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The genetic information that dictates the structure and function of all life forms is encoded in the DNA. In 1953, Watson and Crick first presented the double helical structure of a DNA molecule. Their findings unearthed the desire to…

Genomics · Quantitative Biology 2023-05-16 Olaitan Akintunde , Trichina Tucker , Valerie J. Carabetta

Given a query result of a big database, why-provenance can be used to calculate the necessary part of this database, consisting of so-called witnesses. If this database consists of personal data, privacy protection has to prevent the…

Databases · Computer Science 2021-01-13 Tanja Auge , Nic Scharlau , Andreas Heuer

Privacy-preserving data splitting is a technique that aims to protect data privacy by storing different fragments of data in different locations. In this work we give a new combinatorial formulation to the data splitting problem. We see the…

Cryptography and Security · Computer Science 2018-01-19 Oriol Farràs , Jordi Ribes-González , Sara Ricci

Feature selection is the process of sieving features, in which informative features are separated from the redundant and irrelevant ones. This process plays an important role in machine learning, data mining and bioinformatics. However,…

Cryptography and Security · Computer Science 2020-08-19 Javad Rahimipour Anaraki , Saeed Samet

We propose generative neural network methods to generate DNA sequences and tune them to have desired properties. We present three approaches: creating synthetic DNA sequences using a generative adversarial network; a DNA-based variant of…

Machine Learning · Computer Science 2017-12-19 Nathan Killoran , Leo J. Lee , Andrew Delong , David Duvenaud , Brendan J. Frey

Machine learning techniques based on neural networks are achieving remarkable results in a wide variety of domains. Often, the training of models requires large, representative datasets, which may be crowdsourced and contain sensitive…

Machine Learning · Statistics 2018-12-21 Martín Abadi , Andy Chu , Ian Goodfellow , H. Brendan McMahan , Ilya Mironov , Kunal Talwar , Li Zhang

In recent years, it has been claimed that releasing accurate statistical information on a database is likely to allow its complete reconstruction. Differential privacy has been suggested as the appropriate methodology to prevent these…

Cryptography and Security · Computer Science 2023-01-25 Krishnamurty Muralidhar , Josep Domingo-Ferrer

As machine learning becomes a practice and commodity, numerous cloud-based services and frameworks are provided to help customers develop and deploy machine learning applications. While it is prevalent to outsource model training and…

Cryptography and Security · Computer Science 2018-07-16 Tianwei Zhang , Zecheng He , Ruby B. Lee

The process of DNA-based data storage (DNA storage for short) can be mathematically modelled as a communication channel, termed DNA storage channel, whose inputs and outputs are sets of unordered sequences. To design error correcting codes…

Information Theory · Computer Science 2020-06-11 Wentu Song , Kui Cai , Kees A. Schouhamer Immink

Recent advances in score-based generative models have led to a huge spike in the development of downstream applications using generative models ranging from data augmentation over image and video generation to anomaly detection. Despite…

Computer Vision and Pattern Recognition · Computer Science 2023-06-05 Mischa Dombrowski , Bernhard Kainz

Due to its longevity and enormous information density, DNA is an attractive medium for archival data storage. Thanks to rapid technological advances, DNA storage is becoming practically feasible, as demonstrated by a number of experimental…

Information Theory · Computer Science 2022-11-11 Ilan Shomorony , Reinhard Heckel

Deep learning models have demonstrated superior performance in several application problems, such as image classification and speech processing. However, creating a deep learning model using health record data requires addressing certain…

Machine Learning · Computer Science 2021-12-14 Amirsina Torfi , Edward A. Fox , Chandan K. Reddy

Private closeness testing asks to decide whether the underlying probability distributions of two sensitive datasets are identical or differ significantly in statistical distance, while guaranteeing (differential) privacy of the data. As in…

Data Structures and Algorithms · Computer Science 2023-09-14 Clément L. Canonne , Yucheng Sun

Privacy preservation is an important issue in today's context of extreme penetration of internet and mobile technologies. It is more important in the case of Wireless Sensor Networks (WSNs) where collected data often requires in-network…

Cryptography and Security · Computer Science 2016-11-17 Arijit Ukil

Nanopore sequencing is an emerging new technology for sequencing DNA, which can read long fragments of DNA (~50,000 bases) in contrast to most current short-read sequencing technologies which can only read hundreds of bases. While nanopore…

Information Theory · Computer Science 2018-02-20 Wei Mao , Suhas Diggavi , Sreeram Kannan

Sequential querying of differentially private mechanisms degrades the overall privacy level. In this paper, we answer the fundamental question of characterizing the level of overall privacy degradation as a function of the number of queries…

Data Structures and Algorithms · Computer Science 2015-12-08 Peter Kairouz , Sewoong Oh , Pramod Viswanath

In this review paper, we delve into the nascent field of molecular data storage, focusing on system implementations and code constructions. We start by providing an overview of basic concepts in synthetic and computational biology.…

Emerging Technologies · Computer Science 2023-10-10 Olgica Milenkovic , Chao Pan

Training machine learning models based on neural networks requires large datasets, which may contain sensitive information. The models, however, should not expose private information from these datasets. Differentially private SGD [DP-SGD]…

Machine Learning · Computer Science 2024-09-26 Francisco Aguilera-Martínez , Fernando Berzal

The Domain Name System (DNS) was created to resolve the IP addresses of the web servers to easily remembered names. When it was initially created, security was not a major concern; nowadays, this lack of inherent security and trust has…

Cryptography and Security · Computer Science 2020-08-17 Pavlos Papadopoulos , Nikolaos Pitropakis , William J. Buchanan , Owen Lo , Sokratis Katsikas

In this work, we propose a novel framework for privacy-preserving client-distributed machine learning. It is motivated by the desire to achieve differential privacy guarantees in the local model of privacy in a way that satisfies all…

Cryptography and Security · Computer Science 2018-10-12 Vasyl Pihur , Aleksandra Korolova , Frederick Liu , Subhash Sankuratripati , Moti Yung , Dachuan Huang , Ruogu Zeng