis than planar bone scintigraphy due to its ability to better quantify activity in…

Computer Vision and Pattern Recognition · Computer Science 2021-05-31 Junyu Chen , Ye Li , Licia P. Luna , Hyun Woo Chung , Steven P. Rowe , Yong Du , Lilja B. Solnes , Eric C. Frey

Automatic medical image segmentation based on Computed Tomography (CT) has been widely applied for computer-aided surgery as a prerequisite. With the development of deep learning technologies, deep convolutional neural networks (DCNNs) have…

Image and Video Processing · Electrical Eng. & Systems 2021-04-09 Wenqiang Li , YM Tang , Ziyang Wang , KM Yu , Sandy To

Osteoporosis can be identified by looking at 2D x-ray images of the bone. The high degree of similarity between images of a healthy bone and a diseased one makes classification a challenge. A good bone texture characterization technique is…

Computer Vision and Pattern Recognition · Computer Science 2017-07-19 Rahul Paul , Saeed Alahamri , Sulav Malla , Ghulam Jilani Quadri

Deep-learning-based MR-to-CT synthesis can estimate the electron density of tissues, thereby facilitating PET attenuation correction in whole-body PET/MR imaging. However, whole-body MR-to-CT synthesis faces several challenges including the…

Image and Video Processing · Electrical Eng. & Systems 2024-11-27 Jiaxu Zheng , Zhenrong Shen , Lichi Zhang , Qun Chen

Vertebral detection and segmentation are critical steps for treatment planning in spine surgery and radiation therapy. Accurate identification and segmentation are complicated in imaging that does not include the full spine, in cases with…

Image and Video Processing · Electrical Eng. & Systems 2023-11-17 Geoff Klein , Michael Hardisty , Cari Whyne , Anne L. Martel

Imaging features of knee articular cartilage have been shown to be potential imaging biomarkers for knee osteoarthritis. Despite recent methodological advancements in image analysis techniques like image segmentation, registration, and…

Image and Video Processing · Electrical Eng. & Systems 2024-09-12 Yongcheng Yao , Weitian Chen

Osteoporosis is a skeletal disease typically diagnosed using dual-energy X-ray absorptiometry (DXA), which quantifies areal bone mineral density but overlooks bone microarchitecture and surrounding soft tissues. High-resolution peripheral…

Computer Vision and Pattern Recognition · Computer Science 2026-03-12 Mohseu Rashid Subah , Mohammed Abdul Gani Zilani , Thomas L. Nickolas , Matthew R. Allen , Stuart J. Warden , Rachel K. Surowiec

The automated detection of cortical lesions (CLs) in patients with multiple sclerosis (MS) is a challenging task that, despite its clinical relevance, has received very little attention. Accurate detection of the small and scarce lesions…

Image and Video Processing · Electrical Eng. & Systems 2020-08-18 Francesco La Rosa , Erin S Beck , Ahmed Abdulkadir , Jean-Philippe Thiran , Daniel S Reich , Pascal Sati , Meritxell Bach Cuadra

Confirming Alzheimer's disease (AD) typically relies on positron emission tomography (PET), which remains costly and invasive, motivating the use of structural MRI-based prescreening. Deep learning on non-Euclidean manifolds, particularly…

Computer Vision and Pattern Recognition · Computer Science 2026-05-27 Geonwoo Baek , Ikbeom Jang

Optical coherence tomography (OCT) can provide high-resolution cross-sectional images for analyzing superficial plaques in coronary arteries. Commonly, plaque characterization using intra-coronary OCT images is performed manually by expert…

Computer Vision and Pattern Recognition · Computer Science 2018-07-11 Shenghua He , Jie Zheng , Akiko Maehara , Gary Mintz , Dalin Tang , Mark Anastasio , Hua Li

Automatic vertebrae identification and localization from arbitrary CT images is challenging. Vertebrae usually share similar morphological appearance. Because of pathology and the arbitrary field-of-view of CT scans, one can hardly rely on…

Computer Vision and Pattern Recognition · Computer Science 2018-12-11 Haofu Liao , Addisu Mesfin , Jiebo Luo

Osteoporosis is a common condition that increases fracture risk, especially in older adults. Early diagnosis is vital for preventing fractures, reducing treatment costs, and preserving mobility. However, healthcare providers face challenges…

Computer Vision and Pattern Recognition · Computer Science 2025-10-21 Mehdi Hosseini Chagahi , Saeed Mohammadi Dashtaki , Niloufar Delfan , Nadia Mohammadi , Farshid Rostami Pouria , Behzad Moshiri , Md. Jalil Piran , Oliver Faust

We propose an auto-encoding network architecture for point clouds (PC) capable of extracting shape signatures without supervision. Building on this, we (i) design a loss function capable of modelling data variance on PCs which are…

Image and Video Processing · Electrical Eng. & Systems 2019-08-06 Anjany Sekuboyina , Markus Rempfler , Alexander Valentinitsch , Maximilian Loeffler , Jan S. Kirschke , Bjoern H. Menze