Related papers: Expected performance of the TT-PET scanner

The TT-PET collaboration is developing an MRI-compatible small animal PET scanner in which the sensitive element is a monolithic silicon pixel ASIC targeting 30 ps RMS time resolution. The photon-detection technique is based on a stack of…

The TT-PET collaboration is developing a small animal TOF-PET scanner based on monolithic silicon pixel sensors in SiGe BiCMOS technology. The demonstrator chip, a small-scale version of the final detector ASIC, consists of a 3 x 10 pixel…

Time-of-flight measurement is an important advancement in PET scanners to improve image reconstruction with a lower delivered radiation dose. This article describes the monolithic ASIC for the TT-PET project, a novel idea for a…

The TT-PET collaboration is developing a PET scanner for small animals with 30 ps time-of-flight resolution and sub-millimetre 3D detection granularity. The sensitive element of the scanner is a monolithic silicon pixel detector based on…

The measurement of the time of flight of the two 511 keV gammas recorded in coincidence in a PET scanner provides an effective way of reducing the random background and therefore increases the scanner sensitivity, provided that the…

This paper describes the data acquisition and trigger system of the Thin Time-of-flight PET (TT-PET) scanner. The system is designed to read out in the order of 1000 pixel sensors used in the scanner and to provide a reference timing signal…

In this work, we present modeling and imaging performance of a dual panel limited-angle TOF-PET system for intraoperative surgical applications using GATE monte carlo toolkit. Several detector parameters such as detector pixel dimensions,…

In positron emission tomography (PET), time-of-flight (TOF) information localizes source positions along lines of response. Cherenkov-radiator-integrated microchannel-plate photomultiplier tubes have achieved 30 ps TOF resolution,…

The purpose of this study was to show how advanced concepts of compact, lossless and "Time Of Flight" (TOF) capable electronics similar to those foreseen for the LHC and ILC experiments could be fairly and easily transferred to the medical…

In this paper we use detailed Monte Carlo simulations to demonstrate that liquid xenon (LXe) can be used to build a Cherenkov-based TOF-PET, with an intrinsic coincidence resolving time (CRT) in the vicinity of 10 ps. This extraordinary…

PET is a functional imaging method that visualizes metabolic processes. TOF information can be derived from coincident detector signals and incorporated into image reconstruction to enhance the SNR. PET detectors are typically assessed by…

All of the present methods for calibration and monitoring of TOF-PET scanner detectors utilize radioactive isotopes such as e.g. $^{22}$Na or $^{68}$Ge, which are placed or rotate inside the scanner. In this article we describe a novel…

The growing interest in human-grade total body positron emission tomography (PET) systems has also application in small animal research. Due to the existing limitations in human-based studies involving drug development and novel treatment…

In this paper we prove that the choice of a suitable treatment of the scintillator surfaces, along with suitable photodetectors electronics and specific algorithms for raw data analysis, allow to achieve an optimal tradeoff between energy,…

The aim of this work is to show the potential capabilities of monolithic crystals coupled to large SiPM arrays, to be considered as detector blocks for PET scanners enabling Time Of Flight (TOF) capabilities. Monolithic blocks allow one to…

Nowadays, in Positron Emission Tomography (PET) systems, a Time of Flight information is used to improve the image reconstruction process. In Time of Flight PET (TOF-PET), fast detectors are able to measure the difference in the arrival…

Total-Body PET (TB-PET) scanners represent a significant advancement in medical diagnostics, exemplified by the uEXPLORER, the world's first TB-PET system with an axial span of 194 cm, which exhibits exceptional sensitivity and spatial…

Positron Emission Tomography (PET) using time-of-flight information, which can greatly improve the quality of the reconstructed image, has recently become an exciting topic. In this work, 3.2mm*3.2mm*25mm finger-like LYSO crystals were used…

Two major challenges in time-of-flight positron emission tomography (TOF-PET) are low spatial resolution and high radioactive dose to the patient, both of which result from limitations in detection technology rather than fundamental…

The foreseen CaLIPSO Positron Emission Tomography (PET) scanner is expected to yield simultaneously a fine image resolution, about 1 mm$^3$, and a high contrast. In this paper we present results of simulations for the full CaLIPSO PET…