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In this paper, we investigate dynamic feature selection within multivariate time-series scenario, a common occurrence in clinical prediction monitoring where each feature corresponds to a bio-test result. Many existing feature selection…

Machine Learning · Computer Science 2024-05-31 Yutong Chen , Jiandong Gao , Ji Wu

This paper investigates how to incorporate expert observations (without explicit information on expert actions) into a deep reinforcement learning setting to improve sample efficiency. First, we formulate an augmented policy loss combining…

Machine Learning · Computer Science 2025-02-28 Erhan Can Ozcan , Vittorio Giammarino , James Queeney , Ioannis Ch. Paschalidis

Guideline-based treatment for sepsis and septic shock is difficult because sepsis is a disparate range of life-threatening organ dysfunctions whose pathophysiology is not fully understood. Early intervention in sepsis is crucial for patient…

Machine Learning · Computer Science 2021-09-24 Ran Liu , Joseph L. Greenstein , James C. Fackler , Jules Bergmann , Melania M. Bembea , Raimond L. Winslow

Model-based reinforcement learning (MBRL) provides a way to learn a transition model of the environment, which can then be used to plan personalized policies for different patient cohorts and to understand the dynamics involved in the…

Machine Learning · Computer Science 2024-11-22 Abhishek Sharma , Sonali Parbhoo , Omer Gottesman , Finale Doshi-Velez

We propose a model to tackle classification tasks in the presence of very little training data. To this aim, we approximate the notion of exact match with a theoretically sound mechanism that computes a probability of matching in the input…

Offline reinforcement learning (RL) aims to learn an optimal policy from pre-collected data. However, it faces challenges of distributional shift, where the learned policy may encounter unseen scenarios not covered in the offline data.…

Machine Learning · Computer Science 2025-05-27 Jin Zhu , Xin Zhou , Jiaang Yao , Gholamali Aminian , Omar Rivasplata , Simon Little , Lexin Li , Chengchun Shi

Comorbid chronic conditions are common among people with type 2 diabetes. We developed an Artificial Intelligence algorithm, based on Reinforcement Learning (RL), for personalized diabetes and multi-morbidity management with strong…

Computers and Society · Computer Science 2020-11-05 Hua Zheng , Ilya O. Ryzhov , Wei Xie , Judy Zhong

Real-world decision-making tasks are generally complex, requiring trade-offs between multiple, often conflicting, objectives. Despite this, the majority of research in reinforcement learning and decision-theoretic planning either assumes…

A learning task, understood as the problem of fitting a parametric model from supervised data, fundamentally requires the dataset to be large enough to be representative of the underlying distribution of the source. When data is limited,…

Machine Learning · Computer Science 2025-11-18 Leopoldo Agorio , Juan Cerviño , Miguel Calvo-Fullana , Alejandro Ribeiro , Juan Andrés Bazerque

This research paper outlines the development and implementation of a novel Clinical Decision Support System (CDSS) that integrates AI predictive modeling with medical knowledge bases. It utilizes the quantifiable information elements in lab…

Artificial Intelligence · Computer Science 2026-03-17 Muhammad Hammad Maqsood , Mubashir Sajid , Khubaib Ahmed , Muhammad Usamah Shahid , Muddassar Farooq

Clinical abnormality grounding for rare diseases is often hindered by data scarcity, making supervised fine-tuning impractical and single-pass inference highly unstable. We propose Dynamic Decision Learning (DDL), a framework that enables…

Computation and Language · Computer Science 2026-04-29 Jun Li , Mingxuan Liu , Jiazhen Pan , Che Liu , Wenjia Bai , Cosmin I. Bercea , Julia A. Schnabel

The symptom checking systems inquire users for their symptoms and perform a rapid and affordable medical assessment of their condition. The basic symptom checking systems based on Bayesian methods, decision trees, or information gain…

Computation and Language · Computer Science 2022-06-03 Aleksandr Nesterov , Bulat Ibragimov , Dmitriy Umerenkov , Artem Shelmanov , Galina Zubkova , Vladimir Kokh

Randomized experiments (a.k.a. A/B tests) are a powerful tool for estimating treatment effects, to inform decisions making in business, healthcare and other applications. In many problems, the treatment has a lasting effect that evolves…

Machine Learning · Computer Science 2022-10-17 Ziyang Tang , Yiheng Duan , Stephanie Zhang , Lihong Li

Rare diseases affect millions worldwide but often face limited research focus due to their low prevalence. This results in prolonged diagnoses and a lack of approved therapies. Recent advancements in Large Language Models (LLMs) have shown…

Computation and Language · Computer Science 2024-10-28 Lang Cao , Jimeng Sun , Adam Cross

Predictive uncertainty-a model's self awareness regarding its accuracy on an input-is key for both building robust models via training interventions and for test-time applications such as selective classification. We propose a novel…

Machine Learning · Computer Science 2024-01-04 Nishant Jain , Karthikeyan Shanmugam , Pradeep Shenoy

We introduce a simple but effective method for managing risk in model-based reinforcement learning with trajectory sampling that involves probabilistic safety constraints and balancing of optimism in the face of epistemic uncertainty and…

Machine Learning · Computer Science 2023-09-12 Marin Vlastelica , Sebastian Blaes , Cristina Pineri , Georg Martius

Despite the impressive advances achieved using deep learning for functional brain activity analysis, the heterogeneity of functional patterns and the scarcity of imaging data still pose challenges in tasks such as identifying neurological…

Image and Video Processing · Electrical Eng. & Systems 2025-05-30 Wenhui Cui , Haleh Akrami , Anand A. Joshi , Richard M. Leahy

Assessment of model fitness is a key part of machine learning. The standard paradigm is to learn models by minimizing a chosen loss function averaged over training data, with the aim of achieving small losses on future data. In this paper,…

Machine Learning · Statistics 2023-10-17 Ludvig Hult , Dave Zachariah , Petre Stoica

Background: Clinical diagnosis is typically reached by following a series of steps recommended by guidelines authored by colleges of experts. Accordingly, guidelines play a crucial role in rationalizing clinical decisions but suffer from…

Machine Learning · Computer Science 2024-04-10 Lillian Muyama , Antoine Neuraz , Adrien Coulet

In order for reinforcement learning techniques to be useful in real-world decision making processes, they must be able to produce robust performance from limited data. Deep policy optimization methods have achieved impressive results on…

Machine Learning · Computer Science 2020-12-22 James Queeney , Ioannis Ch. Paschalidis , Christos G. Cassandras