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The development of statistical approaches for the joint modelling of the temporal changes of imaging, biochemical, and clinical biomarkers is of paramount importance for improving the understanding of neurodegenerative disorders, and for…

Applications · Statistics 2018-02-16 Marco Lorenzi , Maurizio Filippone , Daniel C. Alexander , Sebastien Ourselin

In a world with data that change rapidly and abruptly, it is important to detect those changes accurately. In this paper we describe an R package implementing a generalized version of an algorithm recently proposed by Hocking et al. [2020]…

Time-to-event models are commonly used to study associations between risk factors and disease outcomes in the setting of electronic health records (EHR). In recent years, focus has intensified on social determinants of health, highlighting…

Applications · Statistics 2025-11-26 Yueming Shen , Christian Pean , David Dunson , Samuel Berchuck

As current computing capabilities increase, modern machine learning and computer vision system tend to increase in complexity, mostly by means of larger models and advanced optimization strategies. Although often neglected, in many problems…

Image and Video Processing · Electrical Eng. & Systems 2024-06-07 Adrian Galdran , Miguel A. González Ballester

The real-world deployment of fully autonomous mobile robots depends on a robust SLAM (Simultaneous Localization and Mapping) system, capable of handling dynamic environments, where objects are moving in front of the robot, and changing…

Stochastic video prediction enables the consideration of uncertainty in future motion, thereby providing a better reflection of the dynamic nature of the environment. Stochastic video prediction methods based on image auto-regressive…

Computer Vision and Pattern Recognition · Computer Science 2024-04-18 Fei Cui , Jiaojiao Fang , Xiaojiang Wu , Zelong Lai , Mengke Yang , Menghan Jia , Guizhong Liu

We consider the testing and estimation of change-points -- locations where the distribution abruptly changes -- in a data sequence. A new approach, based on scan statistics utilizing graphs representing the similarity between observations,…

Methodology · Statistics 2015-02-18 Hao Chen , Nancy Zhang

Spatially and temporally varying coefficient (STVC) models are currently attracting attention as a flexible tool to explore the spatio-temporal patterns in regression coefficients. However, these models often struggle with balancing…

Methodology · Statistics 2025-01-07 Daisuke Murakami , Shinichiro Shirota , Seiji Kajita , Mami Kajita

Spatio-temporal point process (STPP) is a stochastic collection of events accompanied with time and space. Due to computational complexities, existing solutions for STPPs compromise with conditional independence between time and space,…

Machine Learning · Computer Science 2023-06-27 Yuan Yuan , Jingtao Ding , Chenyang Shao , Depeng Jin , Yong Li

Glaucoma is the leading cause of irreversible blindness worldwide and poses significant diagnostic challenges due to its reliance on subjective evaluation. However, recent advances in computer vision and deep learning have demonstrated the…

Image and Video Processing · Electrical Eng. & Systems 2023-08-01 Mona Ashtari-Majlan , Mohammad Mahdi Dehshibi , David Masip

Medical vision-language models (VLMs) have demonstrated unprecedented transfer capabilities and are being increasingly adopted for data-efficient image classification. Despite its growing popularity, its reliability aspect remains largely…

Computer Vision and Pattern Recognition · Computer Science 2025-06-24 Julio Silva-Rodríguez , Ismail Ben Ayed , Jose Dolz

Unlike conventional frame-based sensors, event-based visual sensors output information through spikes at a high temporal resolution. By only encoding changes in pixel intensity, they showcase a low-power consuming, low-latency approach to…

Computer Vision and Pattern Recognition · Computer Science 2019-03-19 Rohan Ghosh , Anupam Gupta , Siyi Tang , Alcimar Soares , Nitish Thakor

Missingness and measurement frequency are two sides of the same coin. How frequent should we measure clinical variables and conduct laboratory tests? It depends on many factors such as the stability of patient conditions, diagnostic…

Machine Learning · Computer Science 2024-02-16 Jiacheng Liu , Jaideep Srivastava

Multiple sclerosis is a chronic autoimmune disease that affects the central nervous system. Understanding multiple sclerosis progression and identifying the implicated brain structures is crucial for personalized treatment decisions.…

Identifying disease-indicative genes is critical for deciphering disease mechanisms and has attracted significant interest in biomedical research. Spatial transcriptomics offers unprecedented insights for the detection of disease-specific…

Methodology · Statistics 2024-09-05 Qicheng Zhao , Qihuang Zhang

Identifying and utilising various biomarkers for tracking Alzheimer's disease (AD) progression have received many recent attentions and enable helping clinicians make the prompt decisions. Traditional progression models focus on extracting…

Machine Learning · Computer Science 2023-11-08 Xulong Wang , Yu Zhang , Menghui Zhou , Tong Liu , Jun Qi , Po Yang

Glaucoma is a chronic visual disease that may cause permanent irreversible blindness. Measurement of the cup-to-disc ratio (CDR) plays a pivotal role in the detection of glaucoma in its early stage, preventing visual disparities. Therefore,…

Computer Vision and Pattern Recognition · Computer Science 2023-03-10 Rukhshanda Hussain , Hritam Basak

Spatial confounding is how is called the confounding between fixed and spatial random effects. It has been widely studied and it gained attention in the past years in the spatial statistics literature, as it may generate unexpected results…

Objective: (1) To assess whether ONH biomechanics improves prediction of three progressive visual field loss patterns in glaucoma; (2) to use explainable AI to identify strain-sensitive ONH regions contributing to these predictions.…

A variety of vision ailments are associated with geographic atrophy (GA) in the foveal region of the eye. In current clinical practice, the ophthalmologist manually detects potential presence of such GA based on fundus autofluorescence…