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Surface-enhanced Raman spectroscopy is a powerful and versatile sensing method with a detection limit down to the single molecule level. In this article, we demonstrate how topology optimization (TopOpt) can be used for designing surface…

Mesoscale and Nanoscale Physics · Physics 2021-08-25 Ying Pan , Rasmus E. Christiansen , Jerome Michon , Juejun Hu , Steven G. Johnson

We demonstrate waveguide-coupled titanium dioxide (TiO2) racetrack resonators with loaded quality factors of 2x10^4 for the visible wavelengths. The structures were fabricated in sputtered TiO2 thin films on oxidized silicon substrates…

Light scattering limits the penetration depth of non-invasive Raman spectroscopy in biological media. While safe levels of irradiation may be adequate to analyze superficial tissue, scattering of the pump beam reduces the Raman signal to…

This study presents the development of an integrated device for measuring magnetoelastic resonance, utilizing a gain/phase detector and the Arduino platform. The device stands out for its simplicity, low cost, and efficiency. It employs the…

Instrumentation and Detectors · Physics 2025-05-05 Wenderson R. F. Silva , Rafael O. R. R. Cunha , Joaquim B. S. Mendes

Raman spectroscopy is a powerful tool for material characterization. However, careful preprocessing is required for the identification and handling of noise, baseline drift, and random spikes. This paper presents a comprehensive approach to…

2H-TaSe2 is a model transition metal dichalcogenide material that develops charge density waves (CDWs).Here we present variable-temperature Raman spectroscopy study on both incommensurate charge density waves (ICDW) and optical phonon modes…

Materials Science · Physics 2017-12-13 Lin Cui , Qiaoling Huang , Gaomin Li , Yumeng You , Mingyuan Huang

Thermal properties have an outsized impact on efficiency and sensitivity of devices with nanoscale structures, such as in integrated electronic circuits. A number of thermal conductivity measurements for semiconductor nanostructures exist,…

Optical parametric oscillation (OPO) in a microresonator is promising as an efficient and scalable approach to on-chip coherent visible light generation. However, so far only red light at < 420 THz (near the edge of the visible band) has…

Optics · Physics 2022-07-21 Xiyuan Lu , Gregory Moille , Ashutosh Rao , Daron Westly , Kartik Srinivasan

Nonlinear pulse propagation in gas-filled waveguides has attracted substantial attention over the past decade, and a variety of capabilities have been reported. However, there is no prior report of spectral compression in gas-filled…

Optics · Physics 2026-03-24 Zegui Wang , Yi-Hao Chen , Yunlong Mo , Zaitian Dong , Wanhong Yin , Frank Wise , Wei Cao

This work focuses on the development and demonstration of tunable superconducting on-chip resonator, leveraging the intrinsic current-dependent non-linear kinetic inductance of superconducting aluminium, and investigating the effect of…

Instrumentation and Methods for Astrophysics · Physics 2026-05-08 Patrick Ashworth , Peter S. Barry , Chris S. Benson , Harry Gordon-Moys , Izaak Morris

Performant on-chip spectrometers are important for advancing sensing technologies, from environmental monitoring to biomedical diagnostics. As device footprints approach the scale of the operating wavelength, previously strategies,…

Tumor organoid-on-a-chip platforms represent a cutting-edge fusion of patient-derived organoids with microfluidic technologies, offering unprecedented capabilities for personalized cancer research. These systems overcome limitations of…

Tissues and Organs · Quantitative Biology 2025-07-30 Keyvan Alavi

The nanoconfinement of water can result in dramatic differences in its physical and chemical properties compared to bulk water. However, a detailed molecular-level understanding of these properties is still lacking. Vibrational…

Materials Science · Physics 2023-08-21 Rui Hou , Chu Li , Ding Pan

We developed a method for measuring blood coagulation using superparamagnetic iron oxide nanoparticles (SPIONs) and an alternating magnetic field (AMF). The 3rd and 5th harmonic signals from SPIONs mixed with blood induced by AMF were…

Medical Physics · Physics 2019-01-08 Kenya Murase

We develop a high speed on-chip flux measurement using a capacitively shunted SQUID as an embedded cryogenic transducer and apply this technique to the qualification of a near-term scalable printed circuit board (PCB) package for frequency…

Histopathology, the current gold standard for cancer diagnosis, involves the manual examination of tissue samples after chemical staining, a time-consuming process requiring expert analysis. Raman spectroscopy is an alternative, stain-free…

Development of high-speed, spatial-mapping spectrometers in the millimeter and far-infrared frequencies would enable entirely new research avenues in astronomy and cosmology. An "on-chip" spectrometer is one such technology that could…

Instrumentation and Methods for Astrophysics · Physics 2025-11-05 Matthew A. Koc , Jason Austermann , James Beall , Johannes Hubmayr , Joel N. Ullom , Michael Vissers , Jordan Wheeler

Conventional spectrometers are limited by trade-offs set by size, cost, signal-to-noise ratio (SNR), and spectral resolution. Here, we demonstrate a deep learning-based spectral reconstruction framework, using a compact and low-cost on-chip…

Angle-resolved Raman spectroscopy (ARRS) is an effective method to analyze the symmetry of phonons and other excitations in molecules and solid-state crystals. While there are several configurations of ARRS instruments, the measurement…

Microwave spectroscopy is a powerful experimental tool to reveal information on the intrinsic properties of superconductors. Superconducting stripline resonators, where the material under study constitutes one of the ground planes, offer a…

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