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In electronic health records (EHRs), clustering patients and distinguishing disease subtypes are key tasks to elucidate pathophysiology and aid clinical decision-making. However, clustering in healthcare informatics is still based on…

Machine Learning · Computer Science 2026-04-09 Manar D. Samad , Yina Hou , Shrabani Ghosh

Artificial intelligence (AI) and deep learning techniques have gained significant attraction in recent years, owing to their remarkable capability of achieving high performance across a broad range of applications. However, a crucial…

Distributed, Parallel, and Cluster Computing · Computer Science 2023-07-03 Abdulrezzak Zekiye , Öznur Özkasap

Deep learning models exhibit state-of-the-art performance for many predictive healthcare tasks using electronic health records (EHR) data, but these models typically require training data volume that exceeds the capacity of most healthcare…

Machine Learning · Computer Science 2018-10-24 Edward Choi , Cao Xiao , Walter F. Stewart , Jimeng Sun

Personalized medication aims to tailor healthcare to individual patient characteristics. However, the heterogeneity of patient data across healthcare systems presents significant challenges to achieving accurate and effective personalized…

Artificial Intelligence · Computer Science 2024-12-10 Jiechao Gao , Yuangang Li

One of the key challenges of collaborative machine learning, without data sharing, is multimodal data heterogeneity in real-world settings. While Federated Learning (FL) enables model training across multiple clients, existing frameworks,…

Machine Learning · Computer Science 2025-10-16 Alejandro Guerra-Manzanares , Omar El-Herraoui , Michail Maniatakos , Farah E. Shamout

Data privacy constraints pose significant challenges for large-scale neuroimaging analysis, especially in multi-site functional magnetic resonance imaging (fMRI) studies, where site-specific heterogeneity leads to non-independent and…

Machine Learning · Computer Science 2025-09-26 Yipu Zhang , Chengshuo Zhang , Ziyu Zhou , Gang Qu , Hao Zheng , Yuping Wang , Hui Shen , Hongwen Deng

Can health entities collaboratively train deep learning models without sharing sensitive raw data? This paper proposes several configurations of a distributed deep learning method called SplitNN to facilitate such collaborations. SplitNN…

Machine Learning · Computer Science 2018-12-04 Praneeth Vepakomma , Otkrist Gupta , Tristan Swedish , Ramesh Raskar

Machine learning relies on the availability of a vast amount of data for training. However, in reality, most data are scattered across different organizations and cannot be easily integrated under many legal and practical constraints. In…

Machine Learning · Computer Science 2020-06-25 Yang Liu , Yan Kang , Chaoping Xing , Tianjian Chen , Qiang Yang

Federated Learning (FL) is a rising approach towards collaborative and privacy-preserving machine learning where large-scale medical datasets remain localized to each client. However, the issue of data heterogeneity among clients often…

Machine Learning · Computer Science 2024-10-01 Shuang Zeng , Pengxin Guo , Shuai Wang , Jianbo Wang , Yuyin Zhou , Liangqiong Qu

Federated learning (FL) is an effective solution to train machine learning models on the increasing amount of data generated by IoT devices and smartphones while keeping such data localized. Most previous work on federated learning assumes…

Machine Learning · Computer Science 2023-01-05 Othmane Marfoq , Giovanni Neglia , Laetitia Kameni , Richard Vidal

Federated continual learning (FCL) offers an emerging pattern to facilitate the applicability of federated learning (FL) in real-world scenarios, where tasks evolve dynamically and asynchronously across clients, especially in medical…

Machine Learning · Computer Science 2025-03-28 Xiaoming Qi , Jingyang Zhang , Huazhu Fu , Guanyu Yang , Shuo Li , Yueming Jin

Federated Learning (FL) has emerged as a transformative paradigm for distributed machine learning while preserving data privacy. However, existing approaches predominantly focus on model heterogeneity and aggregation techniques, largely…

Machine Learning · Computer Science 2025-09-23 Sajid Hussain , Muhammad Sohail , Nauman Ali Khan , Naima Iltaf , Ihtesham ul Islam

Federated learning (FL) enables distributed participants to collectively learn a strong global model without sacrificing their individual data privacy. Mainstream FL approaches require each participant to share a common network architecture…

Machine Learning · Computer Science 2021-07-28 Yiying Li , Wei Zhou , Huaimin Wang , Haibo Mi , Timothy M. Hospedales

Millions of patients suffer from rare diseases around the world. However, the samples of rare diseases are much smaller than those of common diseases. In addition, due to the sensitivity of medical data, hospitals are usually reluctant to…

Machine Learning · Computer Science 2021-12-30 Bingyang Chen , Tao Chen , Xingjie Zeng , Weishan Zhang , Qinghua Lu , Zhaoxiang Hou , Jiehan Zhou , Sumi Helal

When a deep learning model is trained sequentially on different datasets, it often forgets the knowledge learned from previous data, a problem known as catastrophic forgetting. This damages the model's performance on diverse datasets, which…

Federated Learning (FL) marks a transformative approach to distributed model training by combining locally optimized models from various clients into a unified global model. While FL preserves data privacy by eliminating centralized…

Machine Learning · Computer Science 2026-01-08 Pranab Sahoo , Ashutosh Tripathi , Sriparna Saha , Samrat Mondal

The widespread adoption of Electronic Health Record (EHR) systems in healthcare institutes has generated vast amounts of medical data, offering significant opportunities for improving healthcare services through deep learning techniques.…

Machine Learning · Computer Science 2024-01-23 Suhan Cui , Jiaqi Wang , Yuan Zhong , Han Liu , Ting Wang , Fenglong Ma

Histopathological tissue classification is a fundamental task in computational pathology. Deep learning-based models have achieved superior performance but centralized training with data centralization suffers from the privacy leakage…

Image and Video Processing · Electrical Eng. & Systems 2023-12-19 Tianpeng Deng , Yanqi Huang , Guoqiang Han , Zhenwei Shi , Jiatai Lin , Qi Dou , Zaiyi Liu , Xiao-jing Guo , C. L. Philip Chen , Chu Han

Privacy-sensitive data is stored in autonomous vehicles, smart devices, or sensor nodes that can move around with making opportunistic contact with each other. Federation among such nodes was mainly discussed in the context of federated…

Machine Learning · Computer Science 2022-10-10 Hideya Ochiai , Yuwei Sun , Qingzhe Jin , Nattanon Wongwiwatchai , Hiroshi Esaki

Federated Learning (FL) is a machine-learning approach enabling collaborative model training across multiple decentralized edge devices that hold local data samples, all without exchanging these samples. This collaborative process occurs…

Machine Learning · Computer Science 2024-01-02 Venkataraman Natarajan Iyer