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Compliant environments can mediate interactions between mechanically active cells like fibroblasts. Starting with a phenomenological model for the behaviour of single cells, we use extensive Monte Carlo simulations to predict non-trivial…

Soft Condensed Matter · Physics 2007-05-23 I. B. Bischofs , U. S. Schwarz

Lattice defects in crystalline materials create long-range elastic fields which can be modelled on the atomistic scale using an infinite system of discrete nonlinear force balance equations. Starting with these equations, this work…

Analysis of PDEs · Mathematics 2022-08-10 Julian Braun , Thomas Hudson , Christoph Ortner

Elastic systems that are spatially heterogeneous in their mechanical response pose special challenges for molecular simulations. Standard methods for sampling thermal fluctuations of a system's size and shape proceed through a series of…

Materials Science · Physics 2015-05-13 Sander Pronk , Phillip L. Geissler

In this paper homogenization of a mathematical model for plant tissue biomechanics is presented. The microscopic model constitutes a strongly coupled system of reaction-diffusion-convection equations for chemical processes in plant cells,…

Analysis of PDEs · Mathematics 2017-08-24 Andrey Piatnitski , Mariya Ptashnyk

The organization of live cells to tissues is associated with the mechanical interaction between cells, which is mediated through their elastic environment. We model cells as spherical active force dipoles surrounded by an infinite elastic…

Biological Physics · Physics 2017-06-08 Roman Golkov , Yair Shokef

Flexoelectricity is characterised by the coupling of the gradient of the deformation and the electrical polarization in a dielectric material. A novel micromorphic approach is presented to accommodate the resulting higher-order gradient…

Classical Physics · Physics 2023-07-19 Andrew McBride , Denis Davydov , Paul Steinmann

Animal cells in tissues are supported by biopolymer matrices, which typically exhibit highly nonlinear mechanical properties. While the linear elasticity of the matrix can significantly impact cell mechanics and functionality, it remains…

A macroscopic mesoscopic, deterministic stochastic coupling strategy is proposed to accelerate the direct simulation Monte Carlo (DSMC) method for chemical reaction. First, a macroscopic synthetic equation is formulated by integrating…

Computational Physics · Physics 2026-05-14 Hong Deng , Liyan Luo , Lei Wu

In this paper, a two-scale approach for elastic shape optimization of fine-scale structures in additive manufacturing is investigated. To this end, a free material optimization is performed on the macro-scale using elasticity tensors in a…

Numerical Analysis · Mathematics 2022-07-28 Sergio Conti , Martin Rumpf , Stefan Simon

We propose a three dimensional mechanical model of embryonic tissue dynamics. Mechanically coupled adherent cells are represented as particles interconnected with elastic beams which can exert non-central forces and torques. Tissue…

Biological Physics · Physics 2015-06-22 Andras Czirok , Dona Greta Isai

A direct summation method for the Madelung constant calculation is presented where a crystal lattice is constructed from linear arrays of charges or axial multipoles. An array is designed to have vanishing low order electric moments such…

Materials Science · Physics 2025-03-18 Joven V. Calara , Jan D. Miller

Viscoelastic surface rheology plays an important role in multiphase systems. A typical example is the actin cortex which surrounds most animal cells. It shows elastic properties for short time scales and behaves viscous for longer time…

Fluid Dynamics · Physics 2021-06-01 Eloy de Kinkelder , Leonard Sagis , Sebastian Aland

Background: Calculation of the electric field induced by transcranial magnetic stimulation (TMS) in the brain requires accurate models of the stimulation coils. Reconstructing models from the measured magnetic fields of coils so far worked…

Other Quantitative Biology · Quantitative Biology 2021-12-30 Kristoffer Hougaard Madsen , Maria Drakaki , Axel Thielscher

The particle-in-cell approach has proven effective at modeling neutron star and black hole magnetospheres from first principles, but global simulations are plagued with an unrealistically small separation between the scales where…

High Energy Astrophysical Phenomena · Physics 2024-10-09 Adrien Soudais , Benoît Cerutti , Ioannis Contopoulos

We propose a method for the description and simulation of the nonlinear dynamics of slender structures modeled as Cosserat rods. It is based on interpreting the strains and the generalized velocities of the cross sections as basic variables…

Classical Physics · Physics 2022-10-11 G. G. Giusteri , E. Miglio , N. Parolini , M. Penati , R. Zambetti

Micropatterned substrates are often used to standardize cell experiments and to quantitatively study the relation between cell shape and function. Moreover, they are increasingly used in combination with traction force microscopy on soft…

Cell Behavior · Quantitative Biology 2015-06-19 Philipp J. Albert , Ulrich S. Schwarz

Starting from the random phase approximation for the weakly coupled multiband tightly-bounded electron systems, we calculate the dielectric matrix in terms of intraband and interband transitions. The advantages of this representation with…

Condensed Matter · Physics 2016-08-31 P. Zupanovic , A. Bjelis , S. Barisic

We present kinematic simulations of a galactic dynamo model based on the large scale differential rotation and the small scale helical fluctuations due to supernova explosions. We report for the first time direct numerical simulations of…

Astrophysics of Galaxies · Physics 2009-11-13 Christophe Gissinger , Sebastien Fromang , Emmanuel Dormy

Physical experiments can characterize the elastic response of granular materials in terms of macroscopic state-variables, namely volume (packing) fraction and stress, while the microstructure is not accessible and thus neglected. Here, by…

Soft Condensed Matter · Physics 2015-06-16 Nishant Kumar , Stefan Luding , Vanessa Magnanimo

The evolution of large-scale magnetic fields in disk galaxies is investigated numerically. The gasdynamical simulations in a disk perturbed by spiral or bar potential are incorporated into the kinematic calculations of induction equations…

Astrophysics · Physics 2007-05-23 K. Otmianowska-Mazur , M. Chiba