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Mid-infrared light scatters much less than shorter wavelengths, allowing greatly enhanced penetration depths for optical imaging techniques such as optical coherence tomography (OCT). However, both detection and broadband sources in the…

Current optoacoustic microscopy configurations often have narrow focal ranges that limit their use for fast volumetric imaging applications. Here, the focal range of optoacoustic microscopes is extended by matching the elongated optical…

Optics · Physics 2021-04-15 Zakiullah Ali , Christian Zakian , Vasilis Ntziachristos

Strong speckle noise is inherent to optical coherence tomography (OCT) imaging and represents a significant obstacle for accurate quantitative analysis of retinal structures which is key for advances in clinical diagnosis and monitoring of…

Image and Video Processing · Electrical Eng. & Systems 2023-12-11 Shijie Li , Palaiologos Alexopoulos , Anse Vellappally , Ronald Zambrano , Wollstein Gadi , Guido Gerig

Current and future high contrast imaging instruments aim to detect exoplanets at closer orbital separations, lower masses, and/or older ages than their predecessors. However, continually evolving speckles in the coronagraphic science image…

Instrumentation and Methods for Astrophysics · Physics 2022-06-22 Benjamin L. Gerard , Daren Dillon , Sylvain Cetre , Rebecca Jensen-Clem

We present a novel acousto-optic lens (AOL) design for neutral atom quantum computing. This approach enhances atom rearrangement in optical tweezer arrays and addresses the speed limitations imposed by the cylindrical lensing effect of…

The next generation of large ground-based optical and infrared telescopes will provide new challenges for designers of astronomical instrumentation. The varied science cases for these extremely large telescopes (ELTs) require a large range…

Astrophysics · Physics 2009-11-13 Colin Cunningham , Chris Evans , Guy Monnet , Miska Le Louarn

Adaptive optics (AO) systems and image reconstruction algorithms are indispensable tools when it comes to high-precision astrometry. In this paper, we analyze the potential of combining both techniques, i.e. by applying image reconstruction…

Instrumentation and Methods for Astrophysics · Physics 2019-03-13 Felix Bosco , Jörg-Uwe Pott , Rainer Schödel

Current spectroscopic optical coherence tomography (OCT) methods rely on a posteriori numerical calculation. We present an alternative for accessing optically the spectroscopic information in OCT, i.e. without any post-processing, by using…

Quantum-optical coherence tomography (QOCT) is an optical sectioning modality based on the quantum interference of photon pairs, obtained from a spontaneous parametric downconversion (SPDC) source. The promise of QOCT derives from two…

Optical diffraction tomography (ODT) has emerged as a powerful label-free three-dimensional (3D) bioimaging techniques for observing living cells and thin tissue layers. We report a new reflection-mode ODT (rODT) method for imaging thick…

Optical Coherence Tomography (OCT) is a non-invasive depth resolved optical imaging modality, that enables high resolution, cross-sectional imaging in biological tissues and materials at clinically relevant depths. Though OCT offers high…

Medical Physics · Physics 2020-05-29 Cerine Lal , Sergey Alexandrov , Sweta Rani , Yi Zhou , Thomas Ritter , Martin Leahy

A new formulation of lateral imaging process of point-scanning optical coherence tomography (OCT) and a new differential contrast method designed by using this formulation are presented. The formulation is based on a mathematical sample…

Optical coherence tomography angiography (OCTA) is a novel and clinically promising imaging modality to image retinal and sub-retinal vasculature. Based on repeated optical coherence tomography (OCT) scans, intensity changes are observed…

Image and Video Processing · Electrical Eng. & Systems 2020-10-30 Lennart Husvogt , Stefan B. Ploner , Siyu Chen , Daniel Stromer , Julia Schottenhamml , A. Yasin Alibhai , Eric Moult , Nadia K. Waheed , James G. Fujimoto , Andreas Maier

I propose a superoscillation measurement method for subdiffraction incoherent optical sources, with potential applications in astronomy, remote sensing, fluorescence microscopy, and spectroscopy. The proposal, based on coherent optical…

Quantum Physics · Physics 2022-10-10 Mankei Tsang

In a medium where the dielectric permittivity is perturbed in the presence of an acoustic wave, optical scattering generates frequency-shifted light. In this paper we consider the inverse problem of recovering the optical properties of this…

Analysis of PDEs · Mathematics 2019-10-14 Francis J. Chung , Jeremy G. Hoskins , John C. Schotland

In optical coherence tomography (OCT), axial resolution and signal-to-noise ratio (SNR) are typically viewed as uncoupled parameters. We show that this is only true for mirror-like surfaces, and that in diffuse scattering samples such as…

Optics · Physics 2022-04-06 Danielle J. Harper , Benjamin J. Vakoc

Anterior segment optical coherence tomography (AS-OCT) is a non-invasive imaging technique that is highly valuable for ophthalmic diagnosis. However, speckles in AS-OCT images can often degrade the image quality and affect clinical…

Graphics · Computer Science 2023-07-03 Li Sanqian , Higashita Risa , Fu Huazhu , Li Heng , Niu Jingxuan , Liu Jiang

High anisotropy in volumetric medical images can lead to the inconsistent quantification of anatomical and pathological structures. Particularly in optical coherence tomography (OCT), slice spacing can substantially vary across and within…

Image and Video Processing · Electrical Eng. & Systems 2024-10-15 Coen de Vente , Mohammad Mohaiminul Islam , Philippe Valmaggia , Carel Hoyng , Adnan Tufail , Clara I. Sánchez

Quantum Optical Coherence Tomography (Q-OCT) uses quantum properties of light to provide several advantages over its classical counterpart, OCT: it achieves a twice better axial resolution with the same spectral bandwidth and it is immune…

Optics · Physics 2021-01-14 Sylwia M. Kolenderska , Piotr Kolenderski

We demonstrate in vivo endoscopic optical coherence tomography (OCT) imaging in the forward direction using a flexible fiber bundle. In comparison to current conventional forward looking probe schemes, our approach simplifies the endoscope…

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