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Animals possess a remarkable ability to navigate challenging terrains, achieved through the interplay of various pathways between the brain, central pattern generators (CPGs) in the spinal cord, and musculoskeletal system. Traditional…

Robotics · Computer Science 2024-04-30 Ge Sun , Milad Shafiee , Peizhuo Li , Guillaume Bellegarda , Auke Ijspeert , Guillaume Sartoretti

Biological studies reveal that neural circuits located at the spinal cord called central pattern generator (CPG) oscillates and generates rhythmic signals, which are the underlying mechanism responsible for rhythmic locomotion behaviors of…

Robotics · Computer Science 2023-05-15 Chuanyu Yang , Can Pu , Tianqi Wei , Cong Wang , Zhibin Li

Animals must integrate sensory cues with their current behavioral context to generate a suitable response. How this integration occurs is poorly understood. Previously we developed high throughput methods to probe neural activity in…

Neurons and Cognition · Quantitative Biology 2023-09-25 Sandeep Kumar , Anuj K Sharma , Andrew Tran , Andrew M Leifer

C. elegans locomotion is composed of switches between forward and reversal states punctuated by turns. This locomotory capability is necessary for the nematode to move towards attractive stimuli, escape noxious chemicals, and explore its…

Neurons and Cognition · Quantitative Biology 2025-01-03 Megan Morrison , Lai-Sang Young

Cyborg in the brain-machine interface field has attracted more attention in recent years. To control a creature via a machine called cyborg method, three stages are considerable: stimulation of neurons, neural response, and the behavioral…

Biological Physics · Physics 2019-05-01 Mohammad Jamali , Yousef Jamali , Mehdi Golshani

Quadruped animal locomotion emerges from the interactions between the spinal central pattern generator (CPG), sensory feedback, and supraspinal drive signals from the brain. Computational models of CPGs have been widely used for…

Robotics · Computer Science 2023-02-28 Milad Shafiee , Guillaume Bellegarda , Auke Ijspeert

Neuromorphic computing systems, where information is transmitted through action potentials in a bio-plausible fashion, is gaining increasing interest due to its promise of low-power event-driven computing. Application of neuromorphic…

Neural and Evolutionary Computing · Computer Science 2025-09-03 Zhuangyu Han , Abhronil Sengupta

We investigate how locomotory behavior is generated in the brain focusing on the paradigmatic connectome of nematode Caenorhabditis elegans (C. elegans) and on neuronal activity patterns that control forward locomotion. We map the neuronal…

Adaptation and Self-Organizing Systems · Physics 2020-06-17 Thomas Maertens , Eckehard Schöll , Jorge Ruiz , Philipp Hövel

To establish the relationship between locomotory behavior and dynamics of neural circuits in the nematode C. elegans we combined molecular and theoretical approaches. In particular, we quantitatively analyzed the motion of C. elegans with…

Neurons and Cognition · Quantitative Biology 2008-06-10 Jan Karbowski , Gary Schindelman , Chris J. Cronin , Adeline Seah , Paul W. Sternberg

In this paper, we present a new locomotion control method for soft robot snakes. Inspired by biological snakes, our control architecture is composed of two key modules: A deep reinforcement learning (RL) module for achieving adaptive…

Robotics · Computer Science 2020-03-04 Xuan Liu , Renato Gasoto , Cagdas Onal , Jie Fu

Accurate and robust recording and decoding from the central nervous system (CNS) is essential for advances in human-machine interfacing. However, technologies used to directly measure CNS activity are limited by their resolution,…

Neurons and Cognition · Quantitative Biology 2025-09-19 Jaime Ibáñez , Blanka Zicher , Etienne Burdet , Stuart N. Baker , Carsten Mehring , Dario Farina

C. elegans is the only animal for which a detailed neural connectivity diagram has been constructed. However, synaptic polarities in this diagram, and thus, circuit functions are largely unknown. Here, we deciphered the likely polarities of…

Neurons and Cognition · Quantitative Biology 2014-03-21 Franciszek Rakowski , Jagan Srinivasan , Paul W. Sternberg , Jan Karbowski

The dynamic flow of cerebrospinal fluid (CSF) in brain ventricles exhibits flow features on several scales, both spatially and temporally. Most analysis of this complex flow and the accompanying transport has used instantaneous (Eulerian)…

Fluid Dynamics · Physics 2026-03-20 Halvor Herlyng , Shawn C. Shadden

This paper aims to solve the contact-aware locomotion problem of a soft snake robot by developing bio-inspired contact-aware locomotion controllers. To provide effective contact information for the controllers, we develop a scale-covered…

Robotics · Computer Science 2023-11-16 Xuan Liu , Cagdas D. Onal , Jie Fu

Small groups of interneurons, abbreviated by CPG for central pattern generators, are arranged into neural networks to generate a variety of core bursting rhythms with specific phase-locked states, on distinct time scales, that govern vital…

Chaotic Dynamics · Physics 2015-06-17 Sajiya Jalil , Dane Allen , Joe Youker , Andrey Shilnikov

All vertebrates are capable of performing various types of physical activity. Locomotor patterns are created by the cyclical coordinated work of the skeletal muscles. The organization of such a system in living organisms is responsible for…

Neurons and Cognition · Quantitative Biology 2021-12-15 A. I. Zharinov , Y. A. Tsybina , S. Y. Gordleeva

Targeted electrical stimulation of the brain perturbs neural networks and modulates their rhythmic activity both at the site of stimulation and at remote brain regions. Understanding, or even predicting, this neuromodulatory effect is…

Neurons and Cognition · Quantitative Biology 2021-06-29 Christoforos Papasavvas , Peter Neal Taylor , Yujiang Wang

Synchronization plays a key role in information processing in neuronal networks. Response of specific groups of neurons are triggered by external stimuli, such as visual, tactile or olfactory inputs. Neurons, however, can be divided into…

Adaptation and Self-Organizing Systems · Physics 2020-03-02 Carolina A. Moreira , Marcus A. M. de Aguiar

Central Pattern Generators (CPGs) models have been long used to investigate both the neural mechanisms that underlie animal locomotion as well as a tool for robotic research. In this work we propose a spiking CPG neural network and its…

Mammalian functional architecture flexibly adapts, transitioning from integration where information is distributed across the cortex, to segregation where information is focal in densely connected communities of brain regions. This…

Neurons and Cognition · Quantitative Biology 2025-04-03 Kimberly Nestor
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