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Timely diagnostics of microcirculatory system abnormalities which are the most severe diabetic complications, is a significant problem of modern health care. Functional abnormalities manifest themselves earlier than the structural one and…
Non-invasive measurement of the arterial blood speed gives rise to important healthinformation such as cardio output and blood supplies to vital organs. The magnitude andchange in arterial blood speed are key indicators of the health…
Methods of Computational Fluid Dynamics are applied to simulate pulsatile blood flow in human vessels and in the aortic arch. The non-Newtonian behaviour of the human blood is investigated in simple vessels of actual size. A detailed…
Laser Doppler holography was introduced as a full-field imaging technique to measure blood flow in the retina and choroid with an as yet unrivaled temporal resolution. We here investigate separating the different contributions to the power…
This study examined the flow rate in arteries using the modified Windkessel model, considering various models for blood pressure. An exact solution was derived using a Laplace transform method and the effects of blood pressure on the flow…
We report on local superficial blood flow monitoring in biological tissue from laser Doppler holographic imaging. In time averaging recording conditions, holography acts as a narrowband bandpass filter, which, combined with a frequency…
Laser Doppler holography is a planar blood flow imaging technique recently introduced in ophthalmology to image human retinal and choroidal blood flow non-invasively. Here we present a digital method based on the Doppler spectrum asymmetry…
Cerebral blood flow is a critical metric for cerebrovascular monitoring, with applications in stroke detection, brain injury evaluation, aging, and neurological disorders. Non-invasively measuring cerebral blood dynamics is challenging due…
We report on wide-field imaging of pulsatile motion induced by blood flow using heterodyne holographic interferometry on the thumb of a healthy volunteer, in real-time. Optical Doppler images were measured with green laser light by a…
Droplet microfluidics combined with optical detection has become a powerful approach for high-throughput single-cell assays, but these systems often face limited sensitivity and signal heterogeneity due to optical and geometrical…
Morphology of cardiovascular tissue is influenced by the unsteady behavior of the blood flow and vice versa. Therefore, the pathogenesis of several cardiovascular diseases is directly affected by the blood-flow dynamics. Understanding flow…
Stroke poses a significant global health threat, with millions affected annually, leading to substantial morbidity and mortality. Current stroke risk assessment for the general population relies on markers such as demographics, blood tests,…
Our research is related to the employment of photoplethysmography (PPG) and laser Doppler flowmetry (LDF) techniques (measuring the blood volume and flux, respectively) for the peripheral vascular system. We derive the governing equations…
We report on using a laser Doppler processing of Fourier-domain optical coherence tomography (OCT) data for the assessment of pulsatile blood flow in the choriocapillaris. Signal fluctuations in B-scans recorded at 2 kHz were analyzed by…
Cardiopulmonary resuscitation (CPR) is one of the essential tools to ensure oxygen supply during cardiac arrest. However, the precise effects of chest compression are not quantifiable to this day. This often results in a low quality of…
The influence of the phase fluctuation of the pump laser on the phase-correlation between the signal and idler modes of the output fields from as non-degenerate optical parametric oscillator operating above oscillation threshold was…
Blood pressure regulation is commonly addressed in terms of local mechanisms such as vascular resistance, compliance and neurohumoral control. However, the human vasculature encompasses multiple quasi-closed flow loops under both…
Background. Different mechanisms have been proposed to relate atrial fibrillation (AF) and coronary flow impairment, even in absence of relevant coronary artery disease (CAD). However, the underlying hemodynamics remains unclear. Aim of the…
Microcirculation of blood and oxygen transport play important roles in biological function of optic nerve and are directly affected by damages or pathologies. This work develops a multi-domain model for optic nerve, that includes important…
Pulsatile flow through compressed or defective blood vessels is a topic of fundamental importance in hemodynamics, particularly in cardiovascular research. This study examines flow dynamics within a tube with a bipolar cross section,…