Related papers: Interactive X-ray and proton therapy training and …
Cancer pathology is unique to a given individual, and developing personalized diagnostic and treatment protocols are a primary concern. Mathematical modeling and simulation is a promising approach to personalized cancer medicine. Yet, the…
Objective: The aim of this work is to investigate the feasibility of the Jagiellonian Positron Emission Tomography (J-PET) scanner for intra-treatment proton beam range monitoring. Approach: The Monte Carlo simulation studies with GATE and…
Chest computed tomography (CT) imaging adds valuable insight in the diagnosis and management of pulmonary infectious diseases, like tuberculosis (TB). However, due to the cost and resource limitations, only X-ray images may be available for…
Radiotherapy (RT) planning is complex, subjective, and time-intensive. Advances with artificial intelligence (AI) promise to improve its precision and efficiency, but progress is often limited by the scarcity of large, standardized…
A novel dose calculation approach was designed based on the application of LSTM network that processes the 3D patient/phantom geometry as a sequence of 2D computed tomography input slices yielding a corresponding sequence of 2D slices that…
Since the Radon transform (RT) consists in a line integral function, some modeling assumptions are made on Computed Tomography (CT) system, making image reconstruction analytical methods, such as Filtered Backprojection (FBP), sensitive to…
Radiation Therapy (XRT) is one of the most common cancer treatment methods. In this paper, a new mathematical model is proposed for the population dynamics of heterogeneous tumor cells following external beam radiation treatment. According…
It has been known for about sixty years that proton and heavy ion therapy is a very powerful radiation procedure for treating tumours. It has an innate ability to irradiate tumours with greater doses and spatial selectivity compared with…
Purpose: We present a framework for robust automated treatment planning using machine learning, comprising scenario-specific dose prediction and robust dose mimicking. Methods: The scenario dose prediction pipeline is divided into the…
In this work, we report on the advantageous aspects of the i-TED Compton imager for proton-range monitoring, based on the results of the first Monte Carlo study of its applicability to this field. i-TED is an array of Compton cameras, that…
Uncertainties in the proton range in tissue during proton therapy limit the precision in treatment delivery. These uncertainties result in expanded treatment margins, thereby increasing radiation dose to healthy tissue. Real-time range…
Advanced navigation techniques in image-guided interventions and surgical robotics require the rapid and precise alignment of 3D preoperative volumes (e.g., CT, MRI) to 2D intraoperative images (e.g., X-ray fluoroscopy). However, existing…
With the continued evolution of modern radiation therapy towards high precision delivery of high therapeutic doses to the tumour while optimally sparing surrounding healthy tissue, imaging becomes a crucial component to identify the…
Radiation Treatment Planning (RTP) is the process of planning the appropriate external beam radiotherapy to combat cancer in human patients. RTP is a complex and compute-intensive task, which often takes a long time (several hours) to…
Northern Illinois University in collaboration with Fermi National Accelerator Laboratory (FNAL) and Delhi University has been designing and building a proton CT scanner for applications in proton treatment planning. The Phase II proton CT…
We present a novel application of Tensor Network methods in cancer treatment as a potential tool to solve the dose optimization problem in radiotherapy. In particular, the Intensity-Modulated Radiation Therapy (IMRT) technique - that allows…
Adaptive Radiation Therapy (ART) was developed based on Image-guided Radiation Therapy (IGRT) and it is the trend of photon radiation therapy. To get a better use of Cone Beam CT (CBCT) images for ART, the CBCT system model was established…
Prostate brachytherapy involves implanting radioactive seeds (I125 for instance) permanently in the gland for the treatment of localized prostate cancers, e.g., cT1c-T2a N0 M0 with good prognostic factors. Treatment planning and seed…
Radiotherapy is a crucial cancer treatment that demands precise planning to balance tumor eradication and preservation of healthy tissue. Traditional treatment planning (TP) is iterative, time-consuming, and reliant on human expertise,…
Proton therapy offers superior organ-at-risk sparing but is highly sensitive to anatomical changes, making accurate deformable image registration (DIR) across longitudinal CT scans essential. Conventional DIR methods are often too slow for…