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Accurate brain tumor segmentation from MRI is vital for diagnosis and treatment planning. Although Monte Carlo (MC) Dropout is widely used to estimate model uncertainty, the effectiveness of variance-based uncertainty - computed as…

Machine Learning · Computer Science 2026-05-28 Saumya B

In this paper, we develop a metric designed to assess and rank uncertainty measures for the task of brain tumour sub-tissue segmentation in the BraTS 2019 sub-challenge on uncertainty quantification. The metric is designed to: (1) reward…

Image and Video Processing · Electrical Eng. & Systems 2020-06-02 Raghav Mehta , Angelos Filos , Yarin Gal , Tal Arbel

Image reconstruction methods based on deep neural networks have shown outstanding performance, equalling or exceeding the state-of-the-art results of conventional approaches, but often do not provide uncertainty information about the…

Computer Vision and Pattern Recognition · Computer Science 2020-12-01 Riccardo Barbano , Željko Kereta , Chen Zhang , Andreas Hauptmann , Simon Arridge , Bangti Jin

Deep Learning (DL) holds great promise in reshaping the industry owing to its precision, efficiency, and objectivity. However, the brittleness of DL models to noisy and out-of-distribution inputs is ailing their deployment in sensitive…

Image and Video Processing · Electrical Eng. & Systems 2025-10-03 Giuseppina Carannante , Nidhal C. Bouaynaya , Dimah Dera , Hassan M. Fathallah-Shaykh , Ghulam Rasool

Uncertainty estimation, which provides a means of building explainable neural networks for medical imaging applications, have mostly been studied for single deep learning models that focus on a specific task. In this paper, we propose a…

Computer Vision and Pattern Recognition · Computer Science 2023-10-02 Leonhard F. Feiner , Martin J. Menten , Kerstin Hammernik , Paul Hager , Wenqi Huang , Daniel Rueckert , Rickmer F. Braren , Georgios Kaissis

Deep neural networks (DNNs) have achieved state-of-the-art performances in many important domains, including medical diagnosis, security, and autonomous driving. In these domains where safety is highly critical, an erroneous decision can…

Machine Learning · Computer Science 2019-06-12 Aryan Mobiny , Hien V. Nguyen , Supratik Moulik , Naveen Garg , Carol C. Wu

Brain segmentation is a fundamental first step in neuroimage analysis. In the case of fetal MRI, it is particularly challenging and important due to the arbitrary orientation of the fetus, organs that surround the fetal head, and…

Current state-of-the-art deep learning segmentation methods have not yet made a broad entrance into the clinical setting in spite of high demand for such automatic methods. One important reason is the lack of reliability caused by models…

Computer Vision and Pattern Recognition · Computer Science 2019-06-18 Jörg Sander , Bob D. de Vos , Jelmer M. Wolterink , Ivana Išgum

Quantitative analysis of brain tumors is critical for clinical decision making. While manual segmentation is tedious, time consuming and subjective, this task is at the same time very challenging to solve for automatic segmentation methods.…

Computer Vision and Pattern Recognition · Computer Science 2018-03-01 Fabian Isensee , Philipp Kickingereder , Wolfgang Wick , Martin Bendszus , Klaus H. Maier-Hein

To safely deploy deep learning models in the clinic, a quality assurance framework is needed for routine or continuous monitoring of input-domain shift and the models' performance without ground truth contours. In this work, cardiac…

Image and Video Processing · Electrical Eng. & Systems 2023-05-22 Xiyao Jin , Yao Hao , Jessica Hilliard , Zhehao Zhang , Maria A. Thomas , Hua Li , Abhinav K. Jha , Geoffrey D. Hugo

We propose a novel method for closed-form predictive distribution modeling with neural nets. In quantifying prediction uncertainty, we build on Evidential Deep Learning, which has been impactful as being both simple to implement and giving…

Machine Learning · Statistics 2021-01-22 Manuel Haussmann , Sebastian Gerwinn , Melih Kandemir

Deep Bayesian neural network has aroused a great attention in recent years since it combines the benefits of deep neural network and probability theory. Because of this, the network can make predictions and quantify the uncertainty of the…

Machine Learning · Computer Science 2019-03-25 Yikuan Li , Yajie Zhu

In this paper, we propose a novel mutual consistency network (MC-Net+) to effectively exploit the unlabeled data for semi-supervised medical image segmentation. The MC-Net+ model is motivated by the observation that deep models trained with…

Computer Vision and Pattern Recognition · Computer Science 2022-07-05 Yicheng Wu , Zongyuan Ge , Donghao Zhang , Minfeng Xu , Lei Zhang , Yong Xia , Jianfei Cai

Deep neural network (DNN) models have achieved state-of-the-art predictive accuracy in a wide range of supervised learning applications. However, accurately quantifying the uncertainty in DNN predictions remains a challenging task. For…

Machine Learning · Computer Science 2022-06-14 Daiwei Zhang , Tianci Liu , Jian Kang

Uncertainty quantification for deep learning is a challenging open problem. Bayesian statistics offer a mathematically grounded framework to reason about uncertainties; however, approximate posteriors for modern neural networks still…

Machine Learning · Statistics 2020-01-23 Nicolas Brosse , Carlos Riquelme , Alice Martin , Sylvain Gelly , Éric Moulines

Medical images are often used to detect and characterize pathology and disease; however, automatically identifying and segmenting pathology in medical images is challenging because the appearance of pathology across diseases varies widely.…

Image and Video Processing · Electrical Eng. & Systems 2020-02-19 Jacob C. Reinhold , Yufan He , Shizhong Han , Yunqiang Chen , Dashan Gao , Junghoon Lee , Jerry L. Prince , Aaron Carass

Medical image segmentation is critical for disease diagnosis and treatment assessment. However, concerns regarding the reliability of segmentation regions persist among clinicians, mainly attributed to the absence of confidence assessment,…

Image and Video Processing · Electrical Eng. & Systems 2025-09-12 Ke Zou , Yidi Chen , Ling Huang , Xuedong Yuan , Xiaojing Shen , Meng Wang , Rick Siow Mong Goh , Yong Liu , Huazhu Fu

NeuroNet is a deep convolutional neural network mimicking multiple popular and state-of-the-art brain segmentation tools including FSL, SPM, and MALPEM. The network is trained on 5,000 T1-weighted brain MRI scans from the UK Biobank Imaging…

Computer Vision and Pattern Recognition · Computer Science 2018-06-13 Martin Rajchl , Nick Pawlowski , Daniel Rueckert , Paul M. Matthews , Ben Glocker

The Computer_Aided Diagnosis (CAD) systems facilitate accurate diagnosis of diseases. The development of CADs by leveraging third generation neural network, namely, Spiking Neural Network (SNN), is essential to utilize of the benefits of…

Image and Video Processing · Electrical Eng. & Systems 2025-04-28 Mohaddeseh Chegini , Ali Mahloojifar

Automated segmentation of distinct tumor regions is critical for accurate diagnosis and treatment planning in pediatric brain tumors. This study evaluates the efficacy of the Multi-Planner U-Net (MPUnet) approach in segmenting different…

Image and Video Processing · Electrical Eng. & Systems 2024-01-15 Sumit Pandey , Satyasaran Changdar , Mathias Perslev , Erik B Dam
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