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Density functional theory (DFT) has become a standard tool for the study of point defects in materials. However, finding the most stable defective structures remains a very challenging task as it involves the solution of a multimodal…

Materials Science · Physics 2020-11-16 Marco Arrigoni , Georg K. H. Madsen

Dynamic Fault Trees (DFTs) is a widely used failure modeling technique that allows capturing the dynamic failure characteristics of systems in a very effective manner. Simulation and model checking have been traditionally used for the…

Logic in Computer Science · Computer Science 2018-08-01 Yassmeen Elderhalli , Waqar Ahmad , Osman Hasan , Sofiene Tahar

The time-consuming nature of training and deploying complicated Machine and Deep Learning (DL) models for a variety of applications continues to pose significant challenges in the field of Machine Learning (ML). These challenges are…

Accurate molecular property prediction is central to drug discovery, catalysis, and process design, yet real-world applications are often limited by small datasets. Molecular foundation models provide a promising direction by learning…

Machine Learning · Computer Science 2026-04-21 Karim K. Ben Hicham , Jan G. Rittig , Martin Grohe , Alexander Mitsos

The concepts of sparsity, and regularised estimation, have proven useful in many high-dimensional statistical applications. Dynamic factor models (DFMs) provide a parsimonious approach to modelling high-dimensional time series, however, it…

Methodology · Statistics 2023-03-22 Luke Mosley , Tak-Shing T. Chan , Alex Gibberd

The discovery of drug-target interactions (DTIs) is a very promising area of research with great potential. The accurate identification of reliable interactions among drugs and proteins via computational methods, which typically leverage…

Quantitative Methods · Quantitative Biology 2022-12-06 Bin Liu , Dimitrios Papadopoulos , Fragkiskos D. Malliaros , Grigorios Tsoumakas , Apostolos N. Papadopoulos

Medium-entropy alloys (MEAs) such as CoCrFeNi and CoCrNi are promising structural materials owing to their outstanding mechanical and thermal properties, which arise from complex chemical disorder and atomic-scale interactions. Although…

Materials Science · Physics 2025-09-16 Mashroor S. Nitol , Artur Tamm , Subah Mubassira , Shuozhi Xu , Saryu J. Fensin

Machine learning force fields (MLFFs) are gaining attention as an alternative to classical force fields (FFs) by using deep learning models trained on density functional theory (DFT) data to improve interatomic potential accuracy. In this…

Chemical Physics · Physics 2025-03-25 Anseong Park , Jaeyune Ryu , Won Bo Lee

Factorization Machines (FMs) are effective in incorporating side information to overcome the cold-start and data sparsity problems in recommender systems. Traditional FMs adopt the inner product to model the second-order interactions…

Information Retrieval · Computer Science 2020-10-27 Yangyang Guo , Zhiyong Cheng , Jiazheng Jing , Yanpeng Lin , Liqiang Nie , Meng Wang

Simulating the dynamics of ions near polarizable nanoparticles (NPs) using coarse-grained models is extremely challenging due to the need to solve the Poisson equation at every simulation timestep. Recently, a molecular dynamics (MD) method…

Computational Physics · Physics 2019-11-01 JCS Kadupitiya , Geoffrey C. Fox , Vikram Jadhao

We present a comprehensive methodology to enable addition of van der Waals (vdW) corrections to machine learning (ML) atomistic force fields. Using a Gaussian approximation potential (GAP) [Bart\'ok et al., Phys. Rev. Lett. 104, 136403…

For the theoretical understanding of the reactivity of complex chemical systems accurate relative energies between intermediates and transition states are required. Despite its popularity, density functional theory (DFT) often fails to…

Chemical Physics · Physics 2016-06-23 Gregor N. Simm , Markus Reiher

The random feature method (RFM) constructs approximation spaces by initializing features from generic distributions, which provides universal approximation properties to solve general partial differential equations. However, such standard…

Numerical Analysis · Mathematics 2026-02-04 Qianxing Jia , Dong Wang

Coarse-grained (CG) molecular simulations have become a standard tool to study molecular processes on time- and length-scales inaccessible to all-atom simulations. Parameterizing CG force fields to match all-atom simulations has mainly…

Computational Physics · Physics 2023-02-07 Jonas Köhler , Yaoyi Chen , Andreas Krämer , Cecilia Clementi , Frank Noé

In our previous papers we have described efficient and reliable methods of generation of representative volume elements (RVE) perfectly suitable for analysis of composite materials via stochastic homogenization. In this paper we profit from…

Computational Engineering, Finance, and Science · Computer Science 2015-04-10 Vladimir Salnikov , Sophie Lemaitre , Daniel Choï , Philippe Karamian-Surville

Application of Genetic Algorithm (GA) for determination of parameters of an analytical representation of diatomic molecule potential is presented. GA can be used for finding potential characteristics of an electronic energy state which can…

Chemical Physics · Physics 2020-05-12 Tomasz Urbanczyk , Jaroslaw Koperski

Machine learning has emerged as a powerful tool for predicting molecular properties in chemical reaction networks with reduced computational cost. However, accurately predicting energies of transition state (TS) structures remains a…

Chemical Physics · Physics 2025-04-29 Stefan Gugler , Markus Reiher

Computational prediction of enzyme mechanism and protein function requires accurate physics-based models and suitable sampling. We discuss recent advances in large-scale quantum mechanical (QM) modeling of biochemical systems that have…

Chemical Physics · Physics 2021-05-28 Vyshnavi Vennelakanti , Azadeh Nazemi , Rimsha Mehmood , Adam H. Steeves , Heather J. Kulik

Feature selection is generally used as one of the most important preprocessing techniques in machine learning, as it helps to reduce the dimensionality of data and assists researchers and practitioners in understanding data. Thereby, by…

Machine Learning · Computer Science 2021-04-26 Yiwen Liao , Raphaël Latty , Bin Yang

The absence of compelling theoretical model requires the parameterizing the dark energy to probe its properties. The parametrization of the equation of state of the dark energy is a common method. We explore the theoretical optimization of…

Cosmology and Nongalactic Astrophysics · Physics 2014-03-11 Seokcheon Lee